Clinical trials: Visual Suppression
ART Adherence
Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)
Antiretroviral therapy (ART) has significantly decreased the morbidity and mortality of HIV infection. However, adherence challenges in taking daily oral ART persist.
- Trial name
- ROVING-PUMA (NCT06423612)
- Testing
- POC urine assay informed enhanced ART adherence counselling for viral suppression
- Where
- South Africa
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hot Flashes
Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy
This study will look at the effects of a soy supplement called Revival on memory, quality of life, and hot flashes in men with prostate cancer who are being treated with testosterone suppression therapy.
- Trial name
- NCT00245518
- Testing
- Isoflavone
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Psychometric Testing: Cued vs. Learned Suppression
In this line of research, the researchers are examining whether performance on a cued attentional suppression (ignoring) task is related to performance on a learned attentional suppression task.
- Trial name
- NCT06074523
- Testing
- Behavioral Measurement and self-report
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Appetite and Hunger, Suppression, Blood Glucose, Postprandial
Evaluation of Subjective Ratings of Appetite and Glucoregulation of a Low Calorie Diet Supplemented With a High Viscosity Polysaccharide (PolyGlycopleX - PGX)
The objective of the study is to compare subjective appetite ratings and after-meal and 24 hour blood glucose levels within overweight and obese female subjects consuming either a standardized 3 day low calorie diet supplemented…
- Trial name
- NCT01108328
- Testing
- PolyGlycopleX (PGX)
- Where
- 2 sites in Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Canadian Center for Functional Medicine
Chronic Hepatitis C Infection
Herpes Simplex Type 1 Suppression in Hepatitis C
The purpose of this study is to examine the effects of valacyclovir in patients who have chronic hepatitis C, antibodies to herpes simplex type 1 infection but do not have antibodies to herpes simplex type 2 infection.
- Trial name
- HSV1/HCV (NCT01580995)
- Testing
- Valacyclovir
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Contraception
Study of the Safety, and Sperm and Gonadotropin Suppression of a Contraceptive Gel in Normal Men
To determine the number of men who have suppression of sperm production when using a daily regimen of Nestorone® Gel (0, 8 or 12 mg) and Testosterone Gel applied transdermally.
- Trial name
- CCN007 (NCT00891228)
- Testing
- Testosterone, Nestorone®
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Premier Research
Infertility, Premature Ovarian Failure
Single Follicular Dexarelix for LH Suppression During Ovarian Stimulation in Oocyte Donors.
A randomized prospective study in the evaluation of the long acting GnRH antagonist Degarelix against the classical multidose regime with Ganirelix for LH suppression during the follicular phase of an ovarian stimulation cycle in…
- Trial name
- NCT03861715
- Testing
- live birth rate
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Preterm Contractions
Uterine Contractions Under Blue Light
The objective in the current study is to test the hypothesis that nocturnal uterine contractions in preterm women can be suppressed by brief ocular exposure to blue light.The Olcese lab at Florida State University identