Clinical trials: Ventilation
Postoperative Pulmonary Complications, Impaired Oxygenation
PEEP Strategies and Mechanical Power in Robotic Surgery
Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.
- Conditions
- Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation
- Trial name
- NCT07536464
- Testing
- Fixed PEEP Ventilation, Decremental PEEP Strategy, Incremental PEEP Strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Obesity (Disorder), Ventilation Homogeneity
Positional Effects on Lung Ventilation and Perfusion in Obesity
Electrical Impedance Tomography (EIT) is a non-invasive, bedside monitoring tool that provides real-time information on regional ventilation and perfusion.
- Conditions
- Obesity (Disorder), Ventilation Homogeneity, Perfusion, Ventilation Perfusion Mismatch
- Trial name
- NCT07341113
- Testing
- Standardized body positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Koç University
Mechanical Ventilation, Clinical Competence
Using Real-Time Lung Visuals to Reduce Mental Strain and Improve Diagnosis Speed
The goal of this clinical simulation study is to learn if a "Digital Twin" graphical lung display reduce the mental workload of clinicians.
- Conditions
- Mechanical Ventilation, Clinical Competence, Education Curriculum, Self Concept
- Trial name
- VERDICT (NCT07511712)
- Testing
- Real-time Graphical Lung Function Visualization (Digital Twin), Standard Ventilator Waveform Monitoring
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²)
Comparison of Mask Ventilation in Obese Patients by Differents One Hand Techniques
The goal of this controled clinical trial study to know if hook tecnique method is better than other traditional one hand ventilation methods in acheiving effective ventilation in obese patients .
- Conditions
- Mask Ventilation, Obese Patients (BMI ≥ 30 kg/m²), Obesity & Overweight, Bag-mask Ventilation
- Trial name
- E&c / T&E (NCT06817083)
- Testing
- E-C Clamp Technique, T-E Technique, The Hook Technique
- Where
- Egypt
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Aswan University
Positive Pressure Ventilation
Flow- Versus Volume-controlled Ventilation During Robot-assisted Laparoscopic Radical Prostatectomy
During robot-assisted laparoscopic radical prostatectomy (RALRP), patients are placed under general anesthesia and supported with mechanical ventilation.
- Trial name
- NCT07453810
- Testing
- Flow-Controlled Ventilation, Volume-Controlled Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Mechanical Ventilation Complication
Determination of Normal Values of Regional Pulmonary Strain Using a New Ultrasonographic Tool in Healthy Volunteers
Mechanical ventilation is frequently used in the operating room and the intensive care settings. Although essential in many cases, mechanical ventilation can be responsible for ventilator-induced lung injury (VILI).
- Trial name
- Strain (NCT04194346)
- Testing
- Lung ultrasound
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Heart Valvular Disease, Coronary Arteriosclerosis
Comparison of Airway Management With Bronchial Blocker and Double-Lumen Tube in Single-Lung Ventilation
In this study, the primary aim is to compare the impact of using a double-lumen tube and bronchial blocker for single-lung ventilation in patients undergoing minimal invasive cardiac surgeries on postoperative pulmonary…
- Conditions
- Heart Valvular Disease, Coronary Arteriosclerosis, One-lung Ventilation
- Trial name
- NCT06299735
- Testing
- Minimally Invasive Cardiac Surgery (airway management with double-lumen tube), Minimally Invasive Cardiac Surgery (airway management with endobronchial blocker)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Critically Ill, Ventilation Therapy; Complications
Consensus Statements on Airway Clearance Interventions in Intubated Critically Ill Patients--Protocol for a Delphi Study
Intubated critically ill patients are susceptible to secretion accumulation because of compromised airway clearance. Various airway clearance interventions are employed to prevent complication(s) arising from mucus retention.
- Conditions
- Critically Ill, Ventilation Therapy; Complications, Mucus Retention, Airway Clearance Impairment
- Trial name
- ACCorDingly (NCT06649734)
- Testing
- Delphi Study
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
One-Lung Ventilation, Thoracic Surgery
Left Double Lumen Tube Selection
The aim of this study was to determine the accuracy and practicality of ultrasound in the selection of double lumen tube and whether the complications that may occur intraoperatively and postoperatively can be reduced.
- Trial name
- NCT06457763
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Marmara University
Weaning Failure of Mechanical Ventilation
Speckle Tracking Echocardiography for the Prediction of Weaning Failure
Deciding the optimal timing for extubation in patients who are mechanically ventilated can be challenging, and traditional weaning predictor tools are not accurate.
- Trial name
- NCT03657524
- Testing
- echocardiography
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Respiratory Failure, Mechanical Ventilation
A Study of Communication Between Clinicians, Patients, and Families in the Intensive Care Unit (ICU)
The purpose of this study is to investigate a specific approach to patient care called a time-limited trial (TLT). This approach is sometimes used for people who develop critical illness and are cared for in an intensive care…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Life-Supporting Treatments, Communication
- Trial name
- TIME (NCT06042621)
- Where
- 5 sites in United States
- Volunteers
- 7,818 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Difficult Intubation, Difficult Mask Ventilation
Ultrasound Predictors of Difficult Airway in Adults
Difficult airway management is a major cause of perioperative complications. Standard bedside airway assessment tests may have limited ability to predict difficult intubation and difficult mask ventilation.
- Conditions
- Difficult Intubation, Difficult Mask Ventilation, Difficult Airway
- Trial name
- NCT07383610
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Dynamic Balance, Hop Performance and Maximum Voluntary Ventilation (MVV) in Professional Football Players
Core Stability Training With Balloon Breathing on Balance and Performance in Football Players
Football players require good core strength and balance to perform well and reduce the risk of injury. The muscles of the trunk and diaphragm play an important role in maintaining stability, posture, and movement control during…
- Trial name
- NCT07387029
- Testing
- Core Stability Training, Balloon Breathing Exercise
- Where
- United Arab Emirates
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Lung Perfusion, Respiratory Physiology
Effects of Inspiratory vs Expiratory Breath-Hold on Lung Perfusion Measured by EIT Saline Indicator Method: A Self-Controlled Study
This study aims to compare lung perfusion distribution between inspiratory breath-hold and expiratory breath-hold phases using the saline indicator method combined with electrical impedance tomography (EIT).
- Conditions
- Lung Perfusion, Respiratory Physiology, Electrical Impedance Tomography, Ventilation-Perfusion Mismatch
- Trial name
- NCT07303972
- Testing
- Electrical Impedance Tomography Saline Indicator Procedure, Electrical Impedance Tomography Device
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Intraoperative Lung Protective Ventilation
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic.
- Trial name
- IOLPVCZ (NCT07282899)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Thoracic Surgery With One-lung Ventilation, VExUS
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute…
- Conditions
- Thoracic Surgery With One-lung Ventilation, VExUS, Fluid Management, Acute Kidney Injury
- Trial name
- VEXUS (NCT07258875)
- Testing
- Venous Excess Ultrasound, Standard of Care (SOC)
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Crete
Cuff Pressure, Mechanical Ventilation
Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Patients
This prospective, randomized controlled cross-over study compares automatic (IntelliCuff®) and manual methods of endotracheal tube cuff pressure (CP) monitoring in pediatric intensive care patients.
- Conditions
- Cuff Pressure, Mechanical Ventilation, Pediatric Intensive Care
- Trial name
- NCT06965400
- Testing
- Automatic Cuff Pressure Control
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Face Mask Ventilation in Neonatal Resuscitation
Applied Forces During Neonatal Ventilation With Different Face Masks
This trial compares the applied forces exerted on the face of a modified preterm neonatal manikin with three different face masks.
- Trial name
- NCT07161752
- Testing
- Anatomical face mask 1, Anatomical face mask 2, Round face mask
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Acute Respiratory Failure, Mechanical Ventilation
Personalized Decision-Aid to Guide Tracheostomy and Prolonged Mechanical Ventilation Decision-Making
The goal of this study is to determine the Usability and Acceptability of a personalized online decision support tool for patients, families, and providers considering long-term breathing support options for patients who cannot…
- Conditions
- Acute Respiratory Failure, Mechanical Ventilation, Tracheostomy
- Trial name
- NCT07223918
- Testing
- TRACH-Support
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Healthy Adults, Mechanical Ventilation Dependence
Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude
This study investigates whether respiratory muscle training (RMT) and dietary nitrate supplementation can improve exercise tolerance under simulated moderate altitude conditions.
- Conditions
- Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training
- Trial name
- NCT07216755
- Testing
- Respiratory Muscle Training (RMT), Dietary Supplement: Beetroot Juice Concentrate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Embry-Riddle Aeronautical University