Clinical trials: Vision
Amblyopia, Myopia
Performance of a Photoscreener for Vision Screening in a Haitian Pediatric Population
Screening of haitian children between the ages of 3 and 6 years old for amblyogenic risk factors with the use of the Spot photoscreener. The photoscreener results will be compared to the complete ophthalmologic evaluation.
- Conditions
- Amblyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- POPH (NCT02655432)
- Testing
- Spot photoscreener, Ophthalmologic evaluation, Cyclopleged refraction
- Where
- 3 sites in Haiti
- Volunteers
- healthy volunteers welcome
- Sponsor
- Université de Montréal
Retinitis Pigmentosa, Glaucoma
Evaluation of Objective Perimetry Using Pupillometer
Objective perimetry can better monitor visual field defects in RP and Glaucoma patients than conventional subjective perimetry.The PLR ( Pupil Light Reflex ) of the short and long wave ratio should be significantly higher in…
- Conditions
- Retinitis Pigmentosa, Glaucoma, Visual Field
- Trial name
- NCT01021982
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Keratoconus, Irregular Astigmatism
Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism
Aberrations are the spreading of light from a point focus. Aberrations of the eyes can be objectively evaluated with a wavefront aberrometer.
- Conditions
- Keratoconus, Irregular Astigmatism, Corneal Ectasia, Aberration, Corneal Wavefront
- Trial name
- WFG Sclerals (NCT04698590)
- Testing
- Wavefront Guided Scleral Lenses, Traditional Scleral Lenses
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cornea and Laser Eye Institute
Glaucoma, Mild Cognitive Impairment
Assessing Neurovisual Function in Patients With Cognitive Impairment
The aim of this study is to measure fitness to drive in patients with a visual and a cognitive impairment. To do so, Ocusweep is used in patients with glaucoma and Mild Cognitive Impairment.
- Conditions
- Glaucoma, Mild Cognitive Impairment, Glaucoma and Mild Cognitive Impairment, Healthy
- Trial name
- NCT03333096
- Testing
- Ocusweep test battery, Neuropsychological test battery
- Where
- Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Glaucoma,Primary Open-Angle ,Primary Angle Closure
Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma
This work aims to study the peripapillary and macular microvascular changes in primary open angle and primary angle closure glaucoma using Optical Coherence Tomography Angiography (OCTA).
- Trial name
- NCT06000176
- Testing
- Optical coherence tomography angiography
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Omar Said
Uveitic Glaucoma, Anterior Uveitis
Aqueous Humor Dynamics and Hypertensive Uveitis
Uveitis is a disease that affects over 2 million people around the globe, and can ultimately lead to blindness. The proportion of patients with uveitis who become blind has not been reduced over the past 30 years, and this is…
- Trial name
- NCT02765308
- Where
- United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Vestibulo-Ocular Reflex, Esports Participation
Comparison of Vestibulo-Ocular Reflex and Cognitive Functions in E-Athletes and Non-Athletes
This study aims to compare cognitive functions and functional vestibulo-ocular reflex (VOR) between e-athletes and non-athletes.
- Conditions
- Vestibulo-Ocular Reflex, Esports Participation, Cognitive Functioning
- Trial name
- NCT07211191
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Concussion, Mild
Novel Protection Against Potential Brain, Hearing and Vision Injury During Blast Wave Exposure
The purpose of the study is to monitor changes in brain structure and function between the pre-training and post-training, in a population of tactical team members wearing the Device and compared to a similar population not…
- Trial name
- BLAST (NCT03017924)
- Testing
- Q collar
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Ophthalmic Solutions, Glaucoma
Evaluation of a New Method for Instilling Eye Drops
The purpose of this project is to demonstrate that there is a new easier method to instill eye drops in ones own eye that is as effective as applying a drop directly to their open eye.
