Clinical trials: Vertical Bone Defects
Infra-bony Periodontal Defect
Effect of Gingival Mesenchymal Stem Cell-Derived Small Extracellular Vesicles in Management of Infra-bony Periodontal Defect
The goal of the study to evaluate whether the adjunctive use of gingival mesenchymal stem cell-derived extracellular vesicles (GMSC-derived EVs) combined with β-tricalcium phosphate (β-TCP) and a collagen membrane results in…
- Trial name
- NCT07867067
- Testing
- Gingival mesenchymal stem cell derived small extracellular vesicles, β-calcium triphosphate (β-TCP) + collagen membrane
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Ain Shams University
Vertical Alveolar Bone Loss
Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix…
- Trial name
- NCT06639555
- Testing
- PRP( platelet rich plasma), EMD (Enamel Matrix Derivative), Guided Tissue Regeneration (barrier membrane)
- Where
- Bulgaria
- Volunteers
- 48 people
- Sponsor
- Tsvetalina Gerova-Vatsova
The Presence of Horizontal and Vertical Alveolar Defects in Both Jaws, Inadequate for the Placement of at Least Two Fixtures, Even ≤6 mm Long Ones
Guided Bone Regeneration With Custom Made Meshes
Twenty patients underwent a guided bone regenerative procedure with the application of a virtually projected customized mesh as containment and stabilizer of particulate bone graft.
- Trial name
- NCT04942223
- Testing
- guided bone regeneration
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Periodontitis, Tooth Migration
Timing of Orthodontic Therapy and Regenerative Periodontal Surgery in Advanced Periodontitis Patients With Pathologic Tooth Migration
Pathologic tooth migration (PTM) is a common complication of advanced periodontitis and often motivation for patients to seek orthodontic therapy.
- Conditions
- Periodontitis, Tooth Migration, Intrabony Periodontal Defect
- Trial name
- NCT02761668
- Testing
- ParS+Ortho 4W, ParS+Ortho 6M
- Where
- 2 sites in Germany, Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Vertical Bone Defects, Missing Tooth/Teeth
Effect of Changing Grafting Sequences During Sinus Lifting & Simultaneous Implant Placement in the Gained Bone Using Customized Surgical Guide
The aim of this randomized clinical trial is to evaluate the effect of changing the sequence of bone grafting during maxillary sinus lifting and simultaneous dental implant placement.
- Trial name
- NCT07816107
- Testing
- Traditional sequence, Modified sequence
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Cairo University
Intra-bony Pockets
The Use of Injectable Plasma Versus the Use of Simvastatin Gel in Surgical Management of Bony Defect in Dentistry
Simvastatin (SMV) is one of the family members of statins, it has been showed in many previous studies that the simvastatin when dissolved with methylcellulose in situ gel with a concentration of 1.2% (SMV) approximately, can…
- Trial name
- NCT04824898
- Testing
- Simvastatin, injectable plasma rich fibrin
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Ain Shams University
Periodontal Diseases
Regenafil Versus Demineralized Freeze Dried Bone Allograft (DFDBA) for Periodontal Defects
The purpose of this research study was to determine whether treatment with the bone grafting material Regenafil was as effective as the standard treatment using demineralized freeze dried bone allograft (DFDBA).
- Trial name
- NCT00255970
- Testing
- DFDBA, Regenafil
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- RTI Surgical
Periodontal Bone Loss, Periodontitis
The Role of Granulation Tissue in Periodontal Regeneration
The goal of this observational study is to distinguish the infectious, healing, and regeneration-related characteristics of two types of gingival granulation tissues, namely infra-osseous and supra-osseous granulation tissues, in…
- Conditions
- Periodontal Bone Loss, Periodontitis, Periodontal Disease, Periodontal Diseases
- Trial name
- NCT07254117
- Where
- Latvia
- Volunteers
- 46 people
- Sponsor
- Riga Stradins University
Recession
Modified Connective Tissue Graft Wall With Wing Technique for Posterior Teeth
The investigators reported here the application of usage modified connective tissue graft wall technique for posterior teeth. The treatment outcomes suggested the efficacy of the used technique in treating recession defects…
- Trial name
- NCT03716752
- Testing
- Modified connective tissue graft wall with wing technique
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University