Clinical trials: Vaping
Vaping
Point-of-Care Ultrasound (POCUS) Findings and Impact on Vaping
Vaping has emerged as a prominent public health crisis in recent years. In 2023, the National Youth Tobacco Survey found that more than 2.1 million adolescents endorse vaping, with 25% of those endorsing daily use.
- Trial name
- NCT06335329
- Testing
- Discussion of point-of-care ultrasound lung findings
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
E Cigarette Use
A Behavioral Circuit Breathing Training Intervention on Smoking Cessation and Respiratory Function Among Youth Who Use E-cigarettes
This study aims to evaluate the effects of a six-week behavioral circuit breathing training intervention on smoking cessation and respiratory function compared with diaphragmatic breathing training and usual daily activities
- Trial name
- NCT07882407
- Testing
- Circuit Breathing Intervention, Diaphragmatic Breathing
- Where
- Thailand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Second Hand Tobacco Smoke
Impact of Secondhand Exposure to E-cigarettes Aerosols on the Respiratory System
Limited studies have evaluated potential exposure to secondhand e-cigarette aerosol, an indication of impact on indoor air quality.
- Trial name
- TackSHSWP6 (NCT03102684)
- Testing
- Secondhand exposure to e-cigarette aerosols (low), Secondhand exposure to e-cigarette aerosols (high)
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Healthy
Acute Cardiorespiratory Effects of E-cigarette Inhalation
According to the World Health Organization cigarette smoking is today one of the leading single causes of preventable death and morbidity.
- Trial name
- NCT02899234
- Testing
- E-cigarette
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Umeå University
Depressive Symptoms, Depression
Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents
The purpose of this study is to evaluate a mobile application (app) called "Goal2QuitVaping" to help adolescents quit vaping nicotine. Goal2QuitVaping was developed by our research team to assist with quitting vaping.
- Conditions
- Depressive Symptoms, Depression, Adolescent Behavior
- Trial name
- NCT04951193
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Electronic Cigarette Use
Switching Individuals in Treatment for Opioid Use Disorder Who Smoke Cigarettes to the SREC
The goal of this study is to conduct a pilot randomized waitlist-controlled trial to assess the feasibility, acceptability, and preliminary effects of substituting the NIDA standardized research e-cigarette (SREC) for combusted…
- Trial name
- SWITCHED (NCT05881304)
- Testing
- Standardized research e-cigarette (SREC)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tobacco Use Disorder
Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use
In this pilot study, menthol cigarette smokers will be randomized to one of three experimental marketplaces: 1) a condition simulating a ban on menthol cigarettes but not menthol e-cigarettes (condition A); 2) a condition…
- Trial name
- NCT03402243
- Testing
- Menthol ban on cigarettes, Menthol ban on cigarettes and e-cigarettes, No menthol ban
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use
Baby Albert: Electronic Cigarette Pharmacokinetics (PK) and Abuse Liability
The overall aim of the current research is to understand purchasing and product choice behaviors of tobacco/nicotine users if banning the sale of fully nicotinized cigarettes were to go into effect.
- Trial name
- NCT03637452
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
E-Cig Use
The Impact of Chronic E-Cigarette Usage on Microvascular Health
The study is focused on investigating the mechanisms involved in microvascular health in subjects that use e-cigarettes frequently. To explore microvascular health, different techniques and compounds.
- Trial name
- NCT06860698
- Testing
- E-cig use
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Vaping Behavior
High Impact E-cigarette Advertisement Features
This randomized controlled trial aims to examine the effects of high-impact e-cigarette advertisement features among young adults of various tobacco-use statuses.
- Trial name
- NCT06704295
- Testing
- Control ad with dark gray product with tobacco flavor name, Dark gray product with strawberry flavor name, Colorful (strawberry color) product with strawberry flavor name
- Where
- United States
- Volunteers
- 3,083 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Smoking, Vaping
Testing a School-Based E-cigarette, Tobacco, and Betel (Areca) Nut Use Prevention Curriculum for Guam Youths
The people of the U.S. Affiliated Pacific Islands (USAPI) face higher cancer incidence, especially lung/bronchia and head-and-neck cancer, and poorer cancer outcomes, compared with the U.S. nationally.
- Conditions
- Tobacco Smoking, Vaping, Tobacco Chewing
- Trial name
- NCT05037656
- Testing
- School-based curriculum
- Where
- Guam
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- University of Guam
Vaping, Adolescent Behavior
Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens
The investigators long-term goal is to reduce tobacco use and tobacco-related health disparities among SGM populations. The objective of Project SMART (Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender…
- Conditions
- Vaping, Adolescent Behavior, Communication Research
- Trial name
- SMART (NCT06308081)
- Testing
- Tailored
- Where
- United States
- Volunteers
- 1,155 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Nicotine Dependence, Nicotine Vaping
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
In a crossover study, experienced electronic cigarette users will vape 3 different forms of nicotine: natural (derived from tobacco), synthetic, or a 50:50 mixture of both natural and synthetic.
- Trial name
- NCT05962229
- Testing
- (S)-Nicotine, (R)- nicotine, Racemic nicotine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
E-cigarette Use, Microcirculation
The Acute Effects of E-cigarette Inhalation on Vascular Function, Microcirculation and Thrombosis
This is a human randomized controlled cross-over study where the effects of e-cigarette inhalation (with or without nicotine) on vascular function, microcirculation and thrombosis is assessed.
- Conditions
- E-cigarette Use, Microcirculation, Thrombosis, Vascular Function
- Trial name
- NCT04175457
- Testing
- e-cigarette
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Electronic Cigarette Use, Cigarette Smoking
Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 1
This study assess the ways in which e-cigarette product characteristics, such as marketing strategies, impact user experience to inform potential regulations.
- Conditions
- Electronic Cigarette Use, Cigarette Smoking, Cigarette Use, Electronic, Vaping
- Trial name
- NCT05958979
- Testing
- Control Marketing Strategies, Experimental Marketing Strategies
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cervical Dysplasia
Smoking Cessation in Women With Gynecological Conditions
This feasibility study will compare two smoking cessation methods, traditional nicotine replacement therapy and Electronic Nicotine Delivery Systems (electronic cigarettes) in patients with gynecological conditions.
- Trial name
- NCT01989923
- Testing
- Nicotine Replacement Therapy, Electronic Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Smoking
Project 2 Cigarette and E-cigarette Nicotine Content and E-liquid Flavors
Project 2 will evaluate the impact of very low nicotine content cigarettes, e-cigarette nicotine content, and e-cigarette flavoring on cigarettes smoked per day, nicotine exposure, puff topography, discomfort/dysfunction, other…
- Trial name
- NCT03185546
- Testing
- NNC Spectrum Cigarette, VLNC Spectrum Cigarette, Moderate nicotine level e-liquid
- Where
- 2 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
E Cig Use
Young Adult EC Use and Respiratory Outcomes
E-cigarette (EC) use continues to increase among youth, and EC may be detrimental to youth respiratory health. Public health officials and the Food and Drug Administration (FDA) can now regulate ECs.
- Trial name
- NCT04395274
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Smoking, Tobacco Use
Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)
The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. E-cigarettes are classified by the US Food and Drug Administration (FDA) as a tobacco product, though…
- Trial name
- CONNECT (NCT03453385)
- Testing
- Electronic Cigarette
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Electronic Cigarette Use
Assessing Electronic Cigarette Nicotine Flux
The purpose of this study is to determine differences in nicotine delivery, use behavior, carbon monoxide delivery, subjective effects, and physiological effects, when cigarette smokers use an electronic cigarette with constant…
- Trial name
- NCT04378907
- Testing
- Cigarette Smoker/ECIG users: 0 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 6 mg/ml nicotine concentration, Cigarette Smokers/ECIG users: 15 mg/ml nicotine concentration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University