Clinical trials: Vibration; Disorder
Pulmonary Hypertension
Cardiac Magnetic Resonance Imaging and Pulmonary Perfusion
Pulmonary hypertension is a rare severe disease leading to cardiac insufficiency. Treatment depends on the severity of the disease.
- Trial name
- NCT01100008
- Testing
- Magnetic resonance imaging (MRI)
- Where
- France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Toulouse
Colorectal Cancer, Colon Cancer Liver Metastasis
Diffusion-Weighted MRI for Liver Metastasis
The DREAM study will assess the diagnostic accuracy of diffusion-weighted MRI in combination with other imaging modalities (multiparametric MRI and CT Scan) in determining the true status of disappearing liver metastasis (DLM)…
- Conditions
- Colorectal Cancer, Colon Cancer Liver Metastasis, Malignant Neoplasm of Rectum Metastatic to Liver
- Trial name
- DREAM (NCT02781935)
- Testing
- DW-MRI
- Where
- 21 sites in United States, Austria and 3 more
- Volunteers
- 233 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Carpal Tunnel Syndrome
Cerebral Changes Following CTS Treated With Guided Plasticity
70 patients with mild to moderate Carpal tunnel Syndrome (CTS) including 24 patients with unilateral CTS were randomized to treatment with ipsilateral cutaneous forearm deafferentation with an anesthetic cream (EMLA®) or placebo…
- Trial name
- NCT06016049
- Testing
- EMLA® adjuvant, Sensory training
- Volunteers
- 70 people
- Sponsor
- Region Skane
Cardiomyopathy, Hypertrophic
A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
The purpose of this study is to evaluate the mavacamten impact on myocardial structure with cardiac magnetic resonance imaging (CMR) in adult participants with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) [New York…
- Trial name
- MEMENTO (NCT06112743)
- Testing
- Mavacamten
- Where
- 23 sites in United States, Argentina and 4 more
- Volunteers
- 63 people
- Sponsor
- Bristol-Myers Squibb
Heart Failure
A Comparison of Magnetic Resonance Imaging in Persons With Heart Failure to Health, Aged Matched Controls
The purpose of this study is to examine the relation between the structural brain changes associated with heart failure, neurocognitive performance, and how these changes impact self-care behaviors.
- Trial name
- MIND-HF (NCT02572648)
- Testing
- Brain Imaging (Neuroimaging), Cognitive Function Assessment
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emory University
Patellofemoral Pain Syndrome
Impact Of Whole Body Vibration on Planter /Dorsi Flexor Ratio, Pain and Functional Activities in Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) can significantly affect an individual's ability perform to functional activities, such as walking, running, climbing stairs, and sitting for prolonged periods.
- Trial name
- NCT06017778
- Testing
- whole body vibration, traditional exercise group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Heart Failure With Reduced Ejection Fraction (HFrEF), Chronic Heart Failure
Vericiguat and Reverse Remodeling Indices in Heart Failure
The goal of this clinical trial is to investigate how vericiguat benefits adults with stable heart failure with reduced ejection fraction (HFrEF) who are already receiving guideline-directed medical therapy.
- Trial name
- VERI-PATH (NCT07405944)
- Testing
- Vericiguat, Guideline Directed Medical Therapy for Heart Failure (GDMT)
- Where
- 4 sites in Slovenia
- Volunteers
- 70 people
- Sponsor
- University Medical Centre Ljubljana
Crohn Disease
Contrast Ultrasound of the Small Intestine in Patients With Crohns Disease
The purpose of this study is to determine how relevant dynamic ultrasound scans using contrast agents (SonoVue) is in the diagnosis of Crohns disease in the small bowel, compared to dynamic Magnetic Resonance Imaging (MRI) of the…
- Trial name
- KULT (NCT01365767)
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Rune Wilkens
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myocardial Diseases
Improved Detection of Myocardial Fibrosis: a Cardiovascular Magnetic Resonance Imaging Study
Myocardial fibrosis, or scarring, is a common endpoint in many cardiomyopathies and is associated with adverse outcomes, and precise tools to measure myocardial fibrosis are needed.
