Clinical trials: Ventilation Therapy; Complications
Inhalation Therapy; Complications
The Effect of Stress Ball Utilisation on Treatment Duration, Dyspnea Severity and Anxiety Level in Nebuliser Therapy
Nebul Therapy is very effective in quickly improving the symptoms of respiratory system diseases. While applying this treatment, patients are expected to complete a sufficient period of time.
- Trial name
- NCT06297356
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Prematurity, Respiratory Distress Syndrome
Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants
Approval of surfactant by the FDA in 1989 for the treatment of Respiratory Distress Syndrome (RDS) in premature infants greatly improved survival rates.
- Conditions
- Prematurity, Respiratory Distress Syndrome, Patent Ductus Arteriosus
- Trial name
- CAST (NCT00767039)
- Testing
- Survanta (beractant), Curosurf (poractant)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alan Fujii
Muscle Weakness, Syndrome; Institutionalization
Respiratory Muscle Training in Institutionalized Elderly Population
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the frail elderly.
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Other Diagnoses, Comorbidities, and Complications
- Trial name
- NCT01624272
- Testing
- Threshold® Inspiratory Muscle Trainer (Respironics® Health Scan Inc. Cedar Grove, NJ, USA)., Yoga Pranayama breathing exercises
- Where
- 3 sites in Spain
- Volunteers
- 71 people
- Sponsor
- University of Valencia
Sepsis, Respiratory Failure
The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit
We sought to determine if there is a benefit to using an insulin drip to control hyperglycemia in the surgical critical care unit for patients who undergo general and vascular surgery.
- Conditions
- Sepsis, Respiratory Failure, Renal Failure, Surgical Site Infection
- Trial name
- NCT00282594
- Testing
- Novolin R (human recombinant Insulin)
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Genesys
Ventilation Therapy; Complications, Right Ventricular Function
Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography
Effects of APRV on right ventricular function in patients with acute respiratory distress syndrome by transthoracic echocardiography
- Conditions
- Ventilation Therapy; Complications, Right Ventricular Function, ARDS, Transthoracic Echocardiography
- Trial name
- NCT05414110
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Communication, Ventilation Therapy; Complications
Manually Operated Communication System
The objective of this study is to gather initial information about the testing of a novel manual communication system - which is currently called MOCS, for Manually Operated Communicated System - for mechanically ventilated…
- Trial name
- NCT03630003
- Testing
- MOCS, Post-use interview
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- J. Matthias Walz
Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD
Controlled Versus Standard Oxygen Therapy in ICU Patients With Acute Exacerbation of COPD
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Acute exacerbations frequently require intensive care unit (ICU) admission.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Acute Exacerbation of COPD, Intensive Care Unit (ICU), Controlled Oxygen Therapy
- Trial name
- OXYCOPD-ICU (NCT07842510)
- Testing
- Controlled oxygen therapy, Standard oxygen therapy
- Where
- 2 sites in Tunisia
- Volunteers
- 240 people
- Sponsor
- Hôpital Universitaire Taher Sfar
Lung Neoplasms, Thoracic Surgery Lung
Telerehabilitation Exercise Program for Postoperative Recovery in Lung Cancer.
Lung cancer is one of the leading causes of cancer-related morbidity and mortality worldwide. Thoracic surgery remains the treatment of choice for patients with early-stage disease; however, postoperative recovery is frequently…
- Trial name
- TEPUL (NCT07861282)
- Testing
- Therapeutic Exercise-Based Telerehabilitation, Usual Postoperative Care
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- University of Seville
Lung Injury, Acute, Ultrasound Therapy; Complications
Features of Regional Perfusion of Lung Consolidation
The aim of this study is to evaluate the potential usefulness of lung ultrasound to assess the size and perfusion of consolidation and explore their relationships with clinical outcome.
- Trial name
- NCT05647967
- Testing
- Ultrasound
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Deglutition Disorders, Mechanical Ventilation Complication
PReventing the EffectS of Intubation on DEglutition
An early intervention for swallowing disorders (i.e., dysphagia) during endotracheal intubation may improve patient outcomes. The investigators propose treatment sessions targeting sensorimotor integration, strength, and range of…
- Conditions
- Deglutition Disorders, Mechanical Ventilation Complication, Complication of Ventilation Therapy
- Trial name
- PRESIDE (NCT02442102)
- Testing
- Exercise and sensory stimulation
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Johns Hopkins University
Ventilation Therapy; Complications
Physiological Dead Space Measured by Volumetric Capnography in BiPAP and APRV .
Background and Rationale : Mechanical ventilation is an essential component of the care of patients with respiratory failure.Biphasic positive Airway Pressure (BiPAP) and Airway Pressure release ventilation (APRV) are relatively…
- Trial name
- NCT03218943
- Testing
- APRV ventilation mode, BIPAP ventilation moood
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kasr El Aini Hospital
Ventilation Therapy; Complications, Congenital Heart Disease
Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children
Interventional Trial to determine the Effect of different PEEP levels on Cardiac output and right-ventricular function in mechanically ventilated children < 5 years of age with congenital heart disease.
- Conditions
- Ventilation Therapy; Complications, Congenital Heart Disease, Children, Only, Hemodynamic Instability
- Trial name
- IPCOM (NCT06270485)
- Testing
- PEEP
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 58 people
- Sponsor
- Charite University, Berlin, Germany
Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal)
Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study
The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS).
- Conditions
- Respiratory Distress Syndrome (& [Hyaline Membrane Disease]), Respiratory Distress Syndrome (Neonatal), Respiratory Distress Syndrome (RDS), Respiratory Distress Syndrome of Newborn
- Trial name
- NCT07550218
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Vastra Gotaland Region
Tumor of Lung Parenchyma, Complication of Ventilation Therapy
Effects of Succinylcholine on Nonintubated Thoracoscopic Surgery
A safe and effective surgical environment is important for nonintubated thoracoscopic surgery. The investigators hypothesize that mini-dose succinylcholine can induce ultra-short period of apnea, by which the ventilatory…
- Conditions
- Tumor of Lung Parenchyma, Complication of Ventilation Therapy, Atelectasis
- Trial name
- NCT03469323
- Testing
- Succinylcholine
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression
Effects of Osteopathic Treatment on Pulmonary Function After Coronary Artery Bypass Graft Surgery
The purpose of this study is to determine the short and long term effects of osteopathic treatment on pulmonary function, pain and quality of life in patients after coronary artery bypass graft (CABG) surgery.
- Conditions
- Mechanical Complication of Coronary Artery Bypass Graft, Respiratory Depression, Pain, Quality of Life
- Trial name
- OSTinCARE (NCT01714791)
- Testing
- Usual care, Osteopathic treatment
- Where
- Belgium
- Volunteers
- 112 people
- Sponsor
- Hartcentrum Hasselt
Stillbirth, Infant, Low Birth Weight
UniSA BackOff! Study: Adelaide PrenaBelt Trial
Stillbirth (SB) is a devastating complication of pregnancy and contributes to over 2 million deaths globally every year. Over 20 million infants are born every year with low birth weight (LBW), which is associated with a twenty…
- Conditions
- Stillbirth, Infant, Low Birth Weight, Infant, Very Low Birth Weight, Sleep-Disordered Breathing
- Trial name
- NCT04437407
- Testing
- PB2-1 prototype, PB2-2 prototype, PB2-3 prototype
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shiphrah Biomedical Inc.
Prematurity, Respiratory Distress Syndrome, Newborn
Infantile NO Replenishment as a New Therapeutic Possibility
Case-control study of inhaled Nitric Oxide (iNO) treatment of full-term and preterm infants. The main objective of this study is to investigate the association between premature birth and its later comorbidities (neuroendocrine…
- Trial name
- miniNO (NCT04914806)
- Where
- 3 sites in France, Greece and 1 more
- Volunteers
- 240 people
- Sponsor
- National and Kapodistrian University of Athens
Ventilation Therapy; Complications, Diaphragm Disease
Real-time Effort Driven VENTilator Management
This study is a Phase II controlled clinical trial that will obtain comprehensive, serial assessments of respiratory muscle strength and architecture to understand the evolution of ventilator-induced respiratory muscle weakness…
- Conditions
- Ventilation Therapy; Complications, Diaphragm Disease, Pediatric Respiratory Diseases
- Trial name
- REDvent (NCT03266016)
- Testing
- Computerized Ventilator Protocol, Esophageal Manometry, Respiratory Inductance Plethysmography (RIP)
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- Children's Hospital Los Angeles
Morbid Obesity
Effects of Preoperative Respiratory Physical Therapy on Postoperative Respiratory Function After Bariatric Surgery
Background. Morbidly obese patients show an increased risk of hypoxemia and a higher incidence of postoperative pulmonary complications during the postoperative period resulting in prolonged hospital length of stay when compared…
- Trial name
- NCT01828632
- Testing
- Respiratory Physical Therapy
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Apnea of Prematurity
Clinical Study of Caffeine for Apnea of Prematurity
The aim of the present Phase III study is to evaluate the safety, efficacy and pharmacokinetics of Caffeine Citrate for treatment of apnea of prematurity in Japan.
- Trial name
- NCT01408173
- Testing
- NPC-11 for intravenous or oral administration.
- Where
- 3 sites in Japan
- Volunteers
- 24 people
- Sponsor
- Nobelpharma