Clinical trials: Validation Studies
Motor Activity
Validating Accelerometers to Study Physical Activity of Toddlers
One way to assess impacts of nutrition supplements to health is to measure physical activity. Physical activity can be measured with small devices called "accelerometers".
- Trial name
- NCT01188044
- Where
- Malawi
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tampere University
Myocardial Injury, Non-cardiac Surgery
Hemodynamics and Myocardial Injury After Non-cardiac Surgery
The incidence of myocardial injury after non-cardiac surgery (MINS) is approximately 12-15% and is associated with an increased risk of 30-day mortality, 1-year mortality, and 2-year major vascular events.
- Conditions
- Myocardial Injury, Non-cardiac Surgery, Complication,Postoperative, High-sensitivity Troponin
- Trial name
- MINS (NCT05188001)
- Testing
- Not an Interventional Study
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stroke
Validation Study of SCALA, Scale for Lateropulsion
Development and clinical validation of SCALA, a new rating scale for lateropulsion after stroke. A monocentric clinical study including 78 post-stroke individuals and 30 patients without stroke and/or healthy volunteers.
- Trial name
- SCALA (NCT03077399)
- Testing
- SCALA
- Where
- France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Test-Retest Reliability
Validity and Reliability Study of the Motor Accuracy Test
The Motor Accuracy-Revised Test's validity and reliability in Turkey was studied in this paper.
- Trial name
- VRMAT (NCT03781180)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Gambling, Pathological
Screening for Excessive Gambling Behaviors on the Internet
The Internet medium is particularly vector for gambling problems. Since the opening of the online gambling sector in France, no screening for excessive gambling behaviours is provided for by the law, although it is known that…
- Trial name
- EDEIN (NCT02415296)
- Testing
- stage 1, stage 2, stage 3
- Where
- France
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Determine Validity of Concept of Using Hemoglobin Dilution to Assess/Measure Blood Volume.
Calculating Blood Volume by Dilution of Hemoglobin - Pilot Study
Although blood volume is such an important parameter in everyday clinical medicine it cannot be measured easily. As a matter of fact, it is almost never measured but estimated or calculated based upon numbers derived from mostly…
- Trial name
- NCT01900769
- Testing
- Blood Volume Dilution
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kai Schoenhage
Depression, Insomnia
Preliminary Study on the Development and Reliability and Validity of Attention Rating Scale
This study, based on preliminary experimental results, literature review, and expert consultations, developed the Attentional Rating Scale (ARS).
- Conditions
- Depression, Insomnia, Attention Disturbances, Healthy
- Trial name
- NCT06207279
- Testing
- rating
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Endometriosis
Multicenter Study for Diagnostic Validation of a Laboratory Test for the Diagnosis of Endometriosis
Endometriosis affects at least 1 in 10 women worldwide and is associated with a diagnostic delay of 5-10 years. Currently, definitive diagnosis requires invasive laparoscopy, which is costly and burdensome for patients.
- Trial name
- NCT07553676
- Where
- 8 sites in Austria, Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Diamens FlexCo
Healthy Subjects
Definition and Validation of Normative Data of EndoFLIP™ Measurements in Healthy Subjects
Multicenter, Prospective, Non-Randomized clinical trial to define and validate normative data of EGJ-distensibility measurements and contractile patterns in healthy subjects.
- Trial name
- RUBY (NCT03831724)
- Testing
- EndoFLIP™ System with FLIP Topography Module
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Healthy, Arrhythmia
Prospective Study to Validate the Clinical Accuracy of the Norbert Device to Measure Pulse Rate
The study will evaluate the mean average error (MAE) of measuring pulse rate using the Norbert Device (ND) as compared to a reference heart rate measured using an electrocardiogram (ECG).
- Trial name
- NCT05640323
- Testing
- Norbert Device
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Norbert Health
Emergencies, Cardiovascular Diseases
Ultrasound Evaluation of the Jugular Venous Pulse (US-JVP)
The jugular venous pulse (JVP) reflects changes in the right atrial pressure and its evaluation can be useful in managing many emergency conditions for guiding the fluid administration as well as in the diagnosis and/or prognosis…
- Conditions
- Emergencies, Cardiovascular Diseases, Neurovascular Disorders
- Trial name
- US-JVP (NCT03917368)
- Testing
- Ultrasound scan of the internal jugular veins
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- S. Anna Hospital
Ultrasound Imaging of Anatomical Structures
A Volunteer Study to Collect Imaging Data for the Development and Validation of ScanNav Anatomy PNB
This is a single-centre, prospective, non-randomised volunteer study to be undertaken in Intelligent Ultrasound's offices at Hodge House, 114-116 St Mary Street, Cardiff, CF10 1DY, UK.
- Trial name
- NCT04830891
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IntelligentUltrasound Limited
Lung Disease
A Clinical Study Aiming to Validate the Equipment: VoluSense Pediatrics (VSP)
This is a cross-sectional observational study, aiming to validate the accuracy of tidal breathing measurements in infants made by VoluSense Pediatrics, a lung function method based on electromagnetic inductance plethysmography…
- Trial name
- NCT02699268
- Testing
- Lung function measurement
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Biliary Atresia, Neonatal Cholestasis
Development and Validation of a Screening Score for the Biliary Atresia in Infantile Cholestasis: A Prospective Study
Better survival and prognosis of biliary atresia (BA) depend on early diagnosis and timely Kasai portoenterostomy. Identifying BA from other causes of infantile cholestasis at early stage of the disease still remains a major…
- Conditions
- Biliary Atresia, Neonatal Cholestasis, Infantile Hepatitis Syndrome
- Trial name
- NCT03842150
- Testing
- biliary atresia screen score
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Retinitis Pigmentosa, Retinal Dystrophy
Observational Study to Assess the Reliability and Validity of the MLYMT and MLSDT
This is a prospective Multi-Center Observational Study to assess the reliability and validity of the Multi-Luminance Y-Mobility Test (MLYMT) and Multi-Luminance Shape Discrimination Study (MLSDT) Main Outcome Measures: (i)…
- Trial name
- NCT05820100
- Testing
- Observational
- Where
- 8 sites in United States, Puerto Rico
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Nanoscope Therapeutics Inc.
Healthy Adults
Validation of NAD+ Measurements for Human Clinical Studies
The purpose of this study is to determine nicotinamide adenine dinucleotide (NAD) levels in healthy adult subjects before and after supplementing with over-the counter nicotinamide riboside (NR) using magnetic resonance…
- Trial name
- NCT07416786
- Testing
- Oral NR Supplementation
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Validation Study
The Sunrise SpO2 and Pulse Rate Accuracy Validation Study
The purpose of this study is to evaluate the SpO2 accuracy performance of the Sunrise Sensor 2 placed at the tip of the chin during non-motion conditions over the range of 70-100% by comparison to SaO2 values determined from…
- Trial name
- S2-SOPRAV (NCT05386836)
- Testing
- Pulse oximeter validation population
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunrise
Pelvic Organ Prolapse
Validation of Transvaginal Tactile Imaging
The purpose of this study is to validate safety and effectiveness in assessment of the female pelvic floor tissue, and, assess the ability of Vaginal Tactile Imager (VTI) to detect early prolapse conditions and characterize the…
- Trial name
- VTI-03 (NCT01491334)
- Where
- 2 sites in United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Artann Laboratories
Gynecologic Cancer
PERformance of Multi-Cancer Early-detectIon Based on Various Biomarkers in fEmale Cancers, PERCEIVE-II
This study is a prospective study aimed to validate the performance of combined multi-omitcs assays for early detection of gynecologic cancers.
- Trial name
- NCT06001099
- Where
- China
- Volunteers
- 2,935 people, healthy volunteers welcome
- Sponsor
- Fudan University
Suicide Prevention
Validation and Testing of a Suicide Prevention Program to Improve Mental Well-Being Among Adolescents in Gilgit Baltistan, Pakistan: A Pre/Post-Intervention Protocol
Background Globally, around 800,000 people die annually by committing suicide with a disproportionate burden of 77% of these deaths occurring in low- and middle income countries.
- Trial name
- Protocol (NCT06721364)
- Testing
- Suicide prevention treatment
- Where
- Pakistan
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Aga Khan University