Clinical trials: Variability
Stress, Acute Stress
Neurophysiological and Autonomic Responses to Acute Physical and Emotional Stress: An EEG Study
This study aims to investigate neurophysiological, autonomic, and subjective responses to different acute physical and emotional stress-inducing conditions using a within-subject repeated-measures design.
- Trial name
- NCT07781670
- Testing
- Cold Pressor Test, Negative Autobiographical Memory Recall, Affective Picture-Viewing Task
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Obstructive Sleep Apnea
Effect of Longitudinal Sleep Monitoring on Diagnosis and Treatment Decision in Patients With Suspected Obstructive Sleep Apnea
Obstructive sleep apnea (OSA) is a highly prevalent sleep-disordered breathing disease, caused by recurrent episodes of partial or complete collapse of the upper airway during sleep, resulting in intermittent hypoxia, fragmented…
- Trial name
- ELSA (NCT03819361)
- Testing
- pulse-oximetry
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Malcolm Kohler
Tobacco Smoking
Heart Rate Variability Biofeedback for Smoking Cessation
Open trial of heart rate variability biofeedback as an adjunct to individualized smoking cessation counseling (SCT) plus transdermal nicotine replacement patch (NRT) in smokers with elevated emotional distress.
- Trial name
- HRVB-SCT (NCT03972137)
- Testing
- Cognitive-Behavioral Smoking Cessation, Heart Rate Variability Biofeedback (HRVB), Transdermal Nicotine patch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Poor Peripheral Perfusion
Perfusion Index Variability in Respiratory Distress Syndrome
Perfusion index may vary according to type of surfactant during the treatment of respiratory distress syndrome.
- Trial name
- NCT01852461
- Testing
- Beractant, Poractant alfa
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Dr. Sami Ulus Children's Hospital
Eccentric Exercise, Muscle Damage
Effects of Exercise-Induced Muscle Damage on Neuromuscular Complexity
This study will examine the effects of exercise-induced muscle damage, induced by eccentric exercise, on torque production, muscle oxygenation, and electromyographic activity of the knee extensors in healthy young men.
- Trial name
- EIMD-NMC (NCT07565376)
- Testing
- Isokinetic eccentric exercise
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Hypertension
High-Intensity Interval Versus Moderate-Intensity Continuous Water Based Exercise in Hypertensive Older Individuals
This study will investigate the acute and chronic effects in hemodynamic and autonomic variables to high-intensity interval versus moderate-intensity continuous heated water-based exercise in older individuals with hypertension.
- Trial name
- HExOLD (NCT04126785)
- Testing
- High Intensity Interval Exercise in Heated Water-Based, Continuous Moderate Exercise in Heated Water-Based, Control Group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Stress
Stress, EEG, ECG, and Chiropractic
The Life University Center for Chiropractic Research is conducting a study to better understand the relationship between subjective stress measures and brain patterns during resting state and an auditory oddball task.
- Trial name
- BLI (NCT05245409)
- Testing
- Chiropractic adjustment using an activator
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Life University
Obesity
Factors Associated With Obesity in Adult Women: Respiratory Exchange Ratio, Heart Rate Variation and Body Image
The prevalence of obesity all over the world has increased year by year, and how to effectively prevent and treat obesity has become an important health care issue.
- Trial name
- NCT04029532
- Testing
- Respiratory exchange ratio, Heart rate variability, Body composition
- Where
- Taiwan
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy
Safety and Tolerability of Lu AF95245 in Healthy Young Men
The purpose of this study is to investigate the safety and tolerability of Lu AF95245 and what the body does to Lu AF95245 after swallowing single doses of the drug
- Trial name
- NCT04199585
- Testing
- Lu AF95245, Lu AF95245 14C radiolabelled spiked dosage
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Peripheral Arterial Disease
Exoskeleton Variability Optimization
Exoskeletons, wearable devices that assist with walking, can improve mobility in clinical populations. With exoskeletons, it is crucial to optimize the assistance profile.
- Trial name
- NCT04338815
- Testing
- Exoskeleton Optimization, Endurance Evaluation
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cortical Excitability, Brain Stimulation
Neuroplastic Alterations of the Motor Cortex by Caffeine
Caffeine is a psychostimulant drug. It acts as a competitive antagonist at adenosine receptors, which modulate cortical excitability as well.
- Conditions
- Cortical Excitability, Brain Stimulation, Caffeine
- Trial name
- NCT04011670
- Testing
- 200 mg caffeine tablet, Non-active tablet
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline
Glucose Variability and Cognition in Prediabetes
This study examines the association of variability in glucose values over a 10-day period with cognitive function and AD risk markers among individuals with prediabetes, aged 50 or older.
- Conditions
- Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, PreDiabetes, Aging
- Trial name
- NCT04201600
- Testing
- Continuous Glucose Monitoring System (CGMS)
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Dietetics, Diet, Healthy
The Effects of External Cues Versus Internal Cues Messaging on Heart Rate Variability and Affect
This randomized controlled trial will assess the effects of External Cues focused messaging (i.e., government recommendations of MyPlate) compared to Internal Cues focused messaging (i.e., intuitive eating).
- Conditions
- Dietetics, Diet, Healthy, Nutrition Therapy, Affect
- Trial name
- NCT05309941
- Testing
- Internal Cues Nutrition Messaging, External Cues Nutrition Messaging
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Delaware
PTSD
Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans
This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder…
- Trial name
- HRVB (NCT00625105)
- Testing
- Biofeedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- William Jennings Bryan Dorn VA Medical Center
Binge Drinking
Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control
Conscious attempts to regulate alcohol use are often undermined by automatic attention and arousal processes activated by alcohol cues, as well as by diminished ability to inhibit in-the-moment behaviors.
- Trial name
- NCT05369169
- Testing
- Resonance breathing, Low demand cognitive task
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cognitive Function 1, Social, Competence
Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology
This study aims to compare heart rate variation, cognitive load, and learning outcomes of novel image-based virtual reality with traditional video in learning for otolaryngology.
- Conditions
- Cognitive Function 1, Social, Competence, Heart Rate Fast, Learning, Spatial
- Trial name
- NCT03501641
- Testing
- image-based virtual reality learning, video-based learning
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Stability & Variability of Lipid-derived Molecules in Sweat
Investigating the Stability, Variability and Mechanism of Incorporation of Lipid Mediators Into Eccrine Sweat
The purpose of this study is to see what the differences are in sweat (amount and small molecule content) collected from different sites of the body and by different methods of sweat stimulation.
- Trial name
- NCT02935894
- Testing
- Ibuprofen, Physiological induction of sweating, Pilocarpine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Gait Variability; Elders; Fall; Re-education
Effect of Observation Plus Imagination of Gait on Stride Variability in Young and Older Adults
The aim of study is to examine the combined effect of observation and imagination of gait on stride time variability of stride time among in healthy young and older adults.
- Trial name
- OBI (NCT02120144)
- Testing
- Observation & imagination, Reading
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Heart Rate Variability, Insomnia Chronic
Discussion on Pulse Diagnosis and Heart Rhythm Variability of Patients With Chronic Insomnia
Discuss the objective assessment of patients with insomnia by pulse diagnosis, and measure by subjective questionnaire and physiological instruments.
- Trial name
- NCT05745519
- Testing
- Pittsburgh sleep quality index (PSQI), ANSWatch
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Healthy
Impact of Air Pollution on the Autonomic Nervous System Activity and the Presence of Sleep Apnea in Older Subjects
Impact of air pollution on the autonomic nervous system activity and presence of sleep apnea in older subjects.
- Trial name
- POLLAIR (NCT01042834)
- Testing
- Air pollution study on healthy volunteers.
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne