Clinical trials: Ventilation
Tricuspid Regurgitation, Mechanical Ventilation Pressure High
Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients
Prospective observational cohort study within the Pediatric Intensive Care Unit (PICU). We will perform point-of-care-ultrasound (POCUS) to quantify tricuspid regurgitant jet velocity (TRJV) on mechanically ventilated (MV)…
- Conditions
- Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
- Trial name
- NCT06229886
- Testing
- Application of positive-end-expiratory pressure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Ventilation, Exercise
Wetsuit and Life Jacket Induced Effects on Spirometry and VO2 in Windsurfers
The purpose of this study is to investigate the effect of wearing both neoprene suit and life jacket on respiratory capacities at rest and cardiopulmonary capacities during exercise in windsurfers.
- Trial name
- WINDSURF (NCT03440294)
- Testing
- resting standard spirometry, maximum exercise testing
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Healthy
The Effects of Different Flow Settings on Lung Impedance
This prospective, randomized crossover trial will enroll adult healthy volunteers. Initially, the subject's peak inspiratory flow will be measured using a mask connected with a respiratory monitor.
- Trial name
- NCT06228703
- Testing
- High-flow nasal cannula device with flow setting at 40 L/min or higher
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Healthy Young Adults
High vs Low Volume Intensity Training With IMT On Pulmonary Function And Breathing Efficiency On Recreational Swimmers.
This study aims to evaluate the impact of inspiratory muscle training (IMT) on respiratory function and swimming performance in competitive swimmers.
- Trial name
- NCT06604741
- Testing
- Assigned Interventions for LVIMT, Assigned interventions for HVIMT
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Breathing Exercises, Telerehabilitation
The Effect of Telerehabilitation-Based Respiratory Exercise Programs on Lung Capacity
It is a prospective randomized controlled trial. In this project, it is aimed to examine the effect of telerehabilitation-based instrumental and noninstrumental respiratory exercise program on lung capacities.
- Trial name
- NCT06303479
- Testing
- Non-Instrumental breathing exercise group, Instrumental breathing exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Respiratory Depression, Cannabis Use
Influence of Δ9-tetrahydrocannabinol (THC) on Oxycodone Induced Ventilatory Depression in Healthy Volunteers
Rationale: Opioid misuse and abuse are common problems in the Western world. The rate of unintentional drug overdose is rapidly increasing, not only in the Unites States but also in the Netherlands.
- Conditions
- Respiratory Depression, Cannabis Use, Opioid Use
- Trial name
- COXY (NCT05235503)
- Testing
- Medicinal cannabis in combination with oxycodon
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Obstructive Sleep Apnea
TipTraQ Home Sleep Test Validation Study, VGH
A validation study has been designed to assess the performance of a home sleep test device, TipTraQ, for screening sleep apnea. The study involves participants wearing the TipTraQ device on their fingertip during a traditional…
- Trial name
- NCT06474390
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- PranaQ Pte. Ltd.
Covid19, Stress
A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls
The study is a randomized controlled trail with an observational arm and aims at collecting information on the prevalence of COVID 19 infection in seasoned yoga practitioners by comparing it with the prevalence of COVID-19…
- Conditions
- Covid19, Stress, Anxiety Depression
- Trial name
- NCT04498442
- Testing
- Simha Kriya, Reading a Book
- Where
- United States
- Volunteers
- 8,519 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Respiratory Insufficiency
Effect of Non-invasive Ventilation (NIV) on Cerebral Oxygenation
SUMMARY AND AIM Background: The proper management of brain oxygenation is an essential component of all anaesthesiologic procedures.
- Trial name
- NCT02454582
- Testing
- Somanetics INVOS Cerebral Oxymeter 5100C
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ass.-Prof. PD Dr. Klaus Ulrich Klein
Hypertrophic Cardiomyopathy
Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)
The investigators are trying to find out how common sleep apnea is in hypertrophic cardiomyopathy. The purpose of this study is to see if sleep apnea is common in hypertrophic cardiomyopathy and if its presence is associated with…
- Trial name
- NCT03327623
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Breath Training Styles
Neurological Evidence of Diverse Self-Help Breathing Trainings with Virtual Reality and Bio-Feedback Assistance
The goal of this research is to learn about the neuro-mechanism beneath breath training, mindfulness meditation, or periods of idleness.
- Trial name
- NCT06656741
- Testing
- Resting State, Mindful Breathing, Guided Breathing
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Hei-Yin Hydra Ng
CHEYNE Stokes Respiration
Baclofen and Hypoxia-induced Periodic Ventilation
Periodic ventilation that includes CHEYNE Stokes ventilation is a pathological pattern characterized by alternating periods of hyperpneas and apnea-hypopneas.
- Trial name
- PERIODIBAC (NCT01095679)
- Testing
- Baclofen
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Newborns
The Effect of Mother's Voice on the Levels of Pain and Comfort in Newborns
This study was conducted in a randomized controlled experimental type to determine the effect of maternal voice during care on pain and comfort level in term newborns receiving mechanical ventilation.
- Trial name
- Newborn (NCT06387888)
- Testing
- Listening to mother's voice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Subclinical Cardiovascular Impairments, Obstructive Sleep Apnea Syndrome
Cardiovascular Impairments and Obstructive Sleep Apnea Syndrome
Which are the anthropometric parameters and/or of severity of the syndrome of apnea of sleep (SAS) which make it possible to anticipate occurred of vascular anomalies, anatomical and/or functional precociously found among…
- Trial name
- INFRASAS (NCT01089257)
- Where
- 3 sites in France
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Nasal Obstruction
Hypnosis to Perform Awake Intubation
Awake intubation is a recommended safety procedure in specific cases where the intubation or ventilation before general anesthesia is at risk.
- Trial name
- Hypnotube (NCT02513511)
- Testing
- laryngoscopy under hypnosis
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Healthy
AZD8848 Single Ascending Dose Study
This study will investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of single ascending doses of AZD8848 in healthy subjects.
- Trial name
- NCT01560234
- Testing
- AZD8848
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Respiration Disorders
Comparative Study Between the AirGoTM System and Standard Tests in the Assessment of the Respiratory Function
The study aims at evaluating the AirGoTM system's performance, as compared to standard pulmonary function tests.
- Trial name
- AirGoTM (NCT03368612)
- Testing
- Electronic evaluation system
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale Santa Croce-Carle Cuneo
Asthma
Combined Effects of Inspiratory Muscles Training With Pilate Training in Asthma Patients
Asthma is a chronic (long-term) condition that affects the airways in the lungs. The airways are tubes that carry air in and out of your lungs. In asthma the airways can become inflamed and narrowed at times.
- Trial name
- NCT06762236
- Testing
- Pillatate Training
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Infant, Newborn, Diseases, Intubation Complication
Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation
The goal of this study is to perform a quality control assessment of our local intubation protocol in any newborn infant requiring endotracheal intubation in the delivery room or neonatal intensive care unit at the Department of…
- Trial name
- IntubAID (NCT06139809)
- Testing
- Intubation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
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