Clinical trials: Vaginal Delivery
Postpartum Hemorrhage, Carbetocin
Timing of Carbetocin Administration in Postpartum Hemorrhage
Postpartum haemorrhage (PPH) is one of the major contributors to maternal mortality and morbidity worldwide. Active management of the third stage of labour has been proven to be effective in the prevention of PPH.
- Trial name
- NCT06776926
- Testing
- Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mehmet Mete Kırlangıç
Cesarean and Vaginal Birth Complications
Assessment of Lumbar Spine Active Range of Motion in Women Who Were Experienced Cesarean or Vaginal Birth
Pregnancy may impact the musculoskeletal apparatus of females through pregnancy-associated biomechanical, vascular, and hormonal changes. Pregnant females may complain of lumbopelvic pain, especially during their last trimester.
- Trial name
- NCT05538325
- Testing
- Bubble Inclinometer and Digital Pelvic Inclinometer
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- South Valley University
Pregnancy
Measuring Preferences for Childbirth After Cesarean
The objective of this proposed 18-month exploratory research study is to help pregnant women weigh risks and benefits in a childbirth decision using the Preferences-Assessment Computer Module.
- Trial name
- NCT00267735
- Testing
- Use of Computerized Decision Aid on Childbirth
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Induction of Labour, Prolonged Pregnancy
Outpatient Foley Catheter for Induction of Labor in Nulliparous for Prolonged Pregnancy
15 to 20 % of nulliparous needs an induction at term. None study has evaluated Foley catheter induction at home versus expectative in this population
- Trial name
- FOLOUT (NCT02932319)
- Testing
- Foley catheter, expectative
- Where
- 5 sites in France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Preterm Birth
Comparison Between Vaginal Pessary and Progestogen in Twin Pregnancy With Short Cervical Length
A randomized clinical trial comparing vaginal progestogen and vaginal pessary as an intervention for twin pregnancies with short cervical length.
- Trial name
- NCT04342585
- Testing
- Micronised vaginal progesterone, Vaginal pessary
- Where
- Malaysia
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Labor Pain, Comfort
Using Wet Towel During Labor
The goal of this clinical trial is to learn whether the wet towel method applied during the first stage of labor can reduce labor pain and anxiety and improve childbirth comfort in first-time mothers.
- Conditions
- Labor Pain, Comfort, Labor Anxiety
- Trial name
- NCT07808840
- Testing
- Wet Towel
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Pelvic Floor Disorders, Urinary Incontinence
Effects of Epi-no Device on Pelvic Floor Dysfunctions
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery. Perineal traumas are associated with maternal morbidity, including pain, urinary and fecal incontinence, genital prolapses…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Dyspareunia, Lacerations Perineal
- Trial name
- NCT04955418
- Testing
- Epi-No®, Evaluation
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Labor, First Stage, Labor, Second Stage
Effect of Dianatal Obstetric Gel (Cross-linked Polyacrylic Acid) on Outcomes in Vaginal Delivery
Perineal massage at the end of labor stage 2 has been investigated in 2 randomized controlled trials using a water soluble lubricant.
- Trial name
- NCT01546129
- Testing
- Dianatal Obstetric Gel (Cross-linked polyacrylic acid)
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Postpartum Hemorrhage
Effect of Adjunctive Misoprostol Treatment on Blood Loss at Vaginal Delivery
This document defines the Clinical Investigation Protocol for a study designed to determine whether blood loss after spontaneous vaginal delivery is altered by the addition of misoprostol administration to the standard use of…
- Trial name
- NCT02411916
- Testing
- misoprostol
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Antifungal Drug Adverse Reaction
An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women
To evaluate the pharmacokinetics (PK) of EE and NES released from the CVR in the presence of a single dose and multiple doses of antimycotic co-medication (miconazole nitrate suppository or cream).
- Trial name
- NCT02215395
- Testing
- NES/EE CVR
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Population Council
Birth, First, Experience, Life
The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial
Vaginal examination contains many negative emotions such as pain, fear, stress, and discomfort for women. When the literature was examined, no study was found in which the focus method was used to reduce or eliminate the feelings…
- Conditions
- Birth, First, Experience, Life, Pain
- Trial name
- NCT05471219
- Testing
- Primiparous pregnant women who will undergo vaginal examination by focusing on visual traces
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dilek Yigit Vural
Perineal Infection, Maternal Infections Affecting Fetus or Newborn
Different Perineal Preparations Before Vaginal Birth to Maternal/Neonatal Infections and Cost Effectiveness
The vaginal microbiome plays a crucial role in women's health, primarily composed of beneficial bacteria such as Lactobacillus, which help maintain an acidic environment in the vagina, preventing the growth of pathogens.
- Conditions
- Perineal Infection, Maternal Infections Affecting Fetus or Newborn, Cost Effectiveness
- Trial name
- NCT06880445
- Testing
- Povidone-Iodine (PVP-I), Water
- Where
- Taiwan
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tzu-Ying Huang
Premature Birth
Vaginal Progesterone in Twins With Short Cervix
A Multicenter, Double-Blind, Placebo-Controlled Randomized Clinical Trial of Vaginal Progesterone to Prevent Early Preterm Birth In Twin Pregnancy with Short Cervix.
- Trial name
- NCT01812239
- Testing
- Vaginal Progesterone gel., fetal fibronectin swab.
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Obstetrix Medical Group
Fatigue, Comfort
Hot Showers on Postpartum Fatigue, Mood and Comfort In Women Giving Vaginal Birth
The aim of this study to determine the effect of hot showers on postpartum fatigue, mood and comfort in women giving vaginal birth.
- Conditions
- Fatigue, Comfort, Mood, Postpartum Care
- Trial name
- NCT04848922
- Testing
- Hot shower intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
First Pregnancy, Vaginal Delivery
Therapeutic Touch on Labour Pain, Anxiety and Childbirth Attitude
Introduction: Touching ensures physical, emotional and spiritual relaxation, confidence, peace, calmness and well-being, and increases self-esteem.
- Trial name
- touch (NCT04543487)
- Testing
- Therapeutic touch
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Vaginal Laxity
Correlation Between Vaginal Laxity and Delivery Mode
Evaluation of pelvic floor using 2D and 3D Transperineal Ultrasound
- Trial name
- NCT07517978
- Testing
- Transperineal Ultrasound
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Labor Pain, Pain Relief
fMRI Measurements on Pain Relief Methods in First Stage Labor Pain
The purposes of this study is to integrate the objective tests into the subjective test, visual analog score (VAS), for evaluation and further understanding of relieving labor pain by TENS application on acupuncture points in the…
- Conditions
- Labor Pain, Pain Relief, Magnetic Resonance Imaging
- Trial name
- TENS (NCT00768014)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
HIV Infections
Feasibility Study of a Vaginal Ring for Delivery of TMC120 (Dapivirine)
The purpose of this trial was to evaluate the safety and feasibility of using a vaginal ring to deliver the candidate microbicide TMC120 (dapivirine).
- Trial name
- NCT00700284
- Testing
- TMC120 (dapivirine) vaginal ring
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.