Clinical trials: Ventilatory Physiology, active
Study the Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
Effectiveness of Combined Manual Therapy and Pulmonary Exercises on Ventilatory Function in Patients with Restrictive Lung Diseases
This research investigates the effect of selective manual therapy techniques on chest expansion, pulmonary function (FVC, FEV1, and FEV1/FVC ratio), and functional capacity, in restrictive lung disease patients.
- Trial name
- NCT06681701
- Testing
- Combined Manual Therapy and Pulmonary Exercises
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- South Valley University
COPD (Chronic Obstructive Pulmonary Disease)
Digital High-Intensity Respiratory Muscle Training on COPD Patients
The goal of this Randomize control trail is to determine the effect of Digital High-Intensity Respiratory Muscle Training on ventilatory Function and Functional Capacity in Patients with COPD It will also learn about the safety…
- Trial name
- COPD (NCT07346261)
- Testing
- Digital Sonmol Respiratory Muscle Trainer, conventional respiratory rehabilitation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Anesthesia, Mechanical Ventilation
The Impact of Lumboscopy Versus Laparoscopy on Ventilatory Mechanics
There are several techniques for performing minimally invasive urological surgeries. Among them, laparoscopic surgery, robotic surgery, and lumboscopy are noteworthy (1).
- Conditions
- Anesthesia, Mechanical Ventilation, Respiratory Physiology
- Trial name
- NCT06776068
- Where
- 2 sites in Chile
- Volunteers
- 40 people
- Sponsor
- University of Chile
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
Rheumatic Arthritis, Lung Function
Manual Diaphragmatic Release on Ventilatory Functions in Women With Rheumatoid Arthritis
Evaluate the effect of manual diaphragmatic release on ventilatory functions in women with rheumatoid arthritis
- Trial name
- NCT06716008
- Testing
- Aerobic training, Manual Diaphragm Release
- Volunteers
- 60 people
- Sponsor
- Middle East University
Obesity (BMI>30)
Machine Learning Prediction of Respiratory Muscle Changes and Ventilatory Responses After Incretin-Based Therapy in Obesity
This study aims to evaluate changes in respiratory function, respiratory muscle performance, and ventilatory responses following incretin-based therapy in individuals with obesity, and to identify predictors of these changes…
- Trial name
- NCT07663591
- Testing
- Incretin-based therapy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Body Composition, Cardiovascular Health
Differences in Ventilatory Function, Body Composition, and Cardiorrespiratory Fitness According to Training Status
The goal of this cross-over study is to evaluate the physiological response to exercise and body composition according to training status in participants with a wide spectrum of fitness states.
- Conditions
- Body Composition, Cardiovascular Health, Ventilatory Physiology
- Trial name
- NCT06246760
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Ventilatory Defect, Occupational Lung Diseases
Effect of Aerobic and Resistance Exercise on Quarry Workers
The goal of this randomized clinical trial is to compare the effects of aerobic exercise training and resistance exercise training on ventilatory function in quarry workers.
- Conditions
- Ventilatory Defect, Occupational Lung Diseases, Respiratory Disorders
- Trial name
- AE RE VF (NCT07744334)
- Testing
- Aerobic exercise training, Resistance exercise training
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Cystic Fibrosis (CF), Mucoviscidosis
Prevalence of Exercise-induced Ventilatory Limitation and Associated Factors in Patients With Cystic Fibrosis Receiving Elexacaftor-Tezacaftor-Ivacaftor
Cystic fibrosis is a genetic disorder affecting the entire body and associated with respiratory exacerbations, impaired quality of life and reduced life expectancy.
- Trial name
- MUCOLIMEX (NCT07314229)
- Testing
- Measurement of resistance through forced oscillations and continuous measurement of ventilation and inspiratory capacity during TM6
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Lille
Chronic Obstructive Lung Disease
EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD
This Single-blind, randomized controlled trial will evaluate the effects of 12 weeks of combined VR-guided diaphragmatic breathing (Flowborne) and VR-aerobic cycling (Kinneta) compared with conventional pulmonary rehabilitation…
- Trial name
- VR-COPD (NCT07885995)
- Testing
- VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group
- Volunteers
- 60 people
- Sponsor
- Cairo University
Copd
Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessness
Multicentre, prospective, non-randomised, single-arm, open label, mechanistic study to investigate the mechanism of action of BGF 160 on ventilation pattern complexity and variability
- Trial name
- VARI-OSCIL (NCT06110403)
- Testing
- TRIXEO AEROSPHERE
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Lille
Cardiorespiratory Fitness, Metabolic Health
Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults
The purpose of this single-group diagnostic validation and test-retest reliability study is to determine whether a novel Incremental Step Test (IST) can accurately assess cardiorespiratory fitness and ventilatory thresholds in…
- Conditions
- Cardiorespiratory Fitness, Metabolic Health, Cardiac Function, Pulmonary Function
- Trial name
- VALID-IST (NCT07829003)
- Testing
- Cardiopulmonary Exercise Test, Incremental Step Test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Sleep-disordered Breathing, Chronic Opioid Use
Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.
This study will evaluate whether supplemental oxygen given during sleep improves breathing stability and sleep-disordered breathing in adults who use prescription opioids long term.
- Trial name
- OPIO2 (NCT07923760)
- Testing
- Supplemental Oxygen
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, San Diego
Pulmonary Edema Cardiac Cause
HF vs NIV in Acute Cardiogenic Pulmonary Edema
The study's primary aim is to compare the effects of two different ventilation modalities, non-invasive positive-pressure ventilation (NPPV) and high-flow nasal cannulae (HFNC), in the acute cardiogenic pulmonary edema (ACPE)…
- Trial name
- HFvsNIV (NCT05989139)
- Testing
- NPPV/HFNC, HFNC/NPPV
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tetralogy of Fallot (TOF), Adults With Repaired Tetralogy of Fallot
Effect of Exercises on Ventilatory Function in Adult With TOF
The goal of this clinical trial is to learn if combined inspiratory muscle training and aerobic exercise can improve ventilatory function in adults with repaired Tetralogy of Fallot (TOF).
- Trial name
- NCT07326228
- Testing
- aerobic exercise, respiratory muscle training
- Volunteers
- 60 people
- Sponsor
- Cairo University
Cardiovascular Physiology
Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
This study will evaluate the effects of four weeks of oral supplementation with a double-standardized tart cherry (Prunus cerasus) and aronia (Aronia melanocarpa) extract on cardiovascular regulation and exercise performance in…
- Trial name
- NCT07885098
- Testing
- Standardized Tart Cherry and Aronia Extract
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Central Obesity, Ventilatory Function
Effect of Thoracic Mobilization in People With Central Obesity
The goal of this clinical trial is to learn whether Mulligan thoracic mobilization in extension improves ventilatory functions and chest wall expansion in adults with central obesity.
- Trial name
- NCT07718178
- Testing
- Mulligan Thoracic Mobilization, low carbohydrate, Aerobic Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University