Clinical trials: Veterans Health
Stress Disorders, Post-Traumatic
Telephone Case Monitoring (TCM) for Veterans With Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to test whether providing PTSD patients additional support by telephone (in addition to usual outpatient care) after they discharge from residential treatment improves those patients' outcomes and…
- Trial name
- TCM-PTSD (NCT00288860)
- Testing
- Telephone monitoring, Treatment-As-Usual
- Where
- 5 sites in United States
- Volunteers
- 837 people
- Sponsor
- VA Office of Research and Development
PTSD, Depression
Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care
OEF/OIF/OND war Veterans have unique post-deployment care needs that the VA is striving to understand and address. Unfortunately, there is a significant disparity in utilization of mental health (MH) care and VA access as most…
- Conditions
- PTSD, Depression, Substance Use Disorder, Traumatic Brain Injury
- Trial name
- eSDM (NCT03539068)
- Testing
- WEB-ED+ Treatment Arm
- Where
- United States
- Volunteers
- 1,312 people
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Enhancing Delivery of Problem Solving Therapy Using SmartPhone Technology
This project will be the first to evaluate the Moving Forward app in VA. Identifying an effective treatment for anxiety and depression in primary care is imperative within Veterans Health Administration as they are both common…
- Trial name
- NCT01891734
- Testing
- Problem Solving Therapy plus Moving Forward, Problem Solving Therapy
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiovascular Disease, Hypertension
Unmet Social Needs Study
The impacts of unmet social needs, such as homelessness, inconsistent access to food, and exposure to violence on health are well-established, especially for cardiovascular disease.
- Conditions
- Cardiovascular Disease, Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- NCT04977583
- Testing
- Unmet Need Screening, Unmet Need Referral - Resource Sheet, Unmet Need Referral Assistance
- Where
- 3 sites in United States
- Volunteers
- 479 people
- Sponsor
- VA Office of Research and Development
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Depression, Elderly
Telepsychology-Service Delivery for Depressed Elderly Veterans
The purpose of this study is to see whether therapy for elderly adults with major depression can be delivered effectively using videoconferencing technology ("telepsychology"), which allows a therapist and patient who are not in…
- Trial name
- NCT00324701
- Testing
- Telepsychology, Face-to-face therapy
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- US Department of Veterans Affairs
Mental Health, Depression
Designing a Mobile App to Support Academic Success for Student Veterans
Compared to civilian students in higher education, student Veterans have high rates of mental health disorders (e.g., Depression: 24% vs 12.1%).
- Conditions
- Mental Health, Depression, Post-Traumatic Stress Disorder, Anxiety
- Trial name
- NCT05344092
- Testing
- VetEd Mobile Application
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging, Mobility Limitations
Life 2: Improving Fitness and Function in Elders
The purpose of this study is to determine whether a 12-month physical activity counseling program, compared to usual care, improves physical performance in a sample of older veterans.
- Trial name
- Project LIFE (NCT00435188)
- Testing
- Multi-component physical activity counseling program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Healthcare Disparities, Mental Health
Improving Patient-Provider Communication to Reduce Mental Health Disparities
The purpose of this study was to develop and pilot test an intervention to reduce mental health disparities for racially and ethnically minoritized Veterans receiving outpatient VA mental health services.
- Trial name
- PARTNER-MH (NCT04515771)
- Testing
- PARTNER-MH
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Schizophrenia, Chronic Illness
Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)
This project evaluates the implementation and effectiveness of a care model to improve treatment for schizophrenia within the context of diverse VA practices and priorities.
- Conditions
- Schizophrenia, Chronic Illness, Weight Gain, Psychotic Disorder
- Trial name
- EQUIP-2 (NCT00137280)
- Testing
- Collaborative Chronic Illness Care Model
- Where
- 8 sites in United States
- Volunteers
- 1,067 people
- Sponsor
- VA Office of Research and Development
Concussion, mTBI
Neurofeedback Impact on Veterans With mTBI
This study will evaluate neurofeedback (NFB) training as a low risk, non-invasive, effective treatment for Veterans diagnosed with mild traumatic brain injury (mTBI) and experiencing chronic post-concussive symptoms (PCSs).
- Conditions
- Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache
- Trial name
- NFBVETmTBI (NCT04195685)
- Testing
- Neurofeedback (NFB)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Diabetes
Caring Others Increasing EngageMent in PACT
This trial will compare two methods of increasing engagement in care and success in diabetes management, among patients with diabetes with high-risk features, who also have family members involved in their care.
- Trial name
- CO-IMPACT (NCT02328326)
- Testing
- CO-IMPACT, PACT
- Where
- 2 sites in United States
- Volunteers
- 478 people
- Sponsor
- VA Office of Research and Development
Tobacco, Posttraumatic Stress Disorder
Improving Functional Outcomes of Veterans With PTSD and Tobacco Dependence
Veterans with PTSD have high rates of smoking (34%-86% vs. 18% in the general population) and have substantial difficulties with quitting tobacco.
- Trial name
- ACT-PT (NCT02576899)
- Testing
- Acceptance and Commitment Therapy for PTSD and Tobacco Use, Freedom From Smoking
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Mental Health, Stress Disorders, Post-Traumatic
Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder
The primary study objective is to conduct a prospective, randomized controlled clinical trial that compares the effectiveness of two approaches for delivering smoking cessation treatment for veterans with posttraumatic stress…
- Conditions
- Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
- Trial name
- NCT00118534
- Testing
- Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
- Where
- 11 sites in United States
- Volunteers
- 943 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Stress Disorders, Post-Traumatic, Depression
Development of a Patient Centered Mental Health Intervention for Recent Veterans
Recent Veterans of the OIF/OEF/OND conflicts are presenting in VA care with high rates of: PTSD, depression, anxiety, and alcohol abuse, reporting significant difficulties with community reintegration, and dropping out of mental…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Anxiety, Substance-Related Disorders
- Trial name
- PCC MH (NCT02943408)
- Testing
- person-centered mental health intervention, health and wellness
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Obesity
Coaching Veterans to Healthy Weights and Wellness
ASPIRE has completed enrollment of patients at the Ann Arbor and Cleveland Medical Centers in a study that is examining the impact of an innovative approach to weight loss ("Aspiring to Lifelong Health in VA", aka "ASPIRE-VA").
- Trial name
- ASPIRE (NCT00967668)
- Testing
- Small change approach to improve physical activity and diet, MOVE! Usual Care
- Where
- 2 sites in United States
- Volunteers
- 481 people
- Sponsor
- US Department of Veterans Affairs
Sleep Initiation and Maintenance Disorders, Post-Traumatic Stress Disorders
Telemedicine Management of Chronic Insomnia
Insomnia is commonly present in Veterans with post-traumatic stress disorder (PTSD). Treatment of insomnia with a specialized type of psychotherapy has been shown to be more effective than treatment with medications.
- Trial name
- VIP (NCT01686438)
- Testing
- Cognitive behavioral therapy for insomnia
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- VA Office of Research and Development
Pain, Migraine
Vagus Nerve Stimulation: Treatment for Gulf Veterans With Gulf War Illness
The researchers propose studying Gulf veterans with Gulf War Illness (GWI), characterized by a problem with widespread pain. Besides their pain, the researchers will also assess the effect of vagus nerve stimulation (VNS) in…
- Trial name
- NCT02791893
- Testing
- VNS device, Inactive device
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Benjamin Natelson
Chronic Pain
Reaching Rural Veterans: Applying Mind-Body Skills for Pain Using a Whole Health Telehealth Intervention - UG3 Pilot Study
This project addresses the significant challenge of providing evidence-based non-pharmacologic pain management to rural-dwelling Veterans in the VA healthcare system who have chronic pain.
- Trial name
- RAMP-Pilot (NCT06568250)
- Testing
- RAMP program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Stress Disorders, Posttraumatic, Depression
Re-Engineering Systems for the Primary Care Treatment for PTSD
The study is an evaluation of a systemic intervention to enhance the delivery of care according to practice guidelines for posttraumatic stress disorder (PTSD).
- Trial name
- RESPECT-PTSD (NCT00373698)
- Testing
- Three Component Model of Collaborative Care
- Where
- 4 sites in United States
- Volunteers
- 195 people
- Sponsor
- US Department of Veterans Affairs