Clinical trials: Vascular Insufficiency
Varicose Veins
An Open-label, Single-dose Pilot Study to Evaluate Varisolve® (Polidocanol Endovenous Microfoam (PEM)) 0.125% [0.2%] for Varicose Veins
To determine the effect and safety of Varisolve® 0.125% [0.2%]
- Trial name
- NCT00928421
- Testing
- Polidocanol Endovenous Microfoam 0.125%
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Boston Scientific Corporation
Respiratory Impairment, Elevated Blood Pressure
Walking and Blood Pressure in Older Adults With Respiratory Impairment.
The purpose of this study is to evaluate the effect of an 8-week walking program on blood pressure in inactive older adults with respiratory impairment, a condition where lung function is sub-optimal for a person's age.
- Conditions
- Respiratory Impairment, Elevated Blood Pressure, Physical Inactivity
- Trial name
- NCT06033417
- Testing
- Increased lifestyle walking (intervention), Health education only (control)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Iowa State University
Pulmonary Hypertension, Chronic Kidney Disease
Invasive and Non-invasive Haemodynamic Assessment of Pulmonary Hypertension in Chronic Kidney Disease Patient
Patients with CKD who suspected to have pulmonary hypertension by echocardiography with high probability, RHC used to confirm the diagnosis, assessment of hemodynamic parameters, differentiate pre and post capillary types of…
- Trial name
- NCT07052968
- Testing
- Echocardiography
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Coronary Syndrome
Prognosis of Patients With Acute Coronary Syndrome Complicated With Renal Insufficiency(PACS-RI)
Several epidemiologic studies reported that patients with renal insufficiency might have increased cardiovascular disease-related mortality rates after Percutaneous coronary intervention (PCI) .
- Trial name
- PACS-RI (NCT03044990)
- Where
- China
- Volunteers
- 2,014 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Renal Failure, Cardiovascular Diseases
Pilot Medical Evaluation of the T50 Test
This pilot study aims to evaluate in an exploratory way the predictive power of a novel in vitro test (T50 Calcification Inhibition Test, T50 CIT), which measures the mineralization inhibition capacity of blood, in terms of its…
- Conditions
- Renal Failure, Cardiovascular Diseases, Vascular Calcification
- Trial name
- NCT03292029
- Testing
- T50 Calcification Inhibition Test (CIT)
- Where
- 8 sites in Spain
- Volunteers
- 776 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Post-thrombotic Syndrome, May-Thurner Syndrome
Treadmill Pilot Study (Invasive Pressure Measurements in PTS)
Patients with unilateral post-thrombotic obstruction of the iliac tract and or common femoral vein, eligible for stenting are included. Intravenous pressure is measured in both dorsal foot veins and both common femoral veins.
- Trial name
- NCT01846780
- Testing
- PTA & stenting
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Diseases, Heart Diseases
Fifteen Year Follow-up of 5,500 Black and 5,500 Other Hypertensives
To seek predictors of mortality, hospitalization, and dialysis using data from a hypertensive population which began treatment in 1974.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Kidney Failure, Chronic
- Trial name
- NCT00005417
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Mitral Valve Insufficiency, Coronary Artery Disease
Long Term Follow Up for CTSN Mitral Valve Repair Studies
This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about…
- Trial name
- NCT03066050
- Testing
- MV Repair, MV Replacement, CABG
- Where
- 24 sites in United States, Canada
- Volunteers
- 368 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Venous Disease, Chronic Venous Insufficiency, CVI
The ReCAna for Lower ExtremIty Venous OBstructions and In-StEnt Restenosis Registry
The goal of this observational study is to gather additional safety and performance (effectiveness) data on the device for the treatment of symptomatic lower extremity venous obstructions and occlusions.
- Conditions
- Chronic Venous Disease, Chronic Venous Insufficiency, CVI, Venous Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- CALIBER (NCT07529756)
- Testing
- Recanalization and debulking
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Intervene, Inc.
Venous Insufficiency
The Effects of Compression Stockings on Pressure Parameters in Patients With Chronic Venous Insufficiency
The main objective of this study is to obtain data to determine, in each individual with and without wearing compression stockings of different strengths and during different postures, the relationship between interface pressure…
- Trial name
- MACIVC (NCT01558024)
- Testing
- Intravenous pressure and intramuscular pressure measurement
- Where
- 2 sites in France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Venous Thromboembolism, Blood Clot
Statins for Venous Event Reduction in Patients With Venous Thromboembolism
The standard or usual treatment for patients diagnosed with deep vein thrombosis or pulmonary embolism is treatment with blood thinners (called anticoagulants).
- Conditions
- Venous Thromboembolism, Blood Clot, Post Thrombotic Syndrome
- Trial name
- SAVER (NCT04319627)
- Testing
- Rosuvastatin Calcium
- Where
- 31 sites in Canada, France and 4 more
- Volunteers
- 2,700 people
- Sponsor
- Ottawa Hospital Research Institute
Acute Kidney Injury (Nontraumatic), Coronary Artery Disease
Contrast RISK (Reducing Injury Sustained by Kidneys)
Diagnostic and therapeutic cardiac catheterization procedures are important interventions to reduce the risk of death, avoid future cardiovascular events, and improve quality of life of people with heart disease.
- Trial name
- Contrast RISK (NCT03453996)
- Testing
- Intervention, Control
- Where
- 3 sites in Canada
- Volunteers
- 7,280 people
- Sponsor
- University of Calgary
Kidney Failure
To Assess Ear Blood Flow During Dialysis
This is a prospective observational pilot study of patients under the care of the Royal Free Hospital with chronic kidney disease who have been established on regular thrice weekly haemodialysis treatments in a dialysis centre,to…
- Trial name
- NCT02545920
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Bone Diseases, Metabolic Syndrome X
Effect of Exercise and Phytoestrogen on Bone, Metabolic Syndrome Criteria and Complaints of the Early Menopause
The aim of the study is to compare the effect of a progressive, periodized exercise training designed to impact bone, CHD-risk-factors and menopausal complaints versus the combined effect of exercise and "phytoestrogen"…
- Conditions
- Bone Diseases, Metabolic Syndrome X, Coronary Disease
- Trial name
- NCT00663104
- Testing
- exercise, exercise + cimicifuga racemosa
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Hypotension, Brain Injuries
Correlation Between Circulating Biomarkers of Organs Damage and Intraoperative Hypotension Management
Intraoperative hypotension (defined as mean arterial pressure below 65 mmHg) is associated with increased organs dysfunction and mortality.
- Conditions
- Hypotension, Brain Injuries, Renal Failure, Endothelial Dysfunction
- Trial name
- NCT03527758
- Testing
- Flo TracIQ with HPI software
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Catania
Hypertension, Dyslipidemia
Improved Delivery of Cardiovascular Care Through Outreach Facilitation
The aim of the proposed study is to implement and evaluate Outreach Facilitation as a means to increase the uptake of evidence-based practice for secondary prevention and management of patients with established CVD and…
- Conditions
- Hypertension, Dyslipidemia, Diabetes, Chronic Kidney Disease
- Trial name
- IDOCC (NCT00574808)
- Testing
- Outreach Facilitation implementing elements of the Chronic Care Model
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- C. T. Lamont Primary Care Research Centre
Kidney Failure, Chronic
Creation of Arteriovenous Ante-brachial Fistula Under Axillary Block Versus Local Anesthesia : Impact on Early Complications
Recommended by the KDOQI vascular access guidelines, antebrachial arteriovenous fistula is the best primary vascular access for hemodialysis in patients with end stage renal disease.
- Trial name
- FAV ss ALR (NCT02722096)
- Testing
- Axillary block anesthesia with Ropivacaine and Lidocaine, Local anesthesia with Ropivacaine and Lidocaine
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease and Hypertension
A Phase III Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin on CKD Progression in Participants With CKD and High Blood Pressure.
The purpose of this study is to measure the efficacy and safety of baxdrostat/dapagliflozin in participants ≥ 18 years of age with CKD and HTN.
- Trial name
- NCT06268873
- Testing
- Baxdrostat/dapagliflozin
- Where
- 565 sites in United States, Argentina and 36 more
- Volunteers
- 2,554 people
- Sponsor
- AstraZeneca
End Stage Renal Disease, Thrombosis
Access II - Trial of Warfarin to Prevent Malfunction of Haemodialysis Catheters
This study examines whether low intensity, dose adjusted warfarin prolongs the time to mechanical failure of hemodialysis catheters without resulting in an unacceptable rate of bleeding.
- Conditions
- End Stage Renal Disease, Thrombosis, Bleeding
- Trial name
- NCT00157651
- Testing
- warfarin
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.