Clinical trials: Variability
Familial Mediterranean Fever, Autonomic Dysfunction
Investigation of Autonomic Dysfunction in Patients With Familial Mediterranean Fever
Familial Mediterranean Fever (FMF) is the most common inherited autoinflammatory disease affecting 150,000 patients worldwide. Periodic febrile exacerbations, peritonitis, and pleuritis are characteristic disease features.
- Trial name
- NCT05596643
- Testing
- Composite Autonomic Symptom Score-31, r-r interval variability with normal breathing, r-r interval variability with deep breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Glycemic Response
Ethnic Variability in Glycemic and Hunger Satiety Response to Rice in Overweight Adults
Evidence has./ indicated increased risk of type 2 diabetes with white rice consumption in Asian population. It is shown that glycemic response to carbohydrate-containing food may differ in people of different ethnicities.
- Trial name
- NCT05336032
- Testing
- Food (rice)
- Where
- United Arab Emirates
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rashid Centre for Diabetes and Research
Aging
Healthy Aging Through Optimized Exercise
here is enormous variation in how individuals respond to exercise and understanding the factors that drive this variation will guide individualized exercise prescriptions to improve or maintain health into older age.
- Trial name
- HELIOS (NCT07093216)
- Testing
- Exercise
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Healthy
Influence of Manual and Electrical Vagal Stimulation on Autonomic Activity and Other Dysautonomous Symptoms in a Healthy Population.
The objective of this clinical, longitudinal, prospective, randomised (randomised) unmasked study is to analyse whether electrical and manual vagal stimulation produces changes in heart rate variability in a healthy population…
- Trial name
- NCT07660744
- Testing
- Electrical stimulation of the vagus nerve, Manual stimulation of vagus nerve
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Escoles Universitaries Gimbernat
Lipodystrophy
Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management
This study aims to compare the hemodynamic parameters, postoperative plethysmography variability index, the total amount of postoperative intravenous fluid administration needed, and the urine output of two methods of fluid…
- Trial name
- NCT05930106
- Testing
- Intraoperative fluid ratio, Carotid Artery Doppler Peak Velocity Variation
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TJ Plast Advanced Center for Plastic Surgery
Hyperglycemia, Insulin Sensitivity
Investigating Inter-individual Variability in Glycemic and Insulin Responses
This study aims to test the following hypothesis in healthy lean young men: There are differences in glycemic response (GR) and insulin response (IR) between Chinese, Malay and Asian-Indian There are differences in GI values to…
- Trial name
- NCT01804738
- Testing
- Jasmine rice, Parboiled basmati rice
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Noisy Environment
This study aims to examine whether listening to natural sounds in a noisy (traffic) environment compared to traffic noise only impacts behavioural, cognitive, affective, and physiological markers associated with attention…
- Conditions
- Cognitive Fatigue, Mental Fatigue, Heart Rate Variability, Skin Conductance
- Trial name
- EARS (NCT05009784)
- Testing
- Baseline, Fatigue Manipulation, Traffic Sound
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Cardiovascular Diseases, Prevention
Acute Effects of Beet Extract on Autonomic and Cardiovascular Recovery After Exercise
Dietary NO3 is found in high concentrations in green leafy vegetables and beets. Studies weighing the action of NO3 for ergogenic purposes have found metabolic improvement in skeletal muscle during exercise in hypoxia, lowering…
- Trial name
- NCT04094233
- Testing
- Beetroot extract
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
HRV, Psychological Adaptation
Weight Cut Stress: the Hidden Struggle Beyond Fight Day
This study investigated the effects of rapid weight-cutting on stress in elite kickboxers by analyzing Heart Rate Variability (HRV) and subjective stress levels using a Visual Analog Scale (VAS).
- Trial name
- NCT06860204
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Congestive Heart Failure, Chronic Kidney Diseases
Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects
The study will evaluate the within-subject variability of 20mg ER torsemide as compared to 20mg IR torsemide (Demadex) in fully replicate double-crossover trial in healthy volunteers, who are consuming a high-salt diet (300…
- Trial name
- NCT03214874
- Testing
- Demadex 20mg Tablet, ER Torsemide 20mg Tablet
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sarfez Pharmaceuticals, Inc.
Stress
Photobiomodulation, Heart Rate Variability, and Acute Stress
Photobiomodulation (PBM) is a form of light therapy that uses red or near-infrared light to influence biological processes. In prior studies, PBM has been shown to improve various physiological functions, including tissue repair…
- Trial name
- NCT07475858
- Testing
- Vielight Vagus
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Thermogenesis by Different-dosage Ginger Flour Footbaths
Dose-Response Relationship of Ginger Flour Footbaths in Healthy Volunteers
A study to explore whether different dosages of ginger flour in footbaths cause different effects on warmth development as well as on general well-being and the autonomic nervous system.
- Trial name
- NCT04051476
- Testing
- 3-g footbath, 6-g footbath, 12-g footbath
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Vascular Reaction to Medications
Variability in Adrenergic Response
The goal of this project is to determine the genetic factors contributing to interindividual differences in response to physiological and pharmacological vasoconstrictors and vasodilators.
- Trial name
- NCT00838695
- Testing
- Phenylephrine
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Diabetes Mellitus, Type 1
Assess the Impact of Insulclock on Glycemic Variability and Treatment Compliance in Uncontrolled DM1 Patients
Insulclock® is a small electronic device developed to facilitate the optimal administration of insulin. This device works as an add-on module of commercially available insulin pens and monitors the date, time and dose of…
- Trial name
- Segoclock2 (NCT04847778)
- Testing
- Use of Insulclock system, both Insulclock device and Insulclock 360 app., Use of Insulclock system, both Insulclock device and Insulclock app on masked mode.
- Where
- 4 sites in Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital General de Segovia
Exercise
Smartphone-Based Use of Phonocardiography Technique for Estimating Heart Rate and Heart Rate Variability: Performance Study
This study aims to investigate the use of heart sound recordings, or phonocardiograms, recorded with smartphones' built-in microphones and accessory microphones to estimate heart rate (HR) and heart rate variability (HRV).
- Trial name
- NCT06848179
- Testing
- Computer algorithms, Exercise
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 3 of 7)
NOTE: This is the third of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882542
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy
Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength and Heart Rate Variability
Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent.
- Trial name
- NCT06269042
- Testing
- Inspiratory muscle training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Healthy, Healthy Adult
Assessment of Heart Rate Variability HRV During Descent DE From 2850m to Sea Level and During Re-ascent A From Sea Level to 2850m in Healthy Individuals H
To study the effect of relocation from high altitude (Quito Ecuador: 2850m) to sea level and re-ascent from sea level to 2850m on heart rate variability and other hemodynamic parameters in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07801846
- Testing
- Descent and re-ascent (2850m, sea level)
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Stress, Psychological
Comparative Intervention Study of Stress Reduction in Corporate Health Management
Aim of the study is the evaluation of the effects (psychological and physiological) of an hrv-biofeedback training, a mindfulness training and a combination of both training methods for stress reduction.
- Trial name
- NCT02709551
- Testing
- HRV_Bfb, MBI, MBI_HRV_Bfb
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Type 1 Diabetes
Expanding Coverage of Continuous Subcutaneous Insulin Infusion in Pediatric Patients With Diabetes
The purpose of the study is to present evidence based literature and clinical data to the medical directors at Missouri Medicaid to help modify the existing policy regarding insulin pump therapy in pediatric patients with…
- Trial name
- NCT00829062
- Testing
- Continuous glucose glucose sensor- physician ordered
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City