Clinical trials: Validation Studies
Traumatic Brain Injury
Validation Study of Simplified Chinese Version of LOTCA Scale in the Assessment of Cognitive Impairment in Patients with Traumatic Brain Injury
In this study, 300 patients aged ≥18 years old with traumatic brain injury (case group) and hospitalized patients without central nervous system disease or their family members and accompanying staff (control group) were selected…
- Trial name
- NCT06850584
- Testing
- Observation
- Where
- 4 sites in China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Nanjing Broad Biopharmaceutical Ltd.
Pulse Oximetry
SpO2 Validation Study - Philips FAST 2024
Validation study to compare the accuracy of non-invasive Philips SpO2 sensors in detecting blood oxygen levels compared to invasive methods requiring a blood draw and lab analysis.
- Trial name
- FAST 2024 (NCT06484452)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Malnutrition
Malnutrition Clinical Characteristics Validation and Staffing Optimization Study (MCC Study)
The purpose of this study is to establish the validity of the adult and pediatric Malnutrition Clinical Characteristics (MCC). In addition, this project will: examine the relationship between the MCC and an objective measure of…
- Trial name
- NCT03928548
- Where
- 2 sites in United States
- Volunteers
- 887 people, healthy volunteers welcome
- Sponsor
- Academy of Nutrition and Dietetics
Hypoxia
Accuracy Validation of Belun Oxygen Saturation Pulse Oximeter FDA Submission Study
The purpose of this study is to evaluate the oxygen saturation accuracy performance of Belun Ring Oximeter placed on the index fingers during non-motion conditions
- Trial name
- NCT03439306
- Testing
- Pulse Oximeter
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Belun Technology Company Limited
QTc Evaluation, Electrocardiography
Influence of Moxifloxacin on QTc Interval in Healthy Subjects for Positive Control Validation
The aim of this study is to investigate the effect of moxifloxacin on the QT interval in order to gain information on the validity of results that will be collected during another clinical study testing riociguat in patients with…
- Trial name
- NCT01014247
- Testing
- Avelox (Moxifloxacin, BAY12-8039)
- Where
- 6 sites in Australia, Germany and 2 more
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bayer
Visceral Leishmaniasis
Leishmania Antigen Rapid Diagnostic Test Proof-of-Concept and Validation Study
Visceral leishmaniasis (VL) or kala azar is a neglected tropical disease(NTD) caused by protozoan parasites of the Leishmania donovani complex that are transmitted by phlebotomine sand flies.
- Trial name
- NCT06118749
- Testing
- Antigen detection Rapid Diagnostic Test prototype
- Where
- Kenya
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Pregnancy Related, Pre-Eclampsia
CONNEQT Pulse Validation Study
The purpose of this study is to validate the accuracy of the CONNEQT Pulse blood pressure monitoring system for the measurement of blood pressure as compared to a gold standard, auscultatory sphygmomanometer in a pregnant…
- Conditions
- Pregnancy Related, Pre-Eclampsia, Gestational Hypertension
- Trial name
- NCT06002971
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Colorectal Neoplasms, Digestive System Diseases
Exact CRC Screening Test: Stool Sample Collection Study to Support Assay Validation Testing
The objective of this study is to confirm the sensitivity and specificity of a stool DNA test for detection of colorectal cancer and pre-cancer.
- Conditions
- Colorectal Neoplasms, Digestive System Diseases, Colonic Diseases, Colorectal Cancer
- Trial name
- NCT01600209
- Where
- 13 sites in United States
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Energy Expenditure
MOTIONPOD (TM) Validation and Calibration Study
In this study we propose 1) to develop a new multisensor monitoring system associating a tri-axial accelerometer and a magnetometer to measure physical activity in free-living adults, 2) to perform its calibration and assess its…
- Trial name
- MOTIONPOD(TM) (NCT01317732)
- Testing
- MOTIONPOD (TM) measures
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cardiac Disease
Human Factors Study of Ultrasound Navigation Software for Cardiac Imaging
The Product is a machine learning software, that utilizes AI to provide real-time guidance to acquire diagnostic-quality ultrasound views of the heart.
- Trial name
- NCT05660044
- Where
- Israel
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- UltraSight
Schizophrenia
Transcranial Sonography and Machine Learning for Schizophrenia Identification
Schizophrenia is a serious mental illness. Doctors usually diagnose schizophrenia by talking with patients, reviewing symptoms, and using clinical assessment. In early or less typical cases, diagnosis may be difficult.
- Trial name
- TCS-ML-SZ (NCT07604129)
- Testing
- Transcranial Sonography
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Taizhou Second People's Hospital
Sports Injury
The Turkish Version of the OSTRC Questionnaires
Exposure to repetitive activities and heavy workloads makes athletes vulnerable to overuse injuries over time. Well-timed detection of these injuries is crucial to maintaining their sports career healthily.
- Trial name
- NCT05356065
- Testing
- survey administration
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gazi University
Geriatric, Technology
Turkish Version of Mobile Device Proficiency Questionnaire
The Mobile Device Proficiency Questionnaire (MDPQ) contains 46 questions with eight subscales, which are as follows: mobile device basics, communication, data and file storage, internet, calendar, entertainment, privacy, and…
- Trial name
- NCT06794437
- Testing
- Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Uludag University
Respiratory Rate
Respiratory Rate Validation Study - ChroniSense Polso
20 volunteer test subjects entered into an accuracy study that is designed to validate accuracy of the respiratory rate of the ChroniSense Polso
- Trial name
- NCT05246358
- Testing
- ChoniSense Polso
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ChroniSense Medical Ltd.
Trauma, Psychological, Depression, Anxiety
Validation of a Dance as Therapy Program in Co-facilitation
The objective is to validate a psychotherapeutic group protocol of dance as therapy created by LOBA association with a comparative non-randomized study.
- Conditions
- Trauma, Psychological, Depression, Anxiety, Stress, Body Image
- Trial name
- VaDDanC (NCT06027658)
- Testing
- RECREATION therapy
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Infertility, ART
Automation of the In Vitro Fertilization Laboratory
Enrolled patients will undergo an Assisted Reproductive technology (ART) treatment using intracytoplasmic sperm injection (ICSI, the direct injection of a single sperm cell into an oocyte) as the method of insemination.
- Trial name
- NCT06581068
- Testing
- AURA assisted ART treatment
- Where
- 2 sites in Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Conceivable Life Sciences
Pulmonary Hypertension
Exhaled Breath Olfactory Signature of Pulmonary Arterial Hypertension
In this prospective case-control study, the investigators will evaluate the diagnostic performance of a novel electronic nose (E-nose) for the detection of Pulmonary Arterial Hypertension (PAH). This study is designed to: 1.
- Trial name
- SNOOPY2 (NCT02782026)
- Testing
- Exhaled Breath Olfactory Signature (Artificial Nose)
- Where
- France
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Substance Use Disorder
The Tobacco, Alcohol, Prescription Medication and Other Substances Tool
The purpose of the study is to develop and validate a questionnaire to screen and assess adult primary care patients for tobacco, alcohol, prescription drug, and drug use and problems related to their use.
- Trial name
- CTN0059 (NCT02110693)
- Testing
- Interviewer and tablet administration of the TAPS Tool
- Where
- 4 sites in United States
- Volunteers
- 2,057 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Contraception
Desogestrel-containing COCP Pharmacokinetic Validation Study
This study aims to validate prior pharmacokinetic research with combined oral contraceptive pill users that supports utilizing a 24-hour trough concentration as an accurate proxy for the intensive pharmacokinetic parameter of…
- Trial name
- NCT05002738
- Testing
- Desogestrel and Ethinyl Estradiol Tablets
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alzheimer Disease, Subjective Cognitive Decline
German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)
The SCD-Q (Subjective Cognitive Decline-Questionnaire) is an established instrument to quantify self-perceived cognitive decline. Both self- and informant-rated versions of the SCD-Q are available.
- Trial name
- NCT06711952
- Testing
- Subjective Cognitive Decline-Questionnaire (SCD-Q), Cognitive Failure Questionnaire (CFQ), biomarkers
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich