Clinical trials: Venous Thromboembolic Event
Healthcare Quality Indicators, Inappropriate Prescribing
Development and Validation of Automated Indicators on the Appropriateness of Oral Anticoagulant Prescriptions
This research focuses on the development and validation of indicators on the appropriateness of oral anticoagulant prescriptions.
- Conditions
- Healthcare Quality Indicators, Inappropriate Prescribing, Anticoagulant Drugs, Atrial Fibrillation
- Trial name
- PACHA (NCT02898090)
- Where
- 4 sites in France
- Volunteers
- 1,213 people
- Sponsor
- University Hospital, Bordeaux
Venous Thromboembolism
Phase IIa Venous Thromboembolism (VTE) Prevention Study In Total Knee Replacement (TKR)
This study was designed to assess the safety and efficacy of GW813893 in the prophylaxis of VTE following TKR and to provide evidence to enable the selection of the appropriate dose(s) and dose regimen of GW813893 for future…
- Trial name
- NCT00541320
- Testing
- GW813893
- Where
- 8 sites in United States
- Sponsor
- GlaxoSmithKline
Intracerebral Haemorrhage (ICH), Cerebral Infarction
The Erlanger Stroke Registry (ESPro) is the Only Ongoing Prospective Population-based Stroke Registry in Germany, Started in 1994. ESPro Includes All Hospitalized and Non-hospitalized Patients With Stroke in the Community of Erlangen (120.000 Inhabitants), With a Long-life Follow-up.
Stroke is a disease that primarily affects older adults and, with an estimated 64,000 deaths in 2024, is one of the leading causes of death in Germany.
- Conditions
- Intracerebral Haemorrhage (ICH), Cerebral Infarction, Cerebral Infarction Due to Thrombosis of Cerebral Arteries, Cerebral Infarction Due to Embolism of Cerebral Arteries
- Trial name
- ESPro (NCT07771335)
- Where
- 3 sites in Germany
- Volunteers
- 17,000 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Venous Thromboembolism, Pulmonary Embolism
Prediction of the COBRRA VTE Anticoagulant Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, DVT
- Trial name
- NCT05264168
- Testing
- Rivaroxaban, Apixaban
- Where
- United States
- Volunteers
- 41,875 people
- Sponsor
- Brigham and Women's Hospital
Venous Thromboembolism, Spinal Cord Diseases
5E Program for Preventing Venous Thromboembolism in Patients With Spinal Cord Disorders
The goal of this quasi-experimental study is to examine the effects of a venous thromboembolism prevention program, or "5E" program, on the rates of venous thromboembolism in patients with spinal cord disorders.
- Conditions
- Venous Thromboembolism, Spinal Cord Diseases, Spinal Cord Injuries, Nurse's Role
- Trial name
- NCT06302478
- Testing
- 5E program
- Where
- Thailand
- Volunteers
- 42 people
- Sponsor
- Khon Kaen University
Venous Thromboembolism
Predictive Value of Whole Blood Coagulation Parameters for Post-discharge Venous Thromboembolism After Cancer Resection
This study plans to learn more about the role of 2 blood tests in predicting who might develop a blood clot in their arm or leg after major surgery.
- Trial name
- NCT01608919
- Testing
- blood tests
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Colorado, Denver
Obesity, Obesity, Morbid
Comparing Anti-XA Levels in Post-Cesarean Patients Undergoing Enoxaparin Thromboprophylaxis
Pregnant and recently postpartum women are at significantly higher risk of developing a blood clot in their arms or legs known as a deep venous thrombosis (DVT) and/or a blood clot in their lungs known as a pulmonary embolism…
- Conditions
- Obesity, Obesity, Morbid, Pregnancy, Complications; Cesarean Section
- Trial name
- NCT02070237
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- MemorialCare Health System
Arrhythmia, Atrial Fibrillation
Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF)
To determine the benefits and risks of oral anticoagulant therapy in reducing embolic stroke and systemic emboli in patients with atrial fibrillation without rheumatic heart disease.
- Conditions
- Arrhythmia, Atrial Fibrillation, Cardiovascular Diseases, Cerebral Embolism and Thrombosis
- Trial name
- NCT00000517
- Testing
- warfarin
- Sponsor
- Massachusetts General Hospital
Venous Thromboembolism
Multiple-Dose Study Apixaban in Pediatric Subjects With an Indwelling Central Venous Catheter
CV185-079 is a multiple dose Apixaban Pharmacokinetics/Pharmacodynamics (PK/PD) study in pediatric subjects. The objective of this study is primarily to study the PK/PD of Apixaban in pediatric subjects with a central venous…
- Trial name
- NCT01195727
- Testing
- Apixaban
- Where
- 14 sites in United States, Belgium and 3 more
- Volunteers
- 13 people
- Sponsor
- Bristol-Myers Squibb
Pulmonary Embolism, Acute Pulmonary Embolism
CLEANer Aspiration for Pulmonary Embolism
To evaluate the safety and efficacy of the Cleaner™ Pro Thrombectomy System for aspiration thrombectomy in patients with acute pulmonary embolism (PE).
- Conditions
- Pulmonary Embolism, Acute Pulmonary Embolism, Cardiovascular Diseases, Venous Thromboembolism
- Trial name
- CLEAN-PE (NCT06189313)
- Testing
- Cleaner Pro Thrombectomy System
- Where
- 14 sites in United States
- Volunteers
- 125 people
- Sponsor
- Argon Medical Devices
Bladder Cancer
Comparison of Apixaban Versus Enoxaparin
The goal of this randomized trial is to compare bladder cancer patient experiences taking prophylactic anticoagulation at home after surgery to remove their bladder.
- Trial name
- CARE (NCT06243510)
- Testing
- apixaban, enoxaparin
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Venous Thromboembolism
Medication Use Evaluation for Enoxaparin in Hospitalized COVID-19 Patients
Retrospective chart review to be conducted at Methodist Richardson Medical Center (MRMC) in Richardson, TX. All adult patients hospitalized with COVID-19 on enoxaparin for DVT prophylaxis will be included.
- Trial name
- NCT05226793
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Methodist Health System
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Venous Thromboembolism
Pharmacokinetics of Enoxaparin in Intensive Care Patients
To evaluate the pharmacokinetics of the thromboprophylactic agent enoxaparin in critically ill patients by comparing plasma anti-factor Xa activity when enoxaparin is administered either as a continuous intravenous infusion or…
- Trial name
- NCT02095509
- Testing
- Enoxaparin
- Where
- 2 sites in Finland
- Volunteers
- 39 people
- Sponsor
- Tampere University Hospital
Venous Thromboembolism, Hemorrhage
A Clinical Cohort Study of Safety and Effectiveness of Venous Thromboembolism Prophylaxis in Critical Ill Patients
The purpose of this study is to analyze the effect of the prophylaxis of venous thromboembolism in the critical ill patients, and at the same time, to find out the risk of venous thromboembolism and hemorrhage events occurred…
- Trial name
- VTEH (NCT02213978)
- Where
- China
- Volunteers
- 1,114 people
- Sponsor
- Beijing Chao Yang Hospital
Venous Thromboembolism
The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients
Trauma patients are at high risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE). The incidence of DVT varies greatly from 5-63% among studies depending on patient's individual risk factors, modality of…
- Trial name
- NCT00531843
- Testing
- fondaparinux sodium, sequential compression devices
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mary Knudson, M.D.
Sleep Apnea Syndromes, Venous Thromboembolism
Sleep Apnea and Tromboembolic Disease
There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality.
- Trial name
- NCT00501358
- Where
- Spain
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Venous Thromboembolism
Efficacy and Safety of TAK-442 in Subjects Undergoing Total Knee Replacement
The purpose of this study is to determine if TAK-442, once daily (QD) or twice daily (BID), is as safe and effective as enoxaparin in preventing the development of blood clots after knee replacement surgery.
- Trial name
- NCT00641732
- Testing
- TAK-442, Enoxaparin
- Where
- 64 sites in United States, Canada
- Volunteers
- 1,045 people
- Sponsor
- Takeda
Transient Ischemic Attack, Ischemic Stroke
Philippine Neurological Association One Database - Stroke
This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients hospitalized for transient ischemic attack (TIA) or stroke in the 11 accredited adult neurology training…
- Conditions
- Transient Ischemic Attack, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- PNA1DB-Stroke (NCT04972058)
- Where
- 11 sites in Philippines
- Volunteers
- 14,800 people
- Sponsor
- Philippine Neurological Association
Sickle Cell Disease, Central Venous Catheter Thrombosis
THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS)
Research Question: In adult SCD patients with CVC, is it feasible and safe to conduct an adequately powered RCT to evaluate the use of rivaroxaban as thromboprophylaxis in this population? Study Design: The study is a vanguard…
- Conditions
- Sickle Cell Disease, Central Venous Catheter Thrombosis, Venous Thromboembolism
- Trial name
- THIS (NCT05033314)
- Testing
- Rivaroxaban 10 MG
- Where
- 3 sites in Canada
- Volunteers
- 4 people
- Sponsor
- University Health Network, Toronto