Clinical trials: Viral Respiratory Tract Infections
COVID19
Expanded Access to Convalescent Plasma for the Treatment of Patients With COVID-19
This expanded access program will provide access to investigational convalescent plasma for patients in acute care facilities infected with SARS-CoV-2 who have severe or life-threatening COVID-19, or who are judged by a…
- Trial name
- NCT04338360
- Testing
- COVID-19 convalescent plasma
- Where
- 12 sites in United States
- Sponsor
- Mayo Clinic
Covid19, Diarrhea
COVID-19 Disease Duration and GIT Manifestations. A New Disease Severity Classification. An Egyptian Experience
The present study conducted to correlate symptoms not only constitutional and respiratory, but GIT as a principle presentation, with laboratory markers and COVID-19 severe acute respiratory syndrome (SARS-COV2) disease outcomes…
- Trial name
- NCT04554979
- Testing
- Hydroxychloroquine Pill
- Where
- Egypt
- Volunteers
- 199 people
- Sponsor
- Cairo University
Acute Viral Pharyngitis
Ectoin® Lozenges in the Treatment of Acute Viral Pharyngitis
This a comparative, open label, parallel group, non interventional study which compares the tolerability and influence of Ectoin containing Lozenges to saline solution and lozenges containing hyaluronic acid for the treatment of…
- Trial name
- NCT02669446
- Testing
- Medical devices, traditional household remedy
- Where
- 4 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Bitop AG
COVID-19
Effects of a N95 Respirator vs Cloth Mask on Exercise Capacity During Treadmill Exercise.
This study intends to find out how a cloth mask may impact exercise capacity, to provide guidance for exercisers to adjust their expectations and training accordingly.
- Trial name
- NCT04415879
- Testing
- N-95 Respirator, Cloth Face Mask
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Corona Virus Infection
The Impact of Camostat Mesilate on COVID-19 Infection
SARS-CoV-2, one of a family of human coronaviruses, was initially identified in December 2019 in Wuhan city. This new coronavirus causes a disease presentation which has now been named COVID-19.
- Trial name
- CamoCO-19 (NCT04321096)
- Testing
- Camostat Mesilate
- Where
- 11 sites in Denmark, Sweden
- Volunteers
- 206 people
- Sponsor
- University of Aarhus
Virus-HIV, Covid19
Impact of the Epidemic of COVID-19 Infection Among People Living With HIV (SARS-CoV-2)
The non-essential and non-urgent follow-up consultations of patients living with HIV were postponed or transformed into "teleconsultation" or exchanges of e-mails between practitioners and patients during COVID-19 epidemic.
- Trial name
- coVIHd-19 (NCT04581746)
- Testing
- questionnaire
- Where
- 3 sites in France
- Volunteers
- 1,800 people
- Sponsor
- Tourcoing Hospital
COVID-19
Add-on Study on WHO Solidarity Trial Plus for COVID-19 in Nepal
Proposal for Sub-Study to be conducted with the WHO Solidarity Plus Trial: Apart from the data been collected as per the WHO Solidarity Trial Plus protocol, Nepal Health Research Council will conduct a sub-study to evaluate some…
- Trial name
- NCT05273242
- Testing
- Artesunate Injection
- Where
- 5 sites in Nepal
- Volunteers
- 400 people
- Sponsor
- Nepal Health Research Council
COVID-19
Open-label, Non-randomized, Non-comparative, Phase II Study of Safety and Immunogenicity of Combination of AZD1222 and rAd26-S for COVID-19 Prevention
The purpose of the study is to assess safety and immunogenicity of heterologous booster vaccine containing combination of AZD1222 and rAd26-S (one of components of Gam-COVID-Vac vaccine) in adult subjects aged ≥ 18 years old to…
- Trial name
- NCT04686773
- Testing
- AZD1222, rAd26-S
- Where
- Azerbaijan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- R-Pharm
COVID-19
Clinical Evaluation of Rapid RNA Test for Covid-19
A new Rapid RNA test for Covid-19 has been developed by Professor Cui and his team at the Department of Engineering Science at the University of Oxford.
- Trial name
- CERrnaTc-19 (NCT05308550)
- Testing
- rapid RT-LAMP test to detect SARS-COV-2 RNA
- Where
- United Kingdom
- Volunteers
- 369 people
- Sponsor
- University of Southampton
HIV Infections, Hypertension
ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE
The goal of this study is to determine the effect of the ENHANCE intervention in improving clinical outcomes and evaluating the effects of the intervention on implementation processes and outcomes.
- Conditions
- HIV Infections, Hypertension, Diabetes Mellitus, Asthma
- Trial name
- ENHANCE (NCT06248190)
- Testing
- ENHANCE intervention (health systems)
- Where
- 32 sites in South Africa
- Volunteers
- 1,837 people
- Sponsor
- University of KwaZulu
COVID-19, Infant, Newborn, Diseases
Long-term Respiratory Complications in Infants With Perinatal COVID-19
Study outcomes and endpoints: Primary outcome: to assess clinical characteristics of infants with confirmed COVID-19 infection at birth and to evaluate long-term respiratory consequences of neonatal COVID-19 infection.
- Conditions
- COVID-19, Infant, Newborn, Diseases, Respiratory Function Tests
- Trial name
- COLF (NCT05793723)
- Testing
- Pulmonary function testing device
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Covid19, SARS-CoV2 Infection
Monitoring the Effectiveness and Safety of COVID-19 Vaccines at National University of Colombia
There are relevant questions that need to be answered about the effectiveness and safety of COVID-19 vaccines. The objective of this observational study is to follow up the clinical outcomes after vaccination in all the…
- Trial name
- NCT04887246
- Testing
- COVID-19 vaccines
- Where
- Colombia
- Volunteers
- 4,078 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Covid19, Femur Fracture
Femoral frACturEs and COVID-19.
Retrospective cohort study comparing the early prognosis after surgically-treated proximal femur fragility fractures in patients affected and not affected by COVID-19.
- Conditions
- Covid19, Femur Fracture, Fragility Fracture
- Trial name
- FACE COVID-19 (NCT04657510)
- Testing
- COVID-19
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
SARS-CoV-2, Seasonal Influenza
A Study of Modified mRNA Vaccines in Healthy Adults
The main goal of this study is to evaluate the safety, reactogenicity, and immunogenicity of study vaccines.
- Conditions
- SARS-CoV-2, Seasonal Influenza, Respiratory Syncytial Virus, Cytomegalovirus
- Trial name
- NCT05397223
- Testing
- mRNA-1273, mRNA-1010, mRNA-1345
- Where
- 8 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Long COVID-19
Effects of Exercise Training on Patients With Long COVID-19
Effects of Exercise training on Patients With Long COVID-19, is a single-center, randomized, controlled trial designed to evaluate the effects of 4- week aerobic exercise administered to patients with long COVID-19 symptoms.
- Trial name
- NCT05961462
- Testing
- Exercise training
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Guangdong Provincial People's Hospital
COVID-19
COVID-19 Screening Program
In view of the recent COVID surge and difficulties in obtaining testing, we aim to increase Point of Care (POC) testing, whereby University of Pennsylvania (Penn) faculty, staff, and trainees who are working in person at Perelman…
- Trial name
- COVID SAFE 2 (NCT05216627)
- Testing
- Self-administered saliva-based viral testing
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Quality of Life, Injection Site Reaction
Simultaneous mRNA COVID-19 and IIV4 Vaccination Study
This study is a prospective, randomized clinical trial. During this study, participants will be randomly assigned to receive quadrivalent inactivated influenza vaccine (IIV4) and mRNA COVID-19 vaccine either simultaneously or…
- Conditions
- Quality of Life, Injection Site Reaction, Adverse Drug Event, Systemic Reaction
- Trial name
- NCT05028361
- Testing
- mRNA COVID-19, IIV4
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Duke University
Covid19
COVID-19 Vaccine Effectiveness in Albanian Health Workers
The purpose of this study is to evaluate the effectiveness of the COVID-19 vaccine in hospital based HWs in Albania. This will answer critical questions about the real-world performance of COVID-19 vaccines in one of the key…
- Trial name
- COVEAL (NCT04811391)
- Testing
- COVID-19 vaccine
- Where
- 3 sites in Albania
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Institute of Public Health, Albania
COVID 19
Comparison of Cardiopulmonary Fitness Level With Normal Values After COVID-19
COVID-19 (Coronavirus disease 2019) is a new infectious disease caused by a virus named as SARS-CoV2 (Severe Acute Respiratory Syndrome Coronavirus-2).
- Trial name
- NCT04753346
- Testing
- Physical Activity Level, Anxiety and Depression Assessment, Exercise Capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Ankara University
Covid19, Nursing Home
Correlation Between the Incidence of COVID-19 in Nursing-homes and the Profile of Nursing Homes in the French Alps
Since the beginning of the COVID-19 outbreak in France, nursing homes (NH) have been heavily affected. In this study, the investigators want to evaluate the factors associated with the occurrence of COVID-19 epidemic clusters…
- Trial name
- PROCOPAD (NCT04695457)
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier Annecy Genevois
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