Clinical trials: Vascular Disease Risk
Cardiovascular Diseases, Hypertension
ICA-CHAMP: Indo-Central Asian Cardiovascular Health Assessment and Management Program
Research has shown that the presence of heart disease and stroke is higher in the Indo-Asian population compared to other ethno-cultural groups.
- Conditions
- Cardiovascular Diseases, Hypertension, Hyperlipidemia
- Trial name
- ICA-CHAMP (NCT00627159)
- Testing
- High risk assessment, Low to moderate risk
- Where
- 2 sites in Canada
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Platelet Function Tests, Predictive Value of Tests
Risk Stratification Post TAVI Using TEG
Transcatheter aortic valve implantation (TAVI) has become the standard of care in elderly patients at increased risk for surgical aortic valve replacement . However, the optimal antithrombotic strategy post TAVI is still unclear.
- Conditions
- Platelet Function Tests, Predictive Value of Tests, Thrombelastography, Cardiovascular Diseases
- Trial name
- RISTRATAVI (NCT03649594)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Torben Pottgiesser
Stroke
Beren Vibration Insole in Stroke Rehabilitation
The aim of this study is to investigate the effects of a custom-made vibration insole on gait, balance, and fall risk in patients with stroke.
- Trial name
- NCT07898579
- Testing
- Conventional Physiotherapy, Plantar Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bitlis Eren University
Hypertension
Primary Care Strategies to Reduce High Blood Pressure: A Cluster Randomized Trial in Rural Bangladesh, Pakistan and Sri Lanka
Background: High blood pressure (BP) is the leading attributable risk for cardiovascular disease (CVD). In rural South Asia, hypertension remains to be a significant public health issue with sub-optimal rates of case finding and…
- Trial name
- COBRA-BPS (NCT02657746)
- Testing
- multi-component interventions
- Volunteers
- 2,550 people
- Sponsor
- Duke-NUS Graduate Medical School
Stroke
Comparison of Mirror Therapy and Modified Constrain Induced Movement Therapy on Risk of Fall, Balance and Gait in Stroke
There will be a difference between modified constraint induced movement therapy and Mirror Therapy on lower limb for risk of fall, balance and gait in stroke patients.
- Trial name
- NCT05985603
- Testing
- CIMT Group, Mirror Therapy group
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Open Angle Glaucoma
Progressive Open Angle Glaucoma (OAG) and Ocular Blood Flow
The purpose of this study is to assess the correlation of vascular parameters, including genetic factors as well as ocular blood flow parameters against the progression rate of glaucomatous damage in patients with progressive OAG.
- Trial name
- NCT00912470
- Testing
- ocular blood flow measurement
- Where
- Austria
- Sponsor
- Medical University of Vienna
Myocardial Infarction, Diet
Dietary Antioxidants and Chronic Diseases-The Swedish National March Cohort
Dietary antioxidants might protect from the development of chronic diseases by reducing levels of oxidative stress. The investigators therefore investigated the effect of dietary Non Enzymatic Antioxidant Capacity, which measures…
- Conditions
- Myocardial Infarction, Diet, Osteoarthritis
- Trial name
- NCT03350568
- Testing
- Total dietary NEAC assessed at baseline
- Where
- Sweden
- Volunteers
- 43,880 people
- Sponsor
- Karolinska Institutet
Healthy, Coronary Disease
Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study
Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors.
- Conditions
- Healthy, Coronary Disease, Myocardial Infarction, Cerebral Infarction
- Trial name
- NCT00262691
- Where
- Japan
- Volunteers
- 7,000 people
- Sponsor
- Nagoya University
Peripheral Arterial Disease
Multifactor Risk Reduction for Optimal Management of PAD
Patients with peripheral arterial disease (PAD) experience significant functional limitations due to ischemic symptoms (claudication) and are at high risk for CVD morbidity and mortality resulting from untreated cardiovascular…
- Trial name
- VIGOR2 (NCT00537225)
- Testing
- exercise
- Volunteers
- 300 people
- Sponsor
- Palo Alto Veterans Institute for Research
Stroke, Ischemic
Transitional Care Program to Improve Risk Factors in Stroke Survivors
The goal of this clinical trial is to evaluate whether our transitional care program helps stroke survivors better manage their risk factors for stroke to lower the risk of a repeat stroke.
- Trial name
- NCT06657235
- Testing
- Transitional Care Program
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Syntrillo, Inc
Multiple Myeloma
Pomalidomide in Gene Expression Profiling (GEP)-Defined High-risk Multiple Myeloma
This is a phase II study, open-label, single institution trial of pomalidomide in GEP-defined, high-risk relapsing/refractory multiple myeloma. Prior therapy must have included lenalidomide.
- Trial name
- NCT01177735
- Testing
- Pomalidomide
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Arkansas
Relapsed/Refractory Multiple Myeloma (RRMM)
Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)
This study is researching whether the use of tocilizumab before the first dose of linvoseltamab will decrease the risk of Cytokine Release Syndrome (CRS) in participants who have Relapsed or Refractory Multiple Myeloma (RRMM) who…
- Trial name
- POPLIN (NCT07609940)
- Testing
- Linvoseltamab, Tocilizumab
- Where
- 7 sites in United States
- Volunteers
- 30 people
- Sponsor
- Regeneron Pharmaceuticals
Coronary Artery Disease, Angina Pectoris
Lesional Evaluation of High Risk Patients With Neoatherosclerosis Treated With Rosuvastatin and Eicosapentaenoic Acid Using Optical Coherence Tomography(OCT)[LINK IT TWO]
This study aim is to evaluate the additional effect of eicosapentaenoic acid and dose up effect of rosuvastatin for neoatherosclerosis in coronary artery disease patients.
- Trial name
- NCT03657758
- Testing
- EPA and rosuvastatin, High dose rosuvastatin
- Where
- Japan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kobe University
Hypotension, Pressure Ulcer
Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion
Continuous pulse oximetry monitoring is the standard of care in critically ill patients in emergency departments, operating rooms and intensive care units.
- Trial name
- NCT02382133
- Testing
- Nasal alar oxygen sensor
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Washington University School of Medicine
Pulmonary Embolism
Performance of Pulmonary Embolism Risk Scores Out Come in CTPA Confirmed Patients
1. Assess performance of PERFORM score in predicting outcome in CTPA confirmed patients. 2. Compare PERFORM score with the currently validated PESI in risk stratification of patients
- Trial name
- NCT05613855
- Volunteers
- 60 people
- Sponsor
- Assiut University
Stroke, Ischemic
Validation of TriAGE+ for Predicting Stroke Risk in ED Patients Presenting With Dizziness
Ischemic cerebrovascular diseases originating from the brain's posterior circulation account for 20-25% of cases. Among patients diagnosed with cerebellar infarction, 10% present with isolated dizziness as their sole symptom.
- Trial name
- NCT06641050
- Testing
- TRIAGE+ score assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 818 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Ovarian Hyperstimulation Syndrome, Cardiovascular Diseases
Medical Assistance for the Procreation and Risk of Thrombosis.
This study aims at evaluating clincal practice regarding prevention of arterial and venous thrombosis following ovarian stimulation.
- Conditions
- Ovarian Hyperstimulation Syndrome, Cardiovascular Diseases, Embolism and Thrombosis
- Trial name
- AMPERT (NCT02610608)
- Testing
- ovarian stimulation
- Where
- 9 sites in France
- Volunteers
- 129 people
- Sponsor
- University Hospital, Brest
Diabetic Patients With/Without Atherosclerotic Diseases
Cardiovascular Risk Assesment in Diabetic Patients Via Lens Autofluorecscence Detection
The rate of lens autofluorescence will be compared in diabetic and non diabetic patients with/without atherosclerotic vascular diseases to evaluate if it is associated with the risk of cardiovascular diseases.
- Trial name
- CRADILA (NCT02947555)
- Testing
- Non interventional
- Where
- Hungary
- Volunteers
- 420 people
- Sponsor
- Dr. Gergő Molnár
Myocardial Ischemia, Rheumatic Diseases
Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications
Ischemic heart disease (IHD) and its treatment carry profound public health and economic implications. Among Veterans, IHD represents one of the most common causes of death and disability, with over 500,000 affected individuals'…
- Trial name
- SEPPRMACI-ARM (NCT02694185)
- Testing
- Caplan IVR
- Where
- 5 sites in United States, Puerto Rico
- Volunteers
- 5,269 people
- Sponsor
- VA Office of Research and Development
Stroke, Ischemic
Prognostic Factors and Mortality in Older Stroke Patients With Mechanical Thrombectomy
The study focus on the elderly patient (older than 80 years of age) who had acute ischemic stroke and received mechanical thrombectomy.
- Trial name
- NCT04672148
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Far Eastern Memorial Hospital
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