Clinical trials: Variability
Healthy
The Effects of Manual Lymphatic Drainage on the Autonomic Nerve System
Forty healthy women who met the inclusion criteria were included in the study. In the single-blind randomized controlled study, the participants were divided into 3 groups manual lymphatic drainage(MLD), sham MLD, and control…
- Trial name
- NCT05809726
- Testing
- Manual lymph drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Appetitive Behavior
Appetite Variability
This study will examine appetitive sensation variability and the relationship between appetitive sensations and energy intake. Investigators believe the methods for assessing and interpretation of appetitive sensations are…
- Trial name
- NCT04836416
- Testing
- Observational
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Purdue University
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7)
NOTE: This is the sixth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919163
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
T1DM, Sleep Disorders, Circadian Rhythm
Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes
Type 1 diabetes mellitus (T1DM), makes its appearance during childhood and youth, but management implications last till late adulthood.
- Conditions
- T1DM, Sleep Disorders, Circadian Rhythm, ADHD, Memory Impairment
- Trial name
- NCT04054934
- Testing
- Reversed Circadian Rhythm, Normal Circadian Rhythm
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Impaired Blood Glucose Level, Overweight
Early Diagnosis of Diabetes Mellitus Type 2 (DM2)
Rationale: The global prevalence of diabetes, along with its devastating effects on life expectancy and quality of life, continues to increase.
- Conditions
- Impaired Blood Glucose Level, Overweight, Obesity
- Trial name
- 7348 (NCT00469287)
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TNO
Caregiver Burden, Anxiety
Caring Relationships Expression Study
This study will examine a heart rate variability biofeedback (HRVB) intervention versus a music listening control (MLC) for 30 family caregivers (FCGs) of Alzheimer's disease (AD) (and related dementias: ADRD) patients to examine…
- Conditions
- Caregiver Burden, Anxiety, Stress
- Trial name
- CARES (NCT05627687)
- Testing
- Heart Rate Variability Biofeedback, Music Listening Control
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Healthy
Neural Adaptations to a Single Session of Metronome-Paced Strength Training
The aim of the study is to investigate the effects of incorporating variability within a single session of Resistance Training (RT) methods on the neural adaptations along the corticospinal tract and on neuromuscular function.
- Trial name
- NCT06539650
- Testing
- Fractal Paced, Isochronus Paced, Self Paced
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Healthy Young Adults, Healthy Adult Participants
Foam Rolling and Blood Pressure
Foam rolling (FR) has emerged as a widely adopted modality among rehabilitation practitioners and physically active populations.
- Conditions
- Healthy Young Adults, Healthy Adult Participants, Healthy Participants, Normotensive
- Trial name
- NCT07520474
- Testing
- Foam Rolling Intervention (FR)
- Where
- Italy
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Thermogenesis by Different-dosage Mustard Flour Footbaths
Dose-response Relationship of Mustard Flour Footbaths in Healthy Volunteers
A study to explore whether different dosages of mustard flour in footbaths cause different effects on warmth development as well as on general well-being and the autonomic nervous system.
- Trial name
- NCT04321720
- Testing
- 3-g mustard footbath, 6-g mustard footbath, 12-g mustard footbath
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Healthy Subject, Heart Rate Variability
Osteopathic Manipulative Treatment Effects on High Frequency Parameters in Healthy Subjects
The aim of the present study is to determine the extend to which osteopathic manipulative treatment (OMT) is effective on a sample of healthy subjects in changing high frequency (HF) parameters.
- Trial name
- NCT01908920
- Testing
- Osteopathic manipulative treatment, CONTROL
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Stress Physiology
Magnesium Supplementation in Stress Conditions
This study aims to determine how a 6-week magnesium supplementation with 400 mg magnesium from magnesium citrate/magnesium oxide affects stress parameters in students in exam preparation.
- Trial name
- NCT03203096
- Testing
- Magnesium
- Where
- Slovakia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Protina Pharmazeutische GmbH
Healthy
Low-carbohydrate Diet and Low-Density Lipoprotein - Cholesterol (LDL-c) Interindividual Variability
Ketogenic diets are very low-carbohydrate diets that increase hepatic production of ketone bodies, which have several effects as substrates and signals.
- Trial name
- REPETO (NCT07675603)
- Testing
- control diet, Low carbohydrate diet
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bath
Inflammatory Bowel Diseases
Remote Physiologic Monitoring to Detect Inflammatory Bowel Disease (IBD) Flares: A Feasibility Study
Inflammatory bowel disease (IBD) has become a more prominent disease in the US population, with more than 3 million adults in the US affected.
- Trial name
- NCT04333810
- Testing
- Whoop strap 3.0
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hydration
Autonomic Adaptations to Hydration and Brain Functioning
The influence of relatively small decreases in hydration status have been little studied. On two occasions subjects will be allowed to lose about 0,5% of their body weight and one occasion 300ml of water will be consumed.
- Trial name
- NCT03525470
- Testing
- Water, No drink
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Swansea University
Substance-Related Disorders
Resonance Breathing Intervention Opioid Use Disorder
This study aims to assess the feasibility of an intervention for the management of craving, stress, anxiety, and depression among people who use opioids via a resonance breathing smartphone app.
- Trial name
- NCT05830773
- Testing
- Resonance Breathing Exercises
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Cardiovascular Health During Prolonged Sitting
Effect of Chocolate Consumption Prior to Prolonged Sitting on Cardiovascular Health in Young Women
This randomized controlled crossover trial investigates the acute effects of consuming dark, milk, and white chocolate before prolonged sitting on cardiovascular health in healthy young women .
- Trial name
- CHOC-SIT (NCT07556627)
- Testing
- dark chocolate, Milk Chocolate, White Chocolate
- Where
- Saudi Arabia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- King Saud University
Depression
Depression, Trauma, and Health: Efficacy of an mHealth App for Symptom Self-Management in College Students
The study is designed to examine the efficacy of a mobile application heart rate variability biofeedback exercise on heart rate variability and depression.
- Trial name
- DepTH (NCT04094792)
- Testing
- Happify Breather App
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Donna Schuman
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
Healthy
The Effects of Single-Pulse Transcranial Magnetic Stimulation on the Autonomic Nervous System in Healthy Adults
The purpose of this study is to determine the effects of TMS on the ANS. The investigator will determine whether single-pulse TMS of the primary motor cortex in the dominant hemisphere in healthy, young adults will affect 1)…
- Trial name
- NCT02833220
- Testing
- Single-Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Autonomic Nervous System Disease, Osteopathy
Effect of CV4 and Rib Raising Techniques on Autonomic Balance
Background. Heart rate variability (HRV) and skin conductance (SC) highlight autonomic activity and the balance of autonomic nervous system (ANS) which regulates involuntary physiological functions.
- Trial name
- NCT03142373
- Testing
- CV4 technique, RR technique
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS