Clinical trials: Ventral Hernia Repair
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Ventral Hernia
Risk Factors and Results of Emergency Ventral Hernia Repair
The aim of present study was to evaluate the clinical course after emergency ventral hernia repair in terms of 30-day-readmission, -reoperation and -mortality and to identify risk factors for emergency repair.
- Trial name
- NCT01589276
- Where
- Denmark
- Volunteers
- 10,976 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Incisional Ventral Hernia
Cytokine Response to Abdominal Wall Reconstruction
This is a prospective, observational translational study of patients undergoing major abdominal wall reconstruction with primary fascial closure.
- Trial name
- NCT07422584
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Ventral Incisional Hernia
Open Complex Ventral Incisional Hernia Repair Using Biosynthetic Material for Midline Fascial Closure Reinforcement
Prospective, multicenter, observational study to evaluate performance of GORE® BIO-A® Tissue Reinforcement when used to reinforce midline fascial closure in single-staged open complex ventral incisional hernia repair.
- Trial name
- COBRA (NCT01325792)
- Testing
- GORE® BIO-A® Tissue Reinforcement
- Where
- 9 sites in United States, Netherlands
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Ventral Hernia, Umbilical Hernia
Does a Transabdominal Plane Block Decrease Patient Pain After Ventral Hernia Repair?
The purpose of this study is to determine if a Transabdominal Plane Block will decrease patient pain and pain medication use after a laparoscopic ventral (ventral, umbilical, incisional) hernia repair with mesh.
- Conditions
- Ventral Hernia, Umbilical Hernia, Incisional Hernia, Postoperative Complications
- Trial name
- NCT02007096
- Testing
- Transabdominal Plane Block, Non Transabdominal Plane Block
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ventral Incisional Hernia
Tension in Posterior Component Separation for Abdominal Wall Reconstruction
The purpose of this study is to measure the changes in tension after each release in a standard posterior component separation during abdominal wall reconstruction.
- Trial name
- NCT05142761
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Michael Rosen
Ventral Hernia, Umbilical Hernia
Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
Ventral hernias can be repaired using a variety of techniques, with smaller defects often being amenable to minimally invasive surgical (MIS) approaches.
- Conditions
- Ventral Hernia, Umbilical Hernia, Epigastric Hernia
- Trial name
- NCT04150796
- Testing
- Ventral Hernia Repair
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ventral Hernia
Prospective Study of Ventral Hernia Repair
Immediate post-operative abdominal compartment syndrome is a feared complication after hernia repair in patients with a "loss of abdominal domain." Replacement of the viscera within an unyielding stiff abdominal wall may…
- Trial name
- NCT00894582
- Testing
- Components separation hernia repair
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Ventral Hernia
Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
The aim of this study was to perform a randomised clinical trial comparing the use of closed-suction tubular drains and progressive tension sutures in individuals with large incisional hernias subjected to onlay mesh repair to…
- Trial name
- NCT02163460
- Testing
- Drain, Progressive Tension Sutures
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Oeste do Paraná
Umbilical Hernia, Epigastric Hernia
Risk Factors for Poor Outcome After Epigastric and Umbilical Hernia Repair
Umbilical and epigastric hernia repairs are common and performed by numerous surgical techniques. Considering that the hernia repairs in general are relatively small and simple procedures there are disproportionate poor results.
- Trial name
- NCT01665859
- Where
- Denmark
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Hernia
Negative Pressure Incisional Wound Therapy for High-risk Ventral Hernia Repair
The investigators are testing the ability of vacuum dressings to improve wound healing for patients having large hernias surgically repaired who are at risk of having wound complications.
- Trial name
- N-PITH (NCT04455724)
- Testing
- Negative pressure incisional wound therapy, Standard sterile dressing
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- McMaster University
Hernia, Ventral, Neuromuscular Blockade
Prospective Randomized Trial of Moderate vs Deep Neuromuscular Blockade During Laparoscopic Ventral Hernia Repair
The proposed study aims to assess the effect of different levels of muscle relaxation on the success of low-pressure insufflation, surgical conditions and patient recovery following laparoscopic repair of a ventral hernia (VHR)…
- Conditions
- Hernia, Ventral, Neuromuscular Blockade, Pneumoperitoneum
- Trial name
- NCT03201744
- Testing
- Patients will be randomized to moderate (TOF 1-2) or deep (post tetanic count 1-2) relaxation. Low pressure insufflation (start pressure set at 8 mm Hg)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stony Brook University
Ventral Hernia
Video-based Collaborative Learning to Improve Ventral Hernia Repair
Recent studies demonstrate the critical role of individual surgeon performance, including both the approach they take to an operation as well as their technical skill, in determining patient outcomes.
- Trial name
- NCT04173884
- Testing
- Coaching, Constructive Feedback
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hernia, Ventral, Hernia Incisional
Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh
This study compares short term outcomes of patients undergoing a hernia repair with heavy weight mesh vs medium weight mesh in clean-contaminated and contaminated cases.
- Trial name
- NCT06409091
- Testing
- Medium weight or Heavy weight mesh
- Where
- United States
- Volunteers
- 1,496 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Ventral Hernia
Reoperation Rate Versus Clinical Recurrence After Ventral Hernia Repair
The risk for recurrence after ventral hernia repair is often based on reoperation rates with short follow-up rather than recurrences identified by clinical examinations.
- Trial name
- NCT01325246
- Where
- Denmark
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Pain, Quality of Life
Robotic Versus Hybrid Assisted Ventral Hernia Repair
Laparoscopic ventral hernia repair (LVHR) may be associated with chronic pain, seroma formation, bulging and failure to restore abdominal wall function.
- Conditions
- Pain, Quality of Life, Recurrence
- Trial name
- ROHYB (NCT05233020)
- Testing
- robotic, hybrid
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Analgesia
Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial
We plan to demonstrate the superiority of epidural anaesthesia/analgesia in repairs of large ventral hernias as compared with a conventional narcotic analgesia regimen. We hypothesize that: 1.
- Trial name
- NCT00529074
- Testing
- Epidural Catheter for Analgesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Ventral Hernia
Comparative Study of Biologic Mesh Versus Repair With Component Separation.
The purpose of this study is to compare open abdominal incisional hernia repair using XenMATRIX biologic mesh versus repair with their own tissue.
- Trial name
- Davol (NCT01295125)
- Testing
- XenMATRIX mesh, Open abdominal ventral hernia repair
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Surgical Site Infection
Environmental Risk Factors of Mesh Infection After Abdominal Wall Hernia Repair
Mesh infection is the main complication in abdominal hernia repair. In case of infection, a conservative management of mesh is not always possible.
- Trial name
- NCT04174976
- Testing
- wall hernia repair
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Umbilical Hernia
Self-Expanding Multi-Layered Partially Resorbable Lightweight Polypropylene Mesh Device (Proceed Ventral Patch® Or Pvp®) For The Treatment of Small and Medium Umbilical Ventral Hernias
Meshes-devices using dual-sided mesh technology have been developed for the specific indication of small ventral hernias. The design of these meshes allows introduction of a mesh of appropriate size to cover the hernia defect…
- Trial name
- NCT01307696
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Algemeen Ziekenhuis Maria Middelares