- Trial name
- NCT06697509
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Akershus
Nicotine Dependence
State and Trait Mediated Response to TMS in Substance Use Disorder
OBJECTIVES: The current protocol seeks to develop brain-based intermediate phenotypes of response to transcranial magnetic stimulation (TMS) in chronic substance use disorder (SUD).
- Trial name
- NCT03707600
- Testing
- TMS
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Patello Femoral Syndrome
Whole Body Vibration and Exercise in Knee Pain
The present study will consist of evaluating the effect of applying an exercise protocol on a vibratory platform in order to provoke immediate influences in the affected systems and in the quality of life of the patients with…
- Trial name
- NCT04031248
- Testing
- Whole body vibration, EXERCISE group
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Miguel Hernandez de Elche
HIV Associated Neurocognitive Disorder
Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
The purpose of this study is to see if paroxetine and fluconazole are safe and effective as a treatment for problems with memory, concentration, thinking, and judgment in people who are infected with HIV.
- Trial name
- ParaFlu (NCT01354314)
- Testing
- Fluconazole, Paroxetine, Paroxetine and Fluconazole
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins University
Wheelchair Users, Athletic Performance
Vibration Therapy in Wheelchair Basketball Players
No study was found that investigated the effect of vibration therapy (VT) on recovery from exercise in WCB players. Therefore, the aim of the study was to investigate the effects of wearable local vibration device on muscle…
- Conditions
- Wheelchair Users, Athletic Performance, Disability, Disabled Persons
- Trial name
- NCT06403384
- Testing
- Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people
- Sponsor
- Karabuk University
Heart Failure
Validation of a Non-invasive Assessment of Central Venous Oxygen Saturation by Using MRI
BOLD measured with MRI may be a useful noninvasive method for the assessment of right ventricular O2 saturation. A validation of this method against right heart catheterization has not been fully performed.
- Trial name
- NCT05161884
- Where
- Germany
- Volunteers
- 135 people
- Sponsor
- German Heart Institute
Adenomyosis
Adenomyosis and Ulipristal Acetate
Evaluation of efficiency of selective progesterone receptor modulators (SPRM) (Ulipristal acetate) on bleeding control and pain for patients with adenomyosis and wish to keep fertility.
- Trial name
- FRA-IIT-UPA (NCT02587000)
- Testing
- Ulipristal acetate
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Memory Disorders, Alzheimer's Disease
Amyloid Plaque and Tangle Imaging in Aging and Dementia
Amyloid senile plaques (SPs) and neurofibrillary tangles (NFTs) are neuropathological hallmarks of Alzheimer's disease (AD) that also accumulate in key brain regions in association with normal aging.
- Trial name
- NCT00355498
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cardiovascular Diseases
Global CMR Registry
The Global CMR Registry aims to promote collaboration of CMR sites worldwide in setting imaging and reporting standards, assessing its diagnostic impact on patient care, and determining the cost-effectiveness of CMR imaging.
- Trial name
- GCMR (NCT02806193)
- Testing
- Cardiovascular Magnetic Resonance Imaging
- Volunteers
- 80,000 people
- Sponsor
- Society for Cardiovascular Magnetic Resonance
Breast Cancer
Efficacy and Safety of Gadobutrol 1.0 Molar (Gadovist) for Breast Magnetic Resonance Imaging (MRI)
The purpose of this study is to look at the efficacy (how does it work) and safety of gadobutrol when used for obtaining MR images of both breasts.Women with a recent diagnosis of breast cancer by mammogram (X-ray examination of…
- Trial name
- GEMMA 2 (NCT01104584)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 48 sites in United States, Argentina and 7 more
- Volunteers
- 460 people
- Sponsor
- Bayer
Distal Radius Fracture, Fall Patients
Vibration Therapy as a Rehabilitation Intervention for Postural Training and Fall Prevention
The occurrence of distal radius fractures is well known to be a sentinel event as these fractures are associated with 2 to 4 times increased risk of subsequent hip fractures in elderly patients.
- Trial name
- NCT03380884
- Testing
- Low-magnitude high-frequency vibration (LMHFV)
- Where
- Hong Kong
- Volunteers
- 232 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong