Clinical trials: Vaccination Pain
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Children's Distress During Flu Vaccination
Reducing Children's Distress Towards Flu Vaccinations
Millions of children in North America receive an annual flu vaccination, many of whom are at risk of experiencing severe distress. Children frequently use technologically advanced devices such as computers and cell phones.
- Trial name
- NCT01529021
- Where
- Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Immunization, Human Influenza
Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System
Study on Evaluating the Promote Effect of Yili Mei Yi Tian Active Lactobacillus Drink on Immunity and Physical Intestinal Canal
- Conditions
- Immunization, Human Influenza, Common Cold, Constipation
- Trial name
- NCT01677715
- Testing
- Yili "Mei Yi Tian" active lactobacillus drink, recombined milk drink contains no lactobacillus
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Pain, Injection Site Reaction
Safety of Pediatric COVID-19 Vaccination
This is a prospective, observational study. During the study, children and adolescents (ages ≥ 5 to < 16) will be followed post administration of mRNA COVID-19 vaccines.
- Conditions
- Pain, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05157191
- Testing
- Observational
- Where
- 5 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Duke University
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Infant, Pain
Kangaroo Care Reduces Infant Pain Caused By Vaccination
The aim of this randomized controlled study determine the effect of KMC on pain in infants during vaccination.
- Conditions
- Infant, Pain, Kangaroo Mother Care, Nursing
- Trial name
- NCT04596137
- Testing
- İnfant pain management
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Pain
Effectiveness of Helfer Skin Tap Technique and ShotBlocker Technique
The purpose of this study is to examine the effectiveness of the Helfer Skin Tap Technique and the ShotBlocker Technique in reducing pain in babies receiving intramuscular vaccination.
- Trial name
- NCT06246266
- Testing
- Helfer Skin Tap Technique group, ShotBlocker Technique group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Pain
Reduction of Pain in Childhood Vaccination in the Primary Care Nurse Vaccination Consultation
Non-randomized study with control group (CG) with the objective of analyzing the non-pharmacological analgesic efficacy of the "Painless Vaccine" protocol for the reduction of pain during vaccination in the population aged 2…
- Trial name
- NoVacPain (NCT06004258)
- Testing
- Painless Vaccination
- Where
- Spain
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen Macarena
Pain, Anxiety
Effects of Mother-Sung Lullabies on Infant Pain and Maternal Anxiety
Childhood pain can cause long-term and psychologically harmful effects. Music can reduce pain and anxiety. This study aimed to investigate the effects of the mother-sung lullaby during vaccine administration on vaccine-induced…
- Trial name
- NCT04692584
- Testing
- The Lullaby Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Pain
The Effect of ShotBlocker on Pain and Satisfaction During Measles-Rubella-Mumps Vaccination
Objective The aim of this study was to evaluate the effects of ShotBlocker administration during measles-mumps-rubella (MMR) vaccination on infants' pain level and mothers' satisfaction. Method.
- Trial name
- NCT06762938
- Testing
- ShotBlocker
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Immunization
Prenatal Education About Infant Immunization Pain Management
There are numerous pain management strategies available for the management of infant immunization pain. The majority of infants, however do not benefit from these interventions, which causes them to suffer pain unnecessarily.
- Trial name
- NCT01707212
- Testing
- Pain management education, No pain management education
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy Infants, Immunization
A Study of Two Injection Techniques to Reduce Pain in Infants Undergoing Immunization
Immunization injections are a significant source of pain for infants. Tactile stimulation (rubbing/applying pressure) may be an effective and feasible pain-relieving intervention - it is cost neutral, and has been shown to be…
- Conditions
- Healthy Infants, Immunization, Pain Management
- Trial name
- NCT01601197
- Testing
- Tactile stimulation
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Postpartum Women
A Hospital-based Postnatal Parent Education Intervention About Infant Immunizations
Immunization injections are the most common recurring painful medical procedure undertaken in childhood. Numerous evidence-based and feasible interventions are available to mitigate immunization pain, however, there is low uptake…
- Trial name
- IIAP (NCT01937143)
- Testing
- Low intensity intervention, High intensity intervention, Control
- Where
- Canada
- Volunteers
- 3,420 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Individual Satisfaction, Pain Management
The Effect on Pain and Satisfaction of Two Different Non-Pharmacological Methods Used During Coronavirus (Covid-19) Vaccination
The aim of this study was to determine the effect on pain and satisfaction during the administration of Covid-19 vaccination of two different non-pharmacological methods: squeezing a stress ball and placing Buzzy® on the…
- Trial name
- NCT05514262
- Testing
- The stress ball, The Buzzy® device
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uludag University
Acute Pain
Improving Parental Soothing by Video
This study sets out to compare the effectiveness of a parent pain management coaching video that is 5-minutes in length. The investigators will be comparing an active-video to a placebo-video of equal length (and identical…
- Trial name
- NCT01826383
- Testing
- Active-Video
- Where
- 2 sites in Canada
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- York University
Pain From Immunization
Reducing Pain in Four- to Six-month Old Infants Undergoing Immunization Using a Multi-modal Approach
The aim of this study is to answer the following question: In healthy infants aged four to six months undergoing routine immunization for diphtheria, tetanus, acellular pertussis, inactivated poliovirus and Haemophilus influenzae…
- Trial name
- NCT00954499
- Testing
- Tactile stimulation added to Standard care, Standard care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Procedural Pain
A Test of the Effectiveness of a Device and Distraction for Pediatric Immunization Pain
The hypothesis of this study is that distraction cards used by the caretaker along with a vibrating cold pack placed proximal to the site of immunization will decrease the pain of routine pediatric immunizations when compared to…
- Trial name
- NCT01152489
- Testing
- Device: Buzzy
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- MMJ Labs LLC
Pain
Thermal Analgesia in Newborns
Newborns routinely experience pain associated with invasive procedures such as blood sampling, immunization, vitamin K injection, or circumcision.
- Trial name
- NCT00740298
- Testing
- sucrose, warmth
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain Due to Childhood Vaccination
Distraction and Vibration for Minimizing Pain During Childhood Vaccination
Vaccine pain control is one of the actions suggested to support the delivery of vaccines that are on a vaccine schedule, since pain and anxiety associated with vaccines are among the main reasons why children and their parents…
- Trial name
- NCT03540589
- Testing
- Buzzy specific vibration device, Distraction
- Where
- Brazil
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Hospital Nossa Senhora da Conceicao
Pain, Vaccination Adverse Event
A Study to Assess the Acceptability and Usability of a New Device for Intradermal Vaccination
The aim of this study was to assess the acceptability and usability of a newly developed intradermal device in healthy adults
- Trial name
- NCT01963338
- Testing
- Intradermal injection in the forearm (0,1cc NaCl 0,9%), Intradermal injection in the upper arm (0,1cc NaCl 0,9%), Intramuscular injection in the upper arm (0,5cc NaCl 0,9%)
- Where
- Belgium
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Pierre Van Damme