- Trial name
- NCT02697318
- Testing
- Timolol maleate 0.5% ophthalmic solution
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Hyperopia
Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRK
To determine the ability of two topical Nonsteroidal Anti-inflammatory drops (Acular LS \& Nevanac) to help control pain following Photorefractive Keratectomy (PRK).
- Trial name
- NCT00347204
- Testing
- ketorolac (Acular LS), Nepafenac (Nevanac)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center For Excellence In Eye Care
Macular Degeneration
Vision Improvement for Patients With Age-Related Macular Degeneration
This study is being conducted to assess the safety and efficacy of the VIS, LLC (VIS) Opti-K Low Vision Aid Device and treatment to provide vision improvement to patients with age-related macular degeneration.
- Trial name
- NCT06198452
- Testing
- Vision Improvement
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VIS, Inc.
Primary Open-angle Glaucoma
GORE Glaucoma Drainage Implant Clinical Study Dominican Republic
The objective of this early feasibility clinical study is to evaluate the safety and effectiveness of several different GORE Glaucoma Drainage Implant configurations in subjects with primary open-angle glaucoma that is…
- Trial name
- NCT05557058
- Testing
- Gore Glaucoma Device Implant (GORE GDI)
- Where
- Dominican Republic
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- W.L.Gore & Associates
Progressive Supranuclear Palsy, Multiple System Atrophy
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
At present, the diagnosis of Parkinsons disease(PD) mainly relies on clinical symptoms and is easily confused with atypical Parkinsonian syndrome(APS) in the early stages. There is an urgent need for reliable biomarkers.
- Conditions
- Progressive Supranuclear Palsy, Multiple System Atrophy, Parkinson's Disease
- Trial name
- NCT06490926
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Glaucoma
SENSIMED Triggerfish in Closed Eyes
This study investigates the effect of eye opening/closure on the quality of IOP (intraocular pressure) related patterns recorded with SENSIMED Triggerfish.
- Trial name
- NCT01938287
- Testing
- SENSIMED Triggerfish
- Where
- Switzerland
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Glaucoma, Angle-closure
Comparing Phaco/IOL Versus Phaco/IOL + Goniosynechialysis in Subjects With PACG
The purpose of this study is to determine if phacoemulsification with intraocular lens implant (phaco/IOL) alone or combined with goniosynechialysis is better at controlling intraocular pressure in subjects with primary angle…
- Trial name
- NCT02376725
- Testing
- Phaco/IOL, Phaco/IOL + goniosynechialysis
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Vision, Healthy
Mixed Vs Blocked Search: Four Unique Tasks
The goal is to look for qualitative differences in visual search behavior when one search is performed many times in a row compared to when multiple search tasks are intermixed. Four search tasks are tested.
- Conditions
- Vision, Healthy, Attention
- Trial name
- NCT06933693
- Testing
- Mixed trials, Blocked Trials
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Visual Acuity
Ophthalmologic Examinations After Infusion of ZK200775
ZK 200775 is an antagonist at the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor and had earned attention a possible neuroprotective agent in cerebral ischemia.
- Trial name
- NCT00999284
- Testing
- ZK200775, Sodium Chloride
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Stroke, Control Condition
Vision and Proprioception Evaluation With Robotics After Stroke
Stroke is highly prevalent in Canada and can lead to profound upper limb impairments in motor and sensory function, as well and vision.
- Trial name
- VIPERS (NCT07254949)
- Where
- 2 sites in Canada
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Dr. Sean Dukelow
Alzheimer's Disease
" The Eyes Have it " : Ocular Saccade Abnormalities in Prodromal Alzheimer's Disease
Alzheimer's disease (AD) has a prolonged prodromal phase before the stage of dementia. Subtle executive cognitive function deficits can be detected at this early pre-dementia phase, more than 10 years before dementia.
- Trial name
- LYLO (NCT01630525)
- Testing
- Neuropsychological assessment, ophthalmologic checkup, Automated non-invasive oculometry
- Where
- 3 sites in France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux