Clinical trials: Variability
Heart Rate Variability
Effects of Arm Crank Versus Treadmill Exercises on Heart Rate Variability in Adult Subjects.
Cardiovascular response to exercise affects the capacity of all body organs depending upon intensity, duration and mode of exercises.
- Trial name
- NCT03068182
- Testing
- Arm crank, Treadmill, Exercise
- Where
- Saudi Arabia
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Obesity
Inter Individual Variation in Weight Loss Response to Exercise
The identification and characterization of individuals who vary in their response to exercise-induced weight loss is important. Weight loss in response to exercise is variable and it remains unknown who will succeed, why, and…
- Trial name
- NCT00773214
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Physiology of Manipulation / Mobilization in Healthy Adults
A Study of the Effects of Mid-Thoracic Spinal Manipulation and Spinal Mobilization on Heart Rate Variability
Spinal mobilization and spinal manipulation are common techniques utilized in the field of physical therapy. Despite their common utility, little is known about the physiological mechanisms underlying the changes experienced…
- Trial name
- NCT02380599
- Testing
- Spinal Manipulation, Spinal Mobilization
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount St. Mary's College, Los Angeles, CA
Healthy, Placebo Effect
Experimental Pain Reporting Accuracy and Placebo Response
Good clinical care relies on precise evaluation of patients' conditions. Chronic pain and other neurological and psychiatric diagnoses pose challenges because their assessment depends on subjective patient-reported outcome…
- Conditions
- Healthy, Placebo Effect, Pain
- Trial name
- NCT03950999
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Motor Activity
Variability of Healthy People and People After Stroke Results in the Nine Hole Peg Test
Main aim of the study is to find out how many attempts of each subtest in the Nine Hole Peg Test should be done in clinical practice during testing people after stroke who are 20-64 years old.
- Trial name
- NCT06395597
- Testing
- Nine Hole Peg Test
- Where
- 2 sites in Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Cardiac Arrest (CA)
Hand vs. Foot Chest Compressions in Simulation
Cardiopulmonary resuscitation (CPR) is essential in the management of cardiorespiratory arrest (CA) to improve survival rates. High-quality chest compressions are the primary intervention to maintain circulation and oxygenation…
- Trial name
- NCT07074080
- Testing
- Performing chest compressions on a mannequin using the foot, Performance of standard chest compressions with the upper limbs.
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
Sympathetic; Imbalance
Comparison of Heart Rate Variability Measurement on the Arm and Chest in Vagus Nerve Stimulation
Healthy participants will be included in this study by invitation and randomised into three groups. Participants in each group will receive bilateral transcutaneous vagus nerve stimulation with the same frequency, current transit…
- Trial name
- NCT07000175
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Overactive Bladder
Evaluation of the Link Between Bladder Sensation and Changes in Skin Electrical Conductance and Heart Rate.
Measuring sympathetic skin response or heart rate variability can provide an objective biomarker of bladder sensation and its modulation by drug with potential to treat overactive bladder.
- Trial name
- NCT00481728
- Testing
- Tolterodine, Filling cystometry, Intravesical neurostimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Healthy Adults
Effects of High-intensity Interval Training and Moderate-intensity Continuous Training on Functioning of Attentional Networks and Heart Rate Variability in Healthy Adults
This study investigated the effects of HIIT and MICT on functioning of attentional networks and explored the relationship between heart rate variability (HRV) and these networks in healthy adults.
- Trial name
- NCT06602700
- Testing
- HIIT, MICT
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Stress, Burn Out
Effects of a Thermal Spa Short Residential Program for Prevention of Work-related Stress / Burn-out on Biomarkers of Stress - A Proof of Concept Study
Work-related stress is a public health issue. Among the multiple physical and psychological consequences of stress, increased mortality and cardiovascular morbidity seem the main concern.
- Conditions
- Stress, Burn Out, Heart Rate Variability
- Trial name
- ThermStress (NCT03536624)
- Testing
- 6 days spa residential program
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetic Cardiovascular Autonomic Neuropathy (DCAN)
Bayesian Estimation of Diagnostic Performance of Diabetic Cardiovascular Autonomic Neuropathy Without a Gold Standard
This study aimed to estimate sensitivities and specificities of diabetic cardiovascular autonomic neuropathy (DCAN) diagnostic tests using the Bayesian approach without a gold standard in another independence dataset.The…
- Trial name
- NCT02461381
- Testing
- not intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Healthy
Validation Study of Selfie Technology for Assessment of Vital Signs
The aim of this study is to compare accuracy of DocMe, a video technology developed by DocMe Health Technologies, with previously validated medical devices used for measurements of heart rate, heart rate variability, respiratory…
- Trial name
- NCT04688112
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- DocMe Technologies Ltd
Heart Rate Variablity
Heart Rate Variability During Sleep After Fast-track Surgery
Based on prior findings concerning sleep disturbances, in particular REM sleep disturbances, after fast-track hip and knee arthroplasty (H-2-2010-011) we performed a supplemental analysis of heart rate variablity after arousals…
- Trial name
- NCT01393236
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lene Krenk
Low Back Pain, Pregnancy
Osteopathic Manipulative Medicine in Pregnancy: Physiologic and Clinical Effects
The purpose of this study is to determine to what extent and by what physiological mechanisms Osteopathic Manipulative Medicine (OMM) affects selected conditions related to pregnancy, labor and delivery.
- Trial name
- NCT00426244
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Anxiety, Cognitive Deficit
Evaluating the Efficacy of Cranial Electrotherapy Stimulation in Mitigating Anxiety-induced Cognitive Deficits
This study investigates the potential of cranial electrotherapy stimulation to mitigate anxiety induced cognitive deficits
- Trial name
- NCT04961112
- Testing
- Cranial Electrotherapy Stimulation
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Tufts University
Healthy Volunteers
Variability of Sulfotransferase 1A1 Activity in Humans: an Approach to Improve Predictive Drug Response - Part I: Analysis of Intraindividual Variation in Healthy Adults
An open-label, single centre, nonrandomized clinical study in healthy volunteers, with intervention over a 13---week period. After written informed consent, subjects will undergo screening evaluations (Visit 1).
- Trial name
- NCT03182595
- Testing
- Paracetamol
- Where
- Portugal
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital da Luz, Portugal
Water Stress, Body Water Dehydration
Influence of Osmotic Stimulation of Vasopressin on Autonomic Function
The regulation of total body water that defines human hydration status is a complex and dynamic process. Current methods of assessing hydration status (e.g.
- Trial name
- NCT04233606
- Testing
- Hypertonic Saline, Normal Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Type-1 Diabetes
Search for a Link Between the Different Variables for Glycaemia and Oxidative Stress or Impaired HDL Function
As glycaemic variability on the one hand and hypoglycaemia on the other are associated with oxidative stress and inflammation, they are likely, in type-1 diabetic patients, to affect the oxidation of lipoproteins and HDL…
- Trial name
- Holter Gly (NCT02862860)
- Testing
- blood sample, urine sample, installation of Holter
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Wrinkle Test
Inter-observer and Intra-observer Variability of the Wrinkle Test
Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation. It is abolished by lesions affecting both central and peripheral sympathetic pathways.
- Trial name
- NCT03813758
- Testing
- wrinkle test
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel