Clinical trials: Validation Studies
Reliability of National Quality Indicator Data
Data Quality of National Quality Indicators in Long-term Care Facilities: a Validation and Evaluation Study
This multiple-methods study with two data collection points (T0 and T1) aims to: 1. assess inter-rater reliability of the six national quality indicators in long-term care facilities (LTCFs) for older people in Switzerland (T0)…
- Trial name
- NIP-Q-UPGRADE (NCT06160024)
- Testing
- Program to improve data quality of national quality indicators
- Where
- 3 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Basel
Ultrasonography
Detection of Muscle Quality in Children - Protocol for a Validation Study
The goal of this observational study is to evaluate the validity and reliability of ultrasound echo intensity (EI) as a diagnostic tool for assessing muscle quality in children aged 10-14 years, including normal-weight, obese…
- Trial name
- NCT06792279
- Where
- Czechia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Cardiovascular Risk Factor, Cardiovascular Diseases
VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study
Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Atherosclerosis of Artery
- Trial name
- NCT04303546
- Testing
- arterial stiffness measurements
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Validation
Validity and Feasibility of Newborn Bed Monitoring Device - a Clinical Pilot Study
The aim of this clinical pilot study is to evaluate the validity, acceptability and usability of the newborn bed monitoring device among newborns, parents and healthcare professionals in hospital environment.
- Trial name
- NCT06679127
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Anna Axelin
Epithelial Ovarian Cancer, Primary Cytoreduction
Cukurova Score Validation Study
Despite significant advancements in imaging technologies, surgical techniques, chemotherapeutic regimens, and treatment strategies in recent years, ovarian cancer continues to remain the most deadly gynecological malignancy.
- Trial name
- CUKUROVA (NCT06378905)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Healthy
Nonin 4 Wavelength Cerebral Oximeter Study
A cerebral oximeter is a device that uses light to measure the amount of oxygen within the brain. It is similar to the device that measures the level of oxygen in the tip of the finger, known as a pulse oximeter.
- Trial name
- Nonin4 (NCT01762722)
- Testing
- Reduction of inspired oxygen
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duke University
Measure Accuracy of Respiratory Rate
Respiratory Rate Validation Study
The purpose of this study is to conduct a Respiratory Rate accuracy validation on pediatrics population comparing the Gabi SmartCare Gabi Band to the Reference, an FDA cleared End Tidal Carbon Dioxide monitor (GE Datex- Ohmeda)…
- Trial name
- NCT05856422
- Testing
- Respiratory rate measure based on PPG
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gabi SmartCare
Pulse Oximetry
SpO2 Validation Study - Philips FAST 2024
Validation study to compare the accuracy of non-invasive Philips SpO2 sensors in detecting blood oxygen levels compared to invasive methods requiring a blood draw and lab analysis.
- Trial name
- FAST 2024 (NCT06484452)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Dilated Cardiomyopathy
Exercise Stress MRI to Evaluate Aortic Function (Compliance, Distensibility, Pulse Wave Velocity) and Left Ventricular Function : Validation in Healthy Volunteers and in Selected Patients. A Pilot Study.
Detecting abnormalities in the left ventricular mechanical and hemodynamic response to the stress of exercise may offer early diagnostic indicators in patients suffering from valvular disease such as mitral regurgitation.
- Trial name
- NCT02018835
- Testing
- MRI, cardiac echography transthoracic
- Where
- France
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Oral Health
Validation Of The Turkish Version Of The Oral Assessment Sheet
The aim of this observational study is to evaluate the validity and reliability of the Turkish version of the Oral Assessment Sheet (OAS).
- Trial name
- OAS-TR (NCT07507864)
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Minimally Invasive Surgery Basic Skills
Goal-directed MIS Simulation Training With the LTB-Curriculum Prior to First Operations on Patients: Study Protocol for a Multi-centre Randomized Controlled Validation Trial (NOVICE)
Background: Laparoscopic surgical procedures have become increasingly established in operative medicine. They require special motor, haptic, and spatial-visual skills to perform the interventions safely and effectively.
- Trial name
- NOVICE (NCT03040544)
- Testing
- LTB-Curriculum, Laparoscopic cholecystectomy
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Microbiome, Stress
Investigating the Detection of Bovine and Soy Proteins in Human Milk
This study is a randomized, cross-over, dietary intervention research design comprising a 5-day run-in period, two 3-day dietary interventions, and a 2-day washout period.
- Conditions
- Microbiome, Stress, Food Allergy in Infants
- Trial name
- NCT04851340
- Testing
- Cow's Milk, Soy Milk
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Idaho
Rotator Cuff, Syndrome, Frozen Shoulder
Validation of a Kinematic Functional Shoulder Score Including Only Essential Movements
A lot of shoulder function evaluation scores exist but none has been universally accepted as a gold standard. Recent studies have demonstrated the potential of computerized movement analysis with embedded sensors for objective…
- Conditions
- Rotator Cuff, Syndrome, Frozen Shoulder, Humerus, Fracture, Other Instability of Joint, Shoulder Region
- Trial name
- NCT01431417
- Where
- Switzerland
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Cancer
Pan-canceR Early DetectIon projeCT (PREDICT)
PREDICT is a prospective, multicenter study for the early detection of pan-cancer through cell-free DNA (cfDNA) methylation-based model, in which approximately 14,000 participants will be enrolled.
- Trial name
- NCT04817306
- Testing
- Multi-cancer early detection test
- Where
- 3 sites in China
- Volunteers
- 14,026 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
In Utero Drug Exposure
Validation of the In-utero Transmission of Probiotics
This pilot project aims at confirming the in-utero transmission of probiotics, from the mother to the baby. Women aged 18 to 42 years, with a single pregnancy, considered low risk will be approached for this study.
- Trial name
- PROBIO (NCT04050189)
- Testing
- Natural products: Probiotics
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Dry Eye
Validation of Osmolarity System: Clinical Usability Study
Confirmatory trial to validate usability of a new portable osmolarity testing device.
- Trial name
- NCT03769324
- Testing
- Osmolarity Test
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- I-MED Pharma
Telomere Length
Telomere Length in Human Polar Body and Telomere Length in Cumulus Cells: A Clinical Validation Study
To investigate whether telomere length (TL) of the first Polar body (PB) correlates with TL in Cumulus cells (CC)
- Trial name
- NCT04577560
- Testing
- First polar body biopsy in MII oocytes, PGT-A blastocyst
- Where
- United Arab Emirates
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Attitude of Health Personnel
Manual Therapy Behavior Scale in Physiotherapists
The aim of this study is to develop a scale to assess the manual therapy application behaviors of physiotherapists in Türkiye, based on the Theory of Planned Behavior (Ajzen, 1991).
- Trial name
- NCT07296380
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Uşak University
Older Adults
The Development and Validation of the Arabic Otago Exercise Program
Falls are common in older adults and may lead to disability or even death. Therefore, exercise programs that focus on preventing falls by improving strength and balance are important to investigate in older adults.
- Trial name
- NCT05002803
- Testing
- Otago Exercise Program
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Hepatocellular Carcinoma
Refinement and Validation of a Diagnostic Model (GAMAD) for Early Detection of Hepatocellular Carcinoma
Most hepatocellular carcinoma (HCC) cases were at advanced stage when diagnosis established. This study is intended to establish a clinical diagnostic model GAMAD for early-stage HCC and evaluate the diagnostic efficiency the…
- Trial name
- NCT05626985
- Testing
- GAMAD
- Where
- 3 sites in China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Singlera Genomics Inc.