Clinical trials: Vascular Thrombosis
Pulmonary Embolism
Macitentan to Prevent PRVO
About half of patients who suffer of a pulmonary embolism (blood clots in the lungs), do not clear completely the clots overtime, increasing the risk of having a new blood clot in the lungs and elevated blood pressure in the…
- Trial name
- MAC-PRO (NCT05946811)
- Testing
- Macitentan 10mg
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Cirrhosis, Esophageal and Gastric Varices
Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis
The APIXABAN-PK trial is a prospective, randomized, single-blind, placebo-controlled study designed to evaluate the efficacy and safety of apixaban in combination with carvedilol versus placebo with carvedilol in preventing…
- Conditions
- Cirrhosis, Esophageal and Gastric Varices, Ascites, Hepatic Encephalopathy
- Trial name
- APIXABAN-PK (NCT07521332)
- Testing
- Apixaban, Carvedilol
- Where
- Pakistan
- Volunteers
- 220 people
- Sponsor
- Asian Institute Of Medical Sciences
Cardiovascular Diseases, Heart Diseases
Raynaud's Treatment Study (RTS)
To determine the relative efficacy of usual medical care and a course of treatment by thermal biofeedback in reducing vasospastic attacks characteristic of Raynaud's syndrome.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Raynaud's Disease, Vascular Diseases
- Trial name
- NCT00000530
- Testing
- nifedipine, biofeedback (psychology), electromyography
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Arterial Thrombosis
Arterial Thrombosis and Inflammatory Bowel Disease: a Series of 6 Cases and Literature Review
Vascular complications in patients with inflammatory bowel disease (IBD), comprising mainly Crohn's disease (CD) and ulcerative colitis (UC), representing 2% extra-intestinal complications.
- Trial name
- TAMICI (NCT02896530)
- Testing
- No intervention. Description study
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Branch Retinal Vein Occlusion
Evaluation of Macugen Treatment of Macular Edema Due to Branch Retinal Vein Occlusion
The purpose of this study is to evaluate the effect of intravitreal injections of Macugen every 6 weeks for the treatment of macular edema secondary to branch retinal vein occlusion (BRVO).
- Trial name
- NCT00406107
- Testing
- pegaptanib sodium (Macugen)
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Palmetto Retina Center, LLC
Central Venous Catheter Thrombosis
Early Detection of PICC-related Deep Vein Thrombosis by US Surveillance: an Effective Approach for Secondary Prevention?
Background: PICC-related thrombosis have shown a slightly different pattern of frequency and risk factors, compared with traditional CVC; because of the increasing diffusion of PICCs, they are becoming a somehow independent…
- Trial name
- NCT01779999
- Testing
- PICC-carrying patients
- Volunteers
- 150 people
- Sponsor
- University of Turin, Italy
Post Thrombotic Syndrome, Venous Thromboses
Exercise Tolerance After Venous Recanalization for Post-thrombotic Syndrome
Post-thrombotic syndrome (PTS) is the most frequently observed chronic complication of deep vein thrombosis (DVT), with an estimated cumulative incidence of 20-50%.
- Conditions
- Post Thrombotic Syndrome, Venous Thromboses, Claudication, Intermittent
- Trial name
- ETERecaVSPT (NCT05794932)
- Testing
- Stress test
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Montpellier
Heart Defects, Congenital
Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt Palliation
This study is the extension of the CLARINET study [NCT00396877 -EFC5314] in neonates or infants with cyanotic congenital heart disease palliated with a systemic-to-pulmonary artery shunt.
- Trial name
- CLARINET LT (NCT00833703)
- Testing
- Clopidogrel
- Where
- 15 sites in United States, Brazil and 13 more
- Volunteers
- 49 people
- Sponsor
- Sanofi
Coronary Artery Disease
The E-SERIES Registry for Supralimus® Coronary Stent for the Treatment of Unselected Patients With Coronary Lesions
E-SERIES Registry evaluate the procedural and clinical outcomes of the Supralimus® SES in the treatment of unselected, high risk patients having coronary Artery blockage in the real world clinical practice.
- Trial name
- NCT01368627
- Testing
- Supralimus® Sirolimus-Eluting Coronary Stent
- Where
- 7 sites in Brazil
- Volunteers
- 1,274 people
- Sponsor
- Sahajanand Medical Technologies Limited
Thromboembolism, Deep Vein Thrombosis
DVT After Cardiac Procedure
Patients undergoing electrophysiology studies (EPS) and cardiac ablation procedure for the treatment of cardiac arrhythmias may be at increased risk of deep vein thrombosis (DVT) during or after the procedure, which may lead to…
- Trial name
- NCT03877770
- Where
- 5 sites in United Kingdom
- Volunteers
- 82 people
- Sponsor
- Manchester University NHS Foundation Trust
Venous Thromboembolism, Cancer
Secondary Prevention of VTE in Patients With Cancer and Catheter-Related Upper Extremity Deep Vein Thrombosis
This trial seeks to evaluate a management strategy after the acute treatment duration (≥ 3 months of therapeutic anticoagulation) for patients with cancer and catheter-related upper extremity deep vein thrombosis (DVT).
- Conditions
- Venous Thromboembolism, Cancer, Upper Extremity Deep Vein Thrombosis, Catheter-Related Infections
- Trial name
- STREAM-Line (NCT06603870)
- Testing
- Anticoagulation Therapy
- Where
- 2 sites in Canada
- Volunteers
- 330 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiometabolic Health
Cardioprotective Properties of ELAIOTSIPOURA
Several studies over the last decades have demonstrated the important role of nutrition for either the prevention of chronic diseases, such as cardiovascular disease and cancer, or the increase of their risk.
- Trial name
- NCT04440202
- Testing
- Conventional sea bream, Enriched sea bream
- Where
- Greece
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Thrombophlebitis
Comparison of Dwell Time of Open Versus Closed Type Peripheral Intravenous Cannula
Studies have shown that stabilisation devices are associated with fewer complications and lower failure rates in peripheral catheters.3,6,7 Although closed-system peripheral catheters offer potential advantages, such as reduced…
- Trial name
- COT-cannula (NCT07182877)
- Testing
- Closed-type peripheral cannula, Open type peripheral cannula
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Venous Thromboembolism
Safety and Efficacy of Therapeutic Anticoagulation With Tinzaparin During Pregnancy Via Weight-based Dosing
The purpose of this study is to evaluate the safety and efficacy of therapeutic anticoagulation with tinzaparin during pregnancy via weight-based dosing.
- Trial name
- NCT00851864
- Testing
- Tinzaparin
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Venous Thromboembolism
Prevention of Venous Thromboembolism in Subjects Undergoing Hip Fracture Surgery or Surgery in the Lower Extremities
The study objective is to evaluate the efficacy and safety of oral YM150 for prevention of venous thromboembolism in subjects undergoing hip fracture surgery or surgery in the lower extremities.
- Trial name
- NCT00937911
- Testing
- YM150
- Where
- 8 sites in Japan
- Volunteers
- 101 people
- Sponsor
- Astellas Pharma Inc
Thromboembolism
Special Drug Use Investigation for ARIXTRA® (Fondaparinux) Injection
This post-marketing surveillance study was designed to collect and assess the information on proper use of fondaparinux injection, such as the safety and efficacy under actual use conditions, in subjects undergoing orthopedic…
- Trial name
- NCT01420809
- Volunteers
- 1,280 people
- Sponsor
- GlaxoSmithKline
Infant Development, Infant,Premature
Pacifier Activated Device and Mother's Voice in Infants at High-risk for Cerebral Palsy
The study seeks to determine the efficacy of non-nutritive suck (NNS) training using a pacifier-activated device (PAM) with mothers' voice to condition suck-strength and rhythmicity, in improving the feeding and developmental…
- Conditions
- Infant Development, Infant,Premature, Hydrocephalus, Neonatal Encephalopathy
- Trial name
- NCT03230032
- Testing
- pacifier-activated device
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Atrial Fibrillation, Deep Vein Thrombosis
Predictors of Anticoagulation Control on Warfarin Therapy
The goal of this research study is to develop better dosing of anticoagulation medication in both Caucasian and African Americans through analysis of various genetic factors.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Heart Valve Replacement
- Trial name
- NCT00905177
- Where
- 2 sites in United States
- Volunteers
- 687 people
- Sponsor
- University of Pennsylvania
STEMI
Predictors of Thrombus Burden in STEMI Patients and Their Impact on Outcome
ST-segment elevation myocardial infarction (STEMI) is the most acute manifestation of coronary artery disease and is associated with great morbidity and mortality.(1).
- Trial name
- NCT06471192
- Testing
- PPCI
- Volunteers
- 200 people
- Sponsor
- Assiut University
Retinal Vein Occlusion
Ultra-wide Fluorescein Angiography in Patients With Central Retinal Vein Occlusion Treated by Afilbercept
In patients with macular edema secondary to CRVO, Aflibercept demonstrated efficacy and safety in 2 parallel trials, interventional phase III studies, COPERNICUS study performed in United States and GALILEO study performed in…
- Trial name
- HERMES (NCT02880644)
- Where
- 9 sites in France
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.