Clinical trials: Vestibular Loss, Bilateral
Vestibular Disorder, Bilateral Vestibulopathy
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
This study has three main goals (1) to explore the effects of electrical stimulations of the peripheral vestibular system(2) to assess the potential of this technique to rehabilitate basic vestibular functions in patients with…
- Conditions
- Vestibular Disorder, Bilateral Vestibulopathy, Bilateral Vestibular Loss
- Trial name
- NCT05246553
- Testing
- Electrical stimulation of the vestibular system, Electrical stimulation of the auditory system, Bilateral vestibulopathy Patients (BV)
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nils Guinand
Neuropathy, Cerebellar Ataxia
Evaluation of the Peripheral Nerve Ultrasound as a Diagnostic Tool in CANVAS Neuropathies
Cerebellar ataxia with neuropathy and bilateral areflexia syndrome (CANVAS) is a late onset neurodegenerative disorder with a slowly progressive ataxia.
- Conditions
- Neuropathy, Cerebellar Ataxia, Neurodegenerative Diseases
- Trial name
- CANVAS (NCT05095870)
- Testing
- No intervention
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Reflex, Abnormal, Bilateral Vestibulopathy
Covert Saccade Triggers in Bilateral Vestibular Hypofunction
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Conditions
- Reflex, Abnormal, Bilateral Vestibulopathy, Healthy Volunteers
- Trial name
- CS-TRIGGER (NCT04268615)
- Testing
- Covert Saccades and Virtual Reality, Actives versus passives Head Impulses, Visually guided saccades
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Bilateral Vestibular Loss, Vestibular Rehabilitation
Vestibular Rehabilitaion in Bilateral Vestibular Hypofunction
The purpose of this study is to determine the etiological factors that constitute bilateral vestibular hypofunction and to investigate the effect of vestibular rehabilitation in these patients.
- Trial name
- NCT05676307
- Testing
- Vestibular Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Istanbul Gedik University
Bilateral Vestibular Loss
VertiGO! - Get up and GO! With the Vestibular Implant
In the VertiGO! trial 13 participants with bilateral vestibulopathy (BV) and severe sensory neural hearing loss in the ear to be implanted will receive a combined cochlear (CI) and vestibular implant (VI), capable of stimulating…
- Trial name
- NCT04918745
- Testing
- Cochlear Vestibular Implant (CVI) - in-hosptial, Cochlear Vestibular Implant (CVI) - home-use (preference)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Maastricht University Medical Center
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss
The goal of the study was to evaluate the safety, tolerability, and the potential ability of CGF166 delivered through IL-infusion to improve hearing.
- Trial name
- NCT02132130
- Testing
- CGF166
- Where
- 4 sites in United States
- Volunteers
- 22 people
- Sponsor
- Novartis Pharmaceuticals
Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency
Long Term Outcomes After Vestibular Implantation
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency, Bilateral Vestibulopathy, Gentamicin Ototoxicity
- Trial name
- NCT06500975
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD)
Vestibular Implantation in Older Adults
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases
- Trial name
- NCT05676944
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Cochlear Trauma, Vestibular Disorder
Vestibular Function in Cochlear Implants
The objective of this study is to identify possible preoperative risk factors including genetic background and to suggest the optimal test battery of vestibular function in cochlear implant recipients
- Conditions
- Cochlear Trauma, Vestibular Disorder, Deafness, Bilateral
- Trial name
- NCT05795530
- Testing
- cochlear implantation
- Where
- Czechia
- Volunteers
- 57 people
- Sponsor
- Charles University, Czech Republic
Sensorineural Hearing Loss, Bilateral Hearing Loss
Comparative Analysis of Hearing Outcomes: Robotic vs. Manual Insertion of Cochlear Implants
This research study is evaluating two different methods of cochlear implant (CI) insertion - robotic-assisted insertion and manual insertion - to better understand how they affect hearing outcomes.
- Conditions
- Sensorineural Hearing Loss, Bilateral Hearing Loss, Cochlear Implantation, Hearing Disorders
- Trial name
- NCT07081542
- Testing
- IotaSoft Robotic Insertion System, Manual Cochlear Implant Insertion
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- AdventHealth
Cerebellar Ataxia
Evaluation of the Diagnostic Value of Video-oculography in CANVAS Neuronopathies
Cerebellar ataxia syndrome with neuropathy and vestibular areflexia (CANVAS) is a genetic pathology of recent discovery (bi-allelic expansion in intron 1 of the RFC1 gene with AAGG repetition).
- Trial name
- VOG-Neuropat (NCT05278091)
- Testing
- None, pure observationnal study
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy
MRI Performance and Risk Factors in Bilateral Vestibular Hypofunction
Bilateral vestibular hypofunction (BVH) is a chronic disorder in which the balance organs or vestibular pathways on both sides do not work normally.
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibulopathy, Presbyvestibulopathy
- Trial name
- MPARFIBVH (NCT07709143)
- Testing
- Multimodal Neuroimaging and Vestibular Function Assessment
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai 6th People's Hospital
Vestibular Disorder
Hearing Loss, Vestibular Loss and Cognitive Performance
Hearing loss is an established independent risk factor for dementia. Likewise, recent research demonstrated cognitive deficits in subjects with vestibular loss.
- Trial name
- NCT03690817
- Testing
- RBANS-H, virtual Morris Water Maze
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Idiopathic Bilateral Vestibulopathy
Idiopathic Bilateral Vestibulopathy: Peripheral Vestibular Disorders and Their Repercussions
The goal of this exploratory study is to gain a better understanding of the symptomatology of idiopathic bilateral vestibulopathy (IBV) by characterising as precisely as possible the type and intensity of each patient's…
- Trial name
- VBI (NCT06476587)
- Testing
- Assessment of postural stability and active motion perception, Cognitive tests, Eccentric axis rotation
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Vestibular Diseases
Covert-saccades, Dynamic Visual Acuity and Quality of Life
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Trial name
- COSQOL (NCT02753179)
- Testing
- Head Impulse Tests, Dynamic visual acuity Test (DVAT), VEMPs & VEMPo
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Characterisation of Low Frequency Hearing and Vestibular Function in Patients Undergoing Cochlear Implantation
The study will follow a cohort of CI-candidates becoming CI-user, till two years postoperative. A through-out assessment of both their audiological and vestibular status will be carried out at multiple fixed timepoints over 2…
- Trial name
- NCT06021132
- Testing
- cochlear implant
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Aalborg University Hospital
Cerebellar Ataxia, Neuropathy
Evaluation of Urinary Dysfunction in CANVAS Patients
The investigator wishes to evaluate the prevalence of urinary symptoms in patients diagnosed with Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS).
- Conditions
- Cerebellar Ataxia, Neuropathy, Vestibular Areflexia
- Trial name
- UROCANVAS (NCT06817707)
- Testing
- Evaluation of urinary dysfunction in patients with CANVAS
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD)
Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Other Disorders of Vestibular Function, Bilateral, Bilateral Vestibular Deficiency (BVD), Gentamicin Ototoxicity, Labyrinth Diseases
- Trial name
- NCT05674786
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Vestibular Dysfunction, Bilateral Vestibular Loss
Spatial Orientation, Navigation, and Neuropsychologic Function in Patients With Vestibular Implant
The vestibular system, located in the inner ear, provides information to the brain information about how head acceleration and orientation relative to gravity.
- Conditions
- Vestibular Dysfunction, Bilateral Vestibular Loss, Vestibular Implant
- Trial name
- NCT07627087
- Testing
- vestibular implant stimulation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency
Inventory of Radiological and Vestibular Function in Cochlear Implant Candidates
In 2014 radiological lesions at one or more semicircular canals (SCC) were described using CT \& MR imaging in subjects presenting advanced hearing and vestibular deterioration caused by the p.P51S mutation in COCH.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibular Deficiency, DFNA9, Radiology
- Trial name
- NCT04066270
- Testing
- video nystagmography
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Jessa Hospital