Clinical trials: Vaginismus
Female Sexual Dysfunction
Female Sexual Dysfunction Assessment and Managment of Vaginismus
The study aims at : 1. The extent female sexual dysfunction problem in community through questionnaire . 2. Compare effectiveness of two treatment options for vaginismus .
- Trial name
- NCT06755099
- Testing
- Botox, Radiofrequency
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Vaginismus
Botulinum Toxin Injection for Treatment of Vaginismus
According to high rate of vaginismus (about 10 percent) which leads to unconsummated marriage (about 1 percent) and low efficacy for conventional treatments such as biofeedback therapy, analgesic drugs and pain killers and…
- Trial name
- NCT00638066
- Testing
- botulinum toxin, botulinum toxin A
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Vaginismus, Vaginal Atrophy
Hydration and Acceptability of the Genital and Skin Mucosa of a Vaginal Moisturizer in Menopausal Women
Hyaluronic Acid is indicated for the relief of vaginal dryness, itching, and irritation, or the reduction of vaginal lubrication with prolonged hydration effects for up to 72 hours.
- Conditions
- Vaginismus, Vaginal Atrophy, Menopause
- Trial name
- NCT06564883
- Testing
- 0.20% sodium hyaluronate gel
- Volunteers
- 45 people
- Sponsor
- Biolab Sanus Farmaceutica
Vaginismus
Virtual Reality Exposure for Vaginismus: A Replicated Single-Case Design
Vaginismus is a sexual dysfunction characterized by involuntary tightening of the pelvic floor muscles, preventing vaginal intercourse.
- Trial name
- VIVID 2 (NCT06923306)
- Testing
- Virtual reality exposure
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Pelvic Floor Dyssynergia
Baclofen/Diazepam Supps for Treatment of Pelvic Floor Myalgia
This study is a randomized, placebo controlled double blind cross over trial. Patients presenting with pelvic floor myalgia will be asked to complete a series of standardized questionnaires to assess their pain, quality of life…
- Trial name
- BDS (NCT03427216)
- Testing
- Baclofen/diazepam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. John A. Thiel Medical Professional Corporation
Myofacial Pain, Pelvic Pain
Measuring Pelvic Floor Muscle Fitness Before and After Treatment
This study is being done to better understand and improve treatment for myofascial pelvic pain, a common cause of long-lasting pelvic pain in women.
- Conditions
- Myofacial Pain, Pelvic Pain, Myofascial Pelvic Pain, Chronic Pelvic Pain
- Trial name
- NCT07605598
- Testing
- Near Infrared Imaging
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Vaginismus
Botox Injection for Treatment of Vaginismus
The use of Botox injections intravaginally and progressive dilation under anesthesia has been shown to cure vaginismus. This study expands the use of Botox injections to include progressive dilation, post procedure supervised…
- Trial name
- NCT01352546
- Testing
- BOTOX
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Plastic Surgery Professional Association
Dyspareunia
What is the Nature of Pelvic Floor Muscle Involvement in Dyspareunia?
Dyspareunia, or pain experienced by women during penetrative sexual activities, affects the psychological and sexual health of more than one in five Canadian women [1], yet its pathophysiology is poorly understood [2-4] and…
- Trial name
- NCT04234555
- Testing
- Corticomotor excitability to the pelvic floor muscles, Pelvic floor muscle response to pressure applied at the vulvar vestibule, Pressure pain threshold (PPS)
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Vaginismus
Immersive Visual Modulation and Ambient Music Therapy During Transvaginal Ultrasonography in Women With Vaginismus
Vaginismus is a sexual dysfunction characterized by involuntary contractions of the pelvic floor muscles that prevent vaginal penetration. This condition is often associated with intense fear, anxiety, and avoidance behaviors.
- Trial name
- NCT07734454
- Testing
- Standard Care, Immersive Visual Modulation (IVM), Ambient Music Therapy (AMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Demet Mutlu
Vaginismus, Difficulties With Vaginal Penetration
Implementing Virtual Reality Exposure Therapy for Vaginismus: From Efficacy to Clinical Integration (VIVID 3)
Vaginismus, a condition characterized by involuntary tightening of the pelvic floor muscles due to strong fear of vaginal insertion, impact ≥6% of the female population and can make vaginal intercourse and medical exams…
- Trial name
- VIVID 3 (NCT07747298)
- Testing
- Implementation of Virtual Reality Exposure
- Where
- Canada
- Volunteers
- 167 people
- Sponsor
- University of British Columbia
Women Health, Physiotherapy
Pelvic Floor Physiotherapy Combined With Sexual Therapy in Vaginismus Treatment
Studies on pelvic floor physiotherapy in individuals diagnosed with vaginismus are quite limited in the literature. While current studies have focused on certain physiotherapy modalities, the literature is quite limited in terms…
- Conditions
- Women Health, Physiotherapy, Exercise
- Trial name
- NCT06760767
- Testing
- sexual therapy, Pelvic floor physiotherapy combined with sexual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medipol University
Vaginismus, Dyspareunia
Prospective on Market Patient-reported Outcomes for Milli
To assess the effectiveness of the Milli device in achieving vaginal intercourse
- Trial name
- POMPOM (NCT06397885)
- Testing
- Milli Vaginal Dilator
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Materna Medical
Placenta Praevia, Vaginismus
Transperineal Ultrasound to Assess the Progress of Labour
This is a prospective observational study of transperineal ultrasound between 24-42 weeks gestation and a prospective longitudinal observational study in all term (37-42 weeks) labouring women.
- Trial name
- NCT02430038
- Where
- United Kingdom
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Vaginismus
Feasibility of Use of Vibrators With Vaginal Dilators for Vaginismus. (Vibrator Therapy and Dilators in Vaginismus)
The acceptability of vulvar vibration therapy has been evaluated in women with vulvodynia, and found to be acceptable, however has not been assessed in women with a primary complaint of vaginismus.
- Trial name
- ViTaDiVa (NCT04635345)
- Testing
- External Vibrator - patient-administered., Standard care
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Pelvic Floor Dysfunctions
Effectiveness of Modern Physical Agents in the Treatment of Pelvic Floor Dysfunctions
This clinical trial aims to determine whether adding modern physical agents (high-intensity laser therapy, magnetotherapy, radial shock wave therapy, kinesiotaping) in conjunction with classical rehabilitation interventions…
- Trial name
- EMPHAT-PFD (NCT06800222)
- Testing
- modern agents rehab, classical rehab
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Lithuanian University of Health Sciences
Vaginismus
Effect of Adding Interferential Current to Pelvic Floor Muscle Training on Vaginismus
This study aims to determine the effect of adding interferential current to pelvic floor muscle training on vaginismus.
- Trial name
- NCT06486896
- Testing
- Pelvic floor training, Interferential current, General advice
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pelvic Pain, Levator Ani Syndrome
Photobiomodulation for Myofascial Pelvic Pain
The goal of this clinical trial is to evaluate the efficacy of photobiomodulation of the pelvic floor muscles in female Veterans with chronic pelvic pain.
- Conditions
- Pelvic Pain, Levator Ani Syndrome, Spastic Pelvic Floor Syndrome, Chronic Pelvic Pain Syndrome
- Trial name
- PMPP (NCT05926752)
- Testing
- SoLá therapy, Pelvic floor physical therapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Orlando VA Medical Center
Vaginismus, Psychological Distress
Effectiveness of Cognitive Behavioral Therapy on Psychological Distress and Problem-Solving Skills in Women With Vaginismus
This randomized controlled trial aimed to evaluate the effectiveness of a structured cognitive behavioral therapy (CBT) intervention on psychological distress and problem-solving skills among women with vaginismus.
- Trial name
- CBT-VAG (NCT07588724)
- Testing
- Cognitive Behavioral Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Dyspareunia, Hypoactive Sexual Desire Disorder
Sexual Dysfunction and Dental Care
Evaluation of sexual functioning of patients at the Sexual Medical Center, at Sheba Medical Center in Israel. Sexual functioning shall be compared with their dental behavior. Hypothesis: a positive association will be found.
- Conditions
- Dyspareunia, Hypoactive Sexual Desire Disorder, Erectile Dysfunction, Vaginismus
- Trial name
- NCT00281372
- Volunteers
- 448 people
- Sponsor
- Sheba Medical Center