Clinical trials: Vascular Conditions
End Stage Renal Failure, Hemodialysis, Cannulation
Guided Needle Insertion for Vascular Access
The goal of this clinical trial is to determine whether the study device can assist the cannulator with placing two needles during cannulation required to initiate dialysis treatment.
- Trial name
- ACCESS 2 (NCT07548151)
- Testing
- Ultrasound-Guided, Power-Assisted Needle Insertion
- Where
- Uzbekistan
- Volunteers
- 10 people
- Sponsor
- X9, Inc.
Transient Ischemic Attack
Markers in the Diagnosis of TIA
MIND-TIA is primarily an observational diagnostic study that aims to evaluate the role of novel biomarkers in the diagnosis of Transient Ischemic Attack (TIA)in primary care.
- Trial name
- MIND-TIA (NCT01954329)
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- UMC Utrecht
Pituitary Tumor, Meningioma
Long-Term Longitudinal QoL in Patients Undergoing EEA
This is a prospective longitudinal study to access postoperative 2-year quality of life in patients who undergo endonasal endoscopic approach surgeries of the skull base.
- Conditions
- Pituitary Tumor, Meningioma, Rathke Cleft Cysts, Chordoma
- Trial name
- NCT04087902
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Myocardial Infarction
Abbott i-STAT High Sensitivity Troponin I Study
The goal of this observational multi-center study is to evaluate the clinical performance of the i-STAT hs-TnI test (i-STAT High Sensitivity Troponin I) using the investigational i-STAT hs-TnI cartridge for the proposed intended…
- Trial name
- i-STAT hs-TnI (NCT05629572)
- Testing
- i-STAT hs-TnI Cartridge Testing on i-STAT 1 and i-STAT Alinity
- Where
- 28 sites in United States
- Volunteers
- 3,697 people
- Sponsor
- Abbott Point of Care
Hypertension, Diabetes
Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure
The main objective of the study is to compare the effect of two different types of physical exercise modalities on glycated hemoglobin and blood pressure in elderly individuals with multimorbidity.
- Conditions
- Hypertension, Diabetes, Osteoarthritis, Depression Disorders
- Trial name
- NCT06879639
- Testing
- Exercise, Control
- Where
- Portugal
- Volunteers
- 63 people
- Sponsor
- Universidade do Porto
Pulmonary Hypertension: Efficacy of Rehabilitation
Pulmonary Hypertension: Efficacy of a 3 Week Inpatient Rehabilitation on Physical Condition, Body Composition and Health Related Quality of Life
Pulmonary hypertension (PH) leads to impaired physical condition (PC), body composition (BC) and health-related quality of life (HRQOL).
- Trial name
- NCT01650857
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Muscle Spasticity, Stroke
Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity
This is a multi-center, randomized, double-blind (patient and evaluator), sham-controlled study to be conducted in stroke patients with upper-extremity spasticity.
- Trial name
- RECOVER (NCT04742257)
- Testing
- MyoRegulator® device
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- PathMaker Neurosystems Inc.
Coronary Heart Disease, Unstable Angina
Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina
In this study, typical cases of coronary heart disease are selected. They will be intervened by Xuesaitong soft capsules to investigate efficacy and safety for Coronary Heart disease.
- Trial name
- NCT03083119
- Testing
- Xuesaitong soft capsule
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jie Wang
Stroke, Chronic Stroke
Neural Operant Conditioning
The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT06113965
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
STEMI, No-Reflow Phenomenon
Empagliflozin for No-reflow Phenomenon in PCI for STEMI
Myocardial infarction remains, in our current era, a leading cause of morbidity and mortality both domestically and globally. A significant contributor to this issue is reperfusion injury, which enlarges the infarction…
- Trial name
- EMPA-PCI (NCT06342141)
- Testing
- Empagliflozin 25 milgrams (Mg), Empagliflozin 10 Mg
- Where
- Mexico
- Volunteers
- 162 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Venous Leg Ulcer
HM242-Gel vs Comparator
The primary objective of the study is to demonstrate that the HM242-Gel performs at least comparably to INTRASITE Gel with regard to wound healing.
- Trial name
- NCT04902651
- Testing
- HM242-Gel, Intrasite Gel
- Where
- 3 sites in Czechia, Slovakia
- Volunteers
- 73 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Pulmonary Embolism, Quality of Life and Dyspnea
Impact on Quality of Life With Pulmonary RehAbilitation After Pulmonary eMBOlism: RAMBO Study
Pulmonary Embolism (PE) is a common and serious disease. Indeed, the annual incidence is 1/1000 patients per year and the 3-month mortality is 10%, which is twice that of myocardial infarction.
- Trial name
- RAMBO (NCT05015153)
- Testing
- Pulmonary rehabilitation (PR)
- Where
- 6 sites in France
- Volunteers
- 112 people
- Sponsor
- University Hospital, Brest
Vasospasm, Cerebral, Aneurysmal Subarachnoid Hemorrhage
The Effect of Sympathetic Modulation on Cerebral Vasospasm Secondary to Aneurysmal Subarachnoid Hemorrhage
The purpose of the study is to see that in addition to existing therapy, how well an additional procedure named spinal cord stimulation might reduce blood vessel spasm from aneurysm rupture.
- Trial name
- NCT06443177
- Testing
- Vectris trial leads and stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Sleep Disorders, Intrinsic
Cerebral Hemodynamics in Sleep Disorders
The purpose of this study is to determine the relationship between sleep disorders and cerebral hemodynamics.
- Trial name
- NCT02752139
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Yi Yang
Diabetic Macular Edema, Age-Related Macular Degeneration
Effect of Corona Virus on Intravitreal Injections
During pandemic of corona virus, patients compliance may be affected. We aim to study the factors lead to unregulated visits and its implications on the final visual outcome.
- Conditions
- Diabetic Macular Edema, Age-Related Macular Degeneration, Choroidal Neovascularization, Myopic Choroidal Neovascularisation
- Trial name
- NCT05494775
- Testing
- Anti-vascular endothelial growth factors (Anti-VEGFs)
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Benha University
Acute Myocardial Infarction
Hair Cortisol and Testosterone Levels in Patients With and Without Acute Myocardial Infarction(MI)
The purpose of this study is to determine whether hair levels of cortisol and testosterone are elevated in patients with acute MI compared to controls.
- Trial name
- NCT01144065
- Testing
- Hair sampling for the measurement of cortisol and testosterone
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Meir Medical Center
Vascular Parkinsonism, Drug-induced Parkinsonism
AI-Enhanced Optimization of Acute Levodopa Challenge Test
A quantitative evaluation method was developed for Parkinson's disease and other atypical parkinonism by integrating an innovative motor paradigm with perception technologies and artificial intelligence.
- Conditions
- Vascular Parkinsonism, Drug-induced Parkinsonism, Corticobasal Degeneration (CBD), Parkinson Disease (PD)
- Trial name
- NCT06949865
- Testing
- video recording
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Kidney Transplant Patients
Observational Single-center Study of the Relationship Between Arterial Hypertension and Hypervolemia Defined by Self-measurement of Impedancemetry in Kidney Transplant Patients With Transplantation Less Than 6 Months Old
The working hypothesis is that hypertension during the first post-transplant trimester is partly explained by the patient's hypervolemia.
- Trial name
- HTAôConnect (NCT05039788)
- Testing
- Measurement of systolic and diastolic blood pressure, impedancemetry, weight, creatinemia and Pro-BNP measurements
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Nantes University Hospital
Relapsed or Refractory Multiple Myeloma
Vorinostat (MK-0683, SAHA [Suberoylanilide Hydroxamic Acid]) + Lenalidomide + Dexamethasone in Multiple Myeloma (MM) (MK-0683-074)
The purpose of this Phase I study of vorinostat in combination with lenalidomide and dexamethasone in participants with relapsed or refractory multiple myeloma is to determine the maximum tolerated dose (MTD) as estimated by the…
- Trial name
- NCT00642954
- Testing
- Vorinostat, Lenalidomide, Dexamethasone
- Volunteers
- 31 people
- Sponsor
- Merck Sharp & Dohme LLC
Cerebral Hemorrhage
ITCH Trial: Protocol for a Randomized, Double Blind Placebo-controlled Trial
Intracerebral hemorrhage is increasingly becoming a major burden in the society because of significant morbidity as well as mortality.
- Trial name
- NCT04742205
- Testing
- Tranexamic Acid 500 MG
- Where
- Nepal
- Volunteers
- 154 people
- Sponsor
- Kathmandu Medical College and Teaching Hospital
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