Clinical trials: Vertebra; Anomaly
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Vertebral Cervical Fusion Syndrome, Degenerative Disc Disease
Study Using the CervicalStim Device Following Cervical Fusion
This study examines the effect of adjunctive use of the CervicalStim bone growth stimulator on cervical fusion rate in high risk subjects who have undergone cervical fusion surgery.
- Trial name
- NCT03177473
- Testing
- CervicalStim bone growth stimulator
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- Orthofix Inc.
Patients With Kimmerle's Anomaly
Radial Visualization of the Foramen Arcuale Atlantis
Hemodynamics in the craniovertebral zone is often disturbed under the influence of a spondylogenic factor A complication of such changes can be from a slight decrease in cerebral circulation to ischemic changes in the vascular…
- Trial name
- NCT05160259
- Testing
- Radial visualization of the foramen arcuale atlantis
- Where
- Uzbekistan
- Volunteers
- 60 people
- Sponsor
- Samarkand State Medical Institute
Epileptic Seizure, Intracranial Tumor
Our Anesthesia Experience During MRI Scan
In this study we aim to investigate the relationship between our anesthesia practice and post procedure complications after MRI scanning with sedation. This is a retrospective, single center observational study.
- Conditions
- Epileptic Seizure, Intracranial Tumor, Intracranial Hypertension, Intracranial Aneurysm
- Trial name
- NCT03123302
- Where
- Turkey (Türkiye)
- Volunteers
- 977 people
- Sponsor
- Akdeniz University
Congenital Spinal Deformity, Congenital Kyphoscoliosis
Vertebral Column Resection (VCR) in Congenital Kyphoscoliosis (CKS)
Congenital spinal deformities (CSD) are caused by early embryologic errors in vertebral column formation. Spinal cord malformations are present in approximately one third of patients, even associated cardiac, renal, and…
- Trial name
- NCT03524027
- Testing
- Posterior Vertebral Column Resection (PVCR)
- Volunteers
- 20 people
- Sponsor
- Assiut University
Neuromuscular Scoliosis, Spine Deformity
Mini-invasive Spine Surgery for Neuromuscolar Scoliosis
Neuromuscular scoliosis (SNM) are deformities related to the impairment of normal function of the central nervous system (CNS) and/or peripheral nervous system (PNS) resulting in alterations to the of the functional unit…
- Conditions
- Neuromuscular Scoliosis, Spine Deformity, Surgery, Vertebral Fusion
- Trial name
- MISNM (NCT06367933)
- Testing
- mini-invasive spine surgery
- Where
- Italy
- Volunteers
- 1 people
- Sponsor
- Istituto Ortopedico Rizzoli
Lumbar or Thoraco-lumbar Adult Deformity
Sagittal Plane Correction With Pass-LP Device in Adult Deformity Patients
The purpose of this study is to evaluate the correlation between the restoration of the sagittal balance and the improvement of the Quality of Life for patients with adult scoliosis, treated with a polyaxial system (PASS® LP…
- Trial name
- NCT01635322
- Testing
- Polyaxial posterior spinal fusion system
- Where
- 2 sites in United States, France
- Volunteers
- 54 people
- Sponsor
- Medicrea International
Vertebral Osteomyelitis
Comparison of Two Antimicrobial Therapy Duration for Spondylodiscitis
Duration of antimicrobial therapy for spondylodiscitis is not standardized; it could vary from 6 weeks to several months depending on the medical habits.
- Trial name
- DTS (NCT00764114)
- Testing
- antibiotic
- Where
- France
- Volunteers
- 351 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sickle Cell Disease, Sickle Cell Anemia
Sickle Cell Disease (SCD) Bone Pain Study
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis
- Trial name
- NCT05283148
- Testing
- Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Davis
Scoliosis Idiopathic Adolescent
Effect of a 16-Week Physiotherapeutic Corrective Exercise Program on Spinal Deformities in Adolescent Idiopathic Scoliosis
Brief Summary Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity that may progress during adolescence and lead to postural asymmetry, spinal rotation, pelvic imbalance, reduced spinal mobility, and…
- Trial name
- SPINE-AIS16 (NCT07736456)
- Testing
- Structured Physiotherapeutic Corrective Exercise Program, Standard Physiotherapy Exercise Program
- Where
- Kosovo
- Volunteers
- 68 people
- Sponsor
- Alma Mater Europaea - Slovenia
Craniofacial Microsomia, Hemifacial Microsomia
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies.
- Conditions
- Craniofacial Microsomia, Hemifacial Microsomia, Oculo-Auriculo-Vertebral-Syndrome, Goldenhar Syndrome
- Trial name
- CLOCK (NCT02224677)
- Where
- 5 sites in United States
- Volunteers
- 417 people
- Sponsor
- Seattle Children's Hospital
Chronic Venous Insufficiency, Peripheral Arterial Disease
Outpatient Office Based Endovascular Procedures
The results of this study will serve as a starting point for future trials concentrating on the effectiveness and clinical outcomes of the procedures performed in an office based angiosuite.
- Conditions
- Chronic Venous Insufficiency, Peripheral Arterial Disease, Dialysis Access Malfunction, Arterio-venous Fistula
- Trial name
- NCT04054440
- Where
- United States
- Volunteers
- 26,000 people
- Sponsor
- Methodist Health System
Thoracolumbar Spinal Fusion
Retrospective Evaluation of Upper Instrumented Vertebrae (UIV) Screw Loosening Following Spine Surgery
The REESE study is looking at information from past spine surgeries to learn how often screws placed at the top of a spinal fusion become loose over time.
- Trial name
- REESE (NCT07838571)
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Hemivertebra
Assessment and Follow-up of Surgical Treatment of Hemivertebra in Children
The treatment of child's vertebral malformations has evolved a lot including the realization of surgical vertebral resections. The surgical techniques used are multiple, require heavy surgery, one or more approaches and surgical…
- Trial name
- NCT03772119
- Testing
- Surgical resection
- Where
- 13 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Tours
Radius; Deformity, Hip Osteoarthritis
Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology
Digital surgery, in combination with patient specific instrumentation (PSI) is being used more and more in traumatology due to its proven benefits and applications.
- Conditions
- Radius; Deformity, Hip Osteoarthritis, Hip Arthritis, Hip Arthropathy
- Trial name
- NCT06603831
- Testing
- patients treated using 3D technology and Patient-Specific Instrumentation, Patients treated with conventional surgery, without using 3D technology
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Corporacion Parc Tauli
Disc Degenerative Disease, Spondylolisthesis
A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
The primary objective of this study is to demonstrate that the efficacy and safety of Spine fusion system manufactured in China is no inferior than imported product.
- Conditions
- Disc Degenerative Disease, Spondylolisthesis, Spinal Fracture, Spinal Deformity
- Trial name
- NCT02252185
- Testing
- Johnson&Johnson Medical Suzhou made Spine Fusion System, Imported EXPEDIUM screws and OPAL cage
- Where
- 8 sites in China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Vertebral Body Compression
Efficacy of Kyphoplasty With a New Intervertebral Expander
Balloon kyphoplasty is a well-established treatment option to achieve pain relief and to correct kyphotic deformity caused by osteoporotic vertebral compression fracture.
- Trial name
- NCT03521661
- Testing
- Kyphoplasty
- Volunteers
- 41 people
- Sponsor
- Mohammad ARAB MOTLAGH
Vertebra; Degeneration, Spinal Trauma
SpineTRACK Registry - Spinal Outcomes Registry
The Spine TRACK Spinal Surgery Registry is a prospective multi-center observational data collection initiative, to capture clinical and radiographic outcomes in candidates for spine surgery with degenerative, deformity, and…
- Conditions
- Vertebra; Degeneration, Spinal Trauma, Spinal Deformity
- Trial name
- NCT01372592
- Testing
- Surgery
- Where
- 28 sites in United States, Brazil
- Volunteers
- 8,079 people
- Sponsor
- NuVasive
Achondroplasia
Radiological Analysis on Patients With Achondroplasia Disorder
Achondroplasia is a genetic disorder characterized by disproportionate short stature. It affects about 1 in 2500 live births in the world.
- Trial name
- Achondroplasia (NCT04184817)
- Testing
- Collection of clinical data registered in Easily software
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Low Back Pain, Muscle Strength
Back Squat Exercise Treatment for Low Back Pain: Clinical Trial
Summary: Low back pain is the leading cause of deficiency and loss of productivity worldwide. No evidence of any particular exercise was more effective than another for treating nonspecific low back pain.
- Conditions
- Low Back Pain, Muscle Strength, Visceral Obesity, Spine Disease
- Trial name
- NCT04691258
- Testing
- Experimental: Complete Group, Active Comparator: Restricted Group
- Where
- 3 sites in Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Goias