Clinical trials: Vascular
Diabetic Foot Ulcer
Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft
Despite the widespread use of advanced biologics for the treatment of diabetic foot ulcers, data comparing one type of modality to another are scarce.
- Trial name
- NCT01676272
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Solsys Medical LLC
Peripheral Revascularisation
Optimized Heparin Regimen in Vascular Surgery
Hypothesis: Optimal anticoagulation defined as an Activated Clotting Time (ACT) of 300 to 350 seconds obtained by weight-adjusted doses of unfractionated heparin (UFH) will improve the hemostatic environment downstream from the…
- Trial name
- NCT02477072
- Testing
- ACT, TEG, Ankle-brachial index
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Coronary Artery Disease
Statin and Post-interventional Coronary Microcirculation Dysfunction
The purpose of this study is to evaluate the effect of statin on the coronary microcirculation dysfunction measured after percutaneous coronary intervention.
- Trial name
- NCT01751295
- Testing
- Atorvastatin, pre-treatment 80 mg/day for 4 days before PCI
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Samsung Medical Center
Peripheral Vascular Diseases, Percutaneous Intervention Via Femoral Artery
Angio-seal VIP Versus Perclose ProGlide for Closure of the Femoral Artery in Peripheral Vascular Disease
This study is designed to evaluate the efficacy (device deployment characteristics and performance) and safety (adverse access site related events) of Perclose ProGlide (Abbott Vascular Devices) for femoral access site closure in…
- Trial name
- NCT05334095
- Testing
- Perclose ProGlide, Angio-seal VIP
- Where
- China
- Volunteers
- 1,062 people
- Sponsor
- Xiongjing Jiang
Diabetic Foot, Venous Ulcer
Adipose Derived Regenerative Cellular Therapy of Chronic Wounds
Our study aims to explore the effects of Adipose Derived Stem Cells (ASCs) on chronic wounds.
- Conditions
- Diabetic Foot, Venous Ulcer, Pressure Ulcer
- Trial name
- NCT02092870
- Testing
- Adipose derived stem cells
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Tower Outpatient Surgical Center
Ischemic Stroke
A Study of Survival and Outcome After Stroke
The objective of this study is to determine the natural history of acute ischemic stroke from large vessel thromboembolism in the brain.
- Trial name
- SOS (NCT01193569)
- Where
- United Kingdom
- Volunteers
- 142 people
- Sponsor
- Penumbra Inc.
Hypertension, Lipid Metabolism Disorders
Alpha-linolenic Acid and Blood Pressure
Rationale: Increased intakes of n-3 long chain polyunsaturated fatty acids eicosapentanoic acid (EPA) and docosahexaenoic acid (DHA), mainly found in fatty fish, are recommended for the prevention of coronary heart disease.
- Trial name
- VASALA (NCT02243969)
- Testing
- Flaxseed oil, high oleic sunflower oil (HOSF)
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Coronary Heart Disease, Mindfulness
Mindfulness-based Interventions on Psychophysiological Recovery and Physical Functioning After Coronary Heart Surgery
The purpose of this study is to explore the effect of mindfulness on the physical and mental recovery and physical function of patients after coronary heart surgery.
- Conditions
- Coronary Heart Disease, Mindfulness, Recovery, Psychological, Physical Functioning
- Trial name
- NCT06637969
- Testing
- mindfulness-based
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Hemiparesis, Stroke
Walking Therapy In Hemiparetic Stroke Patients Using Robotic-Assisted Treadmill Training
The overall goal of this study is to determine whether robotic-assisted gait training is better than standard physical therapy treatments for improving walking ability in hemiparetic stroke patients.
- Trial name
- NCT00075283
- Testing
- Lokomat (Robotic Orthosis) combined with slat belt treadmill
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- U.S. Department of Education
Chronic Urticaria
Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria
This study looks at changes in cell proteins in people with chronic hives treated with omalizumab.
- Trial name
- NCT01701583
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Hypertension, Hypotension
Accuracy of Non-Invasive Blood Pressure Measurement in Adults
The purpose of this study is to compare the accuracy of the Sotera ViSi, an investigational device, to auscultation (measurement with a cuff) in determining systolic and diastolic blood pressure (BP) in adult subjects.
- Trial name
- NIBP (NCT01183741)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sotera Wireless, Inc.
Multiple Myeloma
Tandem Melphalan and Autolog. SCT in MM Patients 60 to 70 Years of Age With and Without Induction Chemotherapy
Patients 60 to 70 years of age with newly diagnosed multiple myeloma were prospectively randomized between 4 cycles of anthracycline/dexamethasone-based induction chemotherapy (A1) or only 2 x 4 days of dexamethasone (A2).
- Trial name
- DSMM-II (NCT02288741)
- Testing
- Anthracycline/dexamethasone-based induction chemotherapy, Dexamethasone for control of symptoms, Tumor-reduction chemotherapy and stem cell mobilization
- Volunteers
- 549 people
- Sponsor
- WiSP Wissenschaftlicher Service Pharma GmbH
Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage
Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage
The overall aim of this pilot study is to investigate the development of magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) markers after cerebral amyloid angiopathy (CAA)-related and hypertensive arteriopathy…
- Conditions
- Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage, Hypertensive Hemorrhage, Intracranial, Cognitive Decline
- Trial name
- COACH (NCT05499169)
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Leiden University Medical Center
Cardiovascular Diseases, Atherosclerosis
Inflammation Genomics and Atherosclerosis - Ancillary to CARDIA
To examine the associations of common variation in inflammation/thrombosis genes with intermediate quantitative phenotypes and subclinical coronary atherosclerosis in the Coronary Artery Risk Factor Development in Young Adults…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Coronary Arteriosclerosis, Inflammation
- Trial name
- NCT00046605
- Volunteers
- 3,600 people
- Sponsor
- University of Washington
Coronary Artery Disease (CAD)
Prognostic Value of High Dose Dobutamine Stress Magnetic Resonance Imaging
High-dose dobutamine/atropine stress cardiac magnetic resonance imaging (DS-MRI) has been incorporated in daily clinical practice for the detection of ischemic heart disease.
- Trial name
- DS-Prognosis (NCT00837005)
- Where
- Germany
- Volunteers
- 2,500 people
- Sponsor
- Heidelberg University
Peripheral Artery Disease
AMS INSIGHT 1 Study - Bioabsorbable Metal Stent Investigation in Chronic Limb Ischemia Treatment
Prospective, multicenter, randomized clinical trial, Follow-up at 1-, 6- and 12 months This clinical investigation is first of all designed to demonstrate the safety and effectiveness of the MAGIC EXPLORER stent system.
- Trial name
- AMS-INSIGHT1 (NCT00572494)
- Testing
- MAGIC EXPLORER (Biotronik AG), PLEON EXPLORER (Biotronik AG)
- Where
- 12 sites in Austria, Belgium and 2 more
- Volunteers
- 117 people
- Sponsor
- Flanders Medical Research Program
Venous Thromboembolism, Deep Vein Thrombosis
Venous Thrombo-Embolism Imaging Database (VTE-ID)
The purpose of this study is to identify and validate new imaging biomarkers allowing an individual phenotyping of patient with venous thrombo-embolism (VTE), mainly in terms of recurrence risk assessment and to distinguish…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- VTE-ID (NCT06258694)
- Where
- France
- Volunteers
- 2,208 people
- Sponsor
- University Hospital, Brest
Multiple Sclerosis, Stroke
PLasmatic Extracellular Vesicles AS Biomarkers of nEural Tissue Damage
Recently proposed central nervous system damage biomarkers detectable in biofluids, such as neurofilament light chain (NfL) have several limits, including a lack in specificity and a kinetic that does not allow them to be used as…
- Trial name
- PLEASE (NCT07769294)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Roberto Furlan
HIV, Atherosclerosis
ER Niacin/Laropiprant Impact on Cardiovascular Markers and Atheroprogression in HIV-infected Individuals on cART
HIV-infected patients are at increased risk for cardiovascular disease. Large investigations support an inverse correlation between HDL-C levels and coronary heart disease.
- Trial name
- NILACH (NCT01683656)
- Testing
- niacin/laropiprant
- Where
- 7 sites in Switzerland
- Volunteers
- 4 people
- Sponsor
- Calmy Alexandra
Myocardial Infarction
Safety of Early Discharge Following Low Risk Myocardial Infarction
Objectives: The primary objective of this study is to evaluate the safety of an early discharge strategy in patients with low risk ST-elevation myocardial infarction (STEMI), treated with primary percutaneous coronary…
- Trial name
- EDAMI (NCT01868256)
- Testing
- early discharge (<72 h), Conventional discharge
- Where
- Spain
- Volunteers
- 1,558 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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