Clinical trials: Validation Studies
Diet Habit
Validation of the eNutri Food Frequency Questionnaire for Adults Aged 65 y and Older
The aim is to determine whether the eNutri web application can effectively estimate the dietary intake of a UK older population.
- Trial name
- eNutriFFQ65+ (NCT04761575)
- Testing
- Validation of the FFQ65+ via eNutri app
- Where
- United Kingdom
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Reading
Proof of Concept Study
Measuring Hydrogen Peroxide in Exhaled Breath Condensate in COPD
Following a successful pilot study and a clinical assessment in healthy volunteers (ClinicalTrials.gov ID: NCT05844553) this study aims to evaluate the accuracy and precision of an Exhaled Breath Condensate (EBC) device in…
- Trial name
- NCT06788457
- Testing
- Exhaled Breath Condensate
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Lifestyle-related Condition, Nutrient; Excess
Dietary Quality Photo Navigation (DQPN) Preliminary Validation Study
The purpose of this research project is to conduct a preliminary validation study of the Diet Quality Photo Navigation (DQPN) method of dietary intake assessment.
- Trial name
- NCT03661931
- Testing
- DQPN Validation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Boston Heart Diagnostics
Retinopathy of Prematurity, ROP
Automated Screening Device to Detect MTMROP
The purpose of the study is to evaluate the i-ROP DL system for autonomous ROP screening. To demonstrate the sensitivity and specificity of the i-ROP DL system on images obtained by healthcare providers in the neonatal intensive…
- Trial name
- NCT06517836
- Testing
- iROP DL
- Where
- United States
- Volunteers
- 1,284 people, healthy volunteers welcome
- Sponsor
- Siloam Vision
Life Style, Healthy
Turkish Validation of the Core Life Activities Scale
This study aims to adapt the Core Life Activities Scale (CORE) into Turkish and evaluate its validity and reliability in Turkish-speaking adults.
- Trial name
- CORE-TR (NCT07762963)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Brain Injuries, Traumatic
Brain Oximeter Calibration and Validation Study
The purpose of the study is to calibrate and to validate the accuracy of the oximeter with an estimate of brain oxygen levels assessed by measuring arterial and internal jugular vein blood oxygen saturations.
- Trial name
- TPOT (NCT05397704)
- Testing
- brain pulse oximeter
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cyban Pty Ltd
Spinocerebellar Ataxia Type 27B
Spinocerebellar Ataxia Type 27B Natural History Study (SCA27B-NHS)
This international, multi-center, multi-modal, and prospective observational cohort study aims to validate trial outcomes for capturing disease progression in Spinocerebellar Ataxia Type 27B (SCA27B), with combined multi-modal…
- Trial name
- NCT06472557
- Where
- 5 sites in Czechia, Germany and 2 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Clinical Accuracy of Vital Sign Pressure Sensor
V-Sensors for Vitals: Assessment of the Accuracy of a Vital Sign Sensor Mounted on a Smartphone
This trial seeks to demonstrate clinical accuracy and safety of the integrated V-Sensor when used by the general, healthy adult population interested in measuring their vital signs outside of the clinical setting.
- Trial name
- NCT03321851
- Testing
- V-sensor device user
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Léman Micro Devices SA
Infertility
Eeva System Imaging Study
The purpose of this clinical trial is to collect imaging data on embryos followed to blastocyst stage (Day 5-6) for ongoing development and validation of the Eeva System.
- Trial name
- PROSPECT (NCT02301637)
- Testing
- Eeva™ Test
- Where
- 7 sites in United States, New Zealand
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Progyny, Inc.
Gastrointestinal Dysfunction
Gastric Emptying Validation Pilot Study (MRI Val)
The primary aim of this study is to assess (in healthy volunteers) the rate at which a glucose drink leaves the stomach by sequential magnetic resonance imaging (MRI) of the stomach contents using a 0.5 tesla upright MRI scanner…
- Trial name
- MRIVal (NCT05765123)
- Testing
- Oral glucose tolerance test
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Determine Validity of Concept of Using Hemoglobin Dilution to Assess/Measure Blood Volume.
Calculating Blood Volume by Dilution of Hemoglobin - Pilot Study
Although blood volume is such an important parameter in everyday clinical medicine it cannot be measured easily. As a matter of fact, it is almost never measured but estimated or calculated based upon numbers derived from mostly…
- Trial name
- NCT01900769
- Testing
- Blood Volume Dilution
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kai Schoenhage
Cardiovascular Risk Factor, Cardiovascular Diseases
VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study
Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Atherosclerosis of Artery
- Trial name
- NCT04303546
- Testing
- arterial stiffness measurements
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Bladder Disease, Bladder Retention Volume
ECHO-012 Kosmos Bladder Clinical Validation Study
The goal of this clinical trial is to compare the Kosmos Automatic Bladder Volume to the manual annotated bladder volume in participants across gender (male and female), age (children ages 7-17 and adults 18-89), and BMI strata…
- Conditions
- Bladder Disease, Bladder Retention Volume, Bladder Dysfunction, Bladder Function
- Trial name
- NCT06792851
- Testing
- Kosmos Bladder Volume Algorithm
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- EchoNous Inc.
COPD, ILD
Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases
This upcoming case-control study aims to confirm the Lung Sliding Index (LSI), a new ultrasound score that measures how well the pleura moves, in various lung diseases.
- Conditions
- COPD, ILD, Bronchiectasis, Pneumothorax
- Trial name
- NCT06983366
- Testing
- Lung Ultrasound
- Where
- Egypt
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gingival Recessions
AI-Based Prediction of Root Coverage Outcome From Intraoral Photographs
This study evaluates whether the outcome of root coverage surgery can be predicted from a preoperative intraoral photograph. Adults with Cairo RT1,RT2 or RT3 gingival recessions treated with a coronally advanced flap and a…
- Trial name
- NCT07775365
- Testing
- Coronally advanced flap with subepithelial connective tissue graft, Deep learning based prediction of root coverage outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Marmara University
Oxygen Saturation Measurement
Controlled Desaturation Study for Perin Health Patch Validation
This study aims to test the accuracy of the Perin Health Patch (PHP), a non-invasive, chest-worn device that measures blood oxygen levels, by comparing its readings to a standard pulse oximeter device.
- Trial name
- NCT06680700
- Testing
- Perin Health Patch
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Autism, Autism Spectrum Disorder
SenseToKnow Autism Screening Device Validation Study
This is a pivotal, prospective, double-blind, study to evaluate the sensitivity and specificity of the SenseToKnow device for the detection of autism spectrum disorder in children 16-36 months of age.
- Trial name
- NCT05874466
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Duke University
Cardiac Arrhythmia
Validation Study: Extended Wear Performance of the Zio Monitor - SHASTA II
This trial assesses the wear performance of the Zio monitor, a long-term continuous ambulatory patch ECG monitor, in a representative population by evaluating (1) the wear duration (up to 30 days) of the device, (2) the…
- Trial name
- NCT07205367
- Testing
- Zio Monitor
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- iRhythm Technologies, Inc.
SARS-CoV2 Infection
COVID-19 SARS-CoV-2 RAST Study
The SARS-CoV-2 BioMedomics Rapid Antigen Screening Test (COV-SCAN) is an at-home rapid antigen COVID-19 antigen screening test device.
- Trial name
- NCT06452056
- Testing
- Rapid Antigen Screening Test
- Where
- United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Columbia University
Dietary Assessment
Evaluation of the Nutri-plus Module
In this validation study, the validity of the Nutri-plus module will be investigated.
- Trial name
- NCT07459140
- Testing
- The Nutri-plus module
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- TNO