Clinical trials: Vaginal Bleeding
Post Partum Hemorrhage
Amr Maneuver for Prevention of Postpartum Hemorrhage
The patients were divided randomly in to 2 GROUPS: control group: 153 patients received Oxytocin 10 IU I.V shot administered at the time of delivery of the anterior shoulder of the baby according to the WHO recommendation for…
- Trial name
- NCT04401839
- Testing
- Oxytocin IV shot, Oxytocin IV drip, Amr maneuver
- Where
- Egypt
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Cairo University
Instrumental Vaginal Births, Oxytocin Augmentation for Labor
The Swedish Birth Seat Trial
The purpose of this study is to determine whether birth on a birthing seat will effect numbers of instrumentally assisted vaginal births, vaginal traumas, blood loss,use of artificial oxytocin for labour augmentation and fetal…
- Conditions
- Instrumental Vaginal Births, Oxytocin Augmentation for Labor, Maternal Blood Loss, Perineal Outcomes
- Trial name
- NCT01182038
- Testing
- BirthRite birthing seat
- Where
- Sweden
- Volunteers
- 1,002 people, healthy volunteers welcome
- Sponsor
- Helsingborgs Hospital
Uterine Atony, Postpartum Hemorrhage
An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery
The purpose of this study will be to evaluate a standardized, evidence-based protocol versus a conventional approach for the dosing of oxytocin in vaginal delivery.
- Trial name
- NCT02410655
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Vaginal Bleeding, Uterine Cramping
Anticipatory Counseling on LNG-IUS Continuation, Utilization and Satisfaction
This study is a counseling intervention for new LNG-IUS users. The study explores the use of video technology to deliver anticipatory counseling on LNG-IUS side-effects, adjustment periods and bleeding changes to women newly…
- Trial name
- ACCCUSS (NCT02752282)
- Testing
- Anticipatory Counseling, Cancer Screening Guidelines
- Where
- 3 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Washington
Myoma;Uterus
Preoperative Vaginal Dinoprostone Versus Misoprostone in Abdominal Myomectomy
Aim and objectives; To compare the efficacy of preoperative administration of dinoprostone 20 mg versus 400 ug misoprostol vaginally in decreasing the amount of bleeding during abdominal myomectomy
- Trial name
- NCT05761418
- Testing
- Dinoprostone, Misoprostol
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-1 (NCT03789799)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Placental Bleeding
Placental Drainage Versus no Placental Drainage After Vaginal Delivery in the Management of Third Stage of Labour
In this randomized controlled study, 222 pregnant women who admitted to Zeynep Kamil Women and Children's Health Training and Research Hospital from December 2016 and July 2017 were included.
- Trial name
- NCT03542292
- Testing
- placental drainage
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Pharmacokinetics, Safety Issues
PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
A double-blind, randomized trial (1:1) to characterize the local and systemic pharmacokinetics (PK) of two DPV-LNG vaginal ring formulations
- Conditions
- Pharmacokinetics, Safety Issues, Bleeding
- Trial name
- NCT05041699
- Testing
- IPM Ring-105, IPM Ring-106
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Healthy, Contraception
PK Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel
This is a Phase I single-center, two-arm, open-label, randomized study in healthy HIV-negative women to evaluate the pharmacokinetics, safety, and bleeding patterns associated with 90-day use of matrix vaginal rings containing…
- Conditions
- Healthy, Contraception, Contraceptive Usage, Women
- Trial name
- NCT03467347
- Testing
- VR: 200 mg DPV + 320 mg LNG
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Postpartum Haemorrhage
Carbetocin Versus Syntometrine for the Third Stage of Labour
Intramuscular carbetocin is as effective as intramuscular syntometrine for the prevention of postpartum haemorrhage
- Trial name
- NCT00499005
- Testing
- Syntommetrine and Carbetocin
- Where
- Singapore
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Uterine Fibroids, Abnormal Uterine Bleeding
Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?
The objective aim is to evaluate whether the use of 3D laparoscopy facilitates the vaginal cuff closure of the vaginal cuff during a total laparoscopic hysterectomy among novice laparoscopists (PGY 2-4, Fellow).
- Conditions
- Uterine Fibroids, Abnormal Uterine Bleeding, Pelvic Pain, Adenomyosis
- Trial name
- 3DRCT (NCT02192606)
- Testing
- Storz 3D Laparoscopy System, 2D Laparoscopy
- Where
- 2 sites in United States, Denmark
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Abnormal Uterine Bleeding, Uterine Bleeding
Outcomes on Abdominal Versus Vaginal Morcellation At Time of Hysterectomy
The purpose of the study is to investigate differences in perioperative and postoperative outcomes between the abdominal (AM) versus vaginal (VM) routes of contained morcellation in participants undergoing laparoscopic total…
- Conditions
- Abnormal Uterine Bleeding, Uterine Bleeding, Fibroid Uterus, Surgery
- Trial name
- NCT04434066
- Testing
- Total Laparoscopic Hysterectomy
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Postpartum Hemorrhage
Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery
The aim of this study is to evaluate the impact of a rotational thromboelastometry (ROTEM®)-based transfusion protocol during postpartum hemorrhage (PPH) after vaginal or cesarean delivery.
- Trial name
- NCT03064152
- Testing
- Rotational Thromboelastometry
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Uterine Fibroids, Vaginal Bleeding
Optimal Order of Concurrent Office Hysteroscopy and Endometrial Biopsy
This study will look at the optimal order in which to perform concurrent office hysteroscopy and endometrial biopsy in female patients who present for evaluation of abnormal uterine bleeding at a fibroid and endometriosis…
- Trial name
- NCT02472184
- Testing
- Office hysteroscopy, Endometrial biopsy
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Atrophy of Vagina, Vaginal Ulceration
Vaginal Creams to Reduce Vaginal Erosion in Pessary Users
To compare the use of Estrace ® vaginal cream against a placebo vaginal cream in reducing symptomatic vaginal discharge and vaginal erosion in patients who are using the Gellhorn or Ring with support pessaries.
- Conditions
- Atrophy of Vagina, Vaginal Ulceration, Vaginitis
- Trial name
- NCT02316249
- Testing
- Estradiol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Vaginal Bleeding
Tamoxifen Versus Estradiol for Unscheduled Bleeding in Etonogestrel Implant Users, a Randomized Pilot Trial
The purpose of this research study is to evaluate the ability of medicines called tamoxifen or estradiol to prevent annoying vaginal bleeding for arm implant users.
- Trial name
- NCT04933240
- Testing
- Tamoxifen Citrate 10Mg Tab, Estradiol
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Postpartum Hemorrhage, Vaginal Delivery
Prophylactic Tranexamic Acid Use After Vaginal Delivery
In this study, our aim was to evaluate the effectiveness of prophylactic tranexamic acid use after vaginal delivery in pregnant women aged 18-45 years and 34-42 weeks according to the risk of postpartum hemorrhage.
- Conditions
- Postpartum Hemorrhage, Vaginal Delivery, Prophylactic Tranexamic Acid Use
- Trial name
- NCT05429580
- Testing
- Tranexamic acid, 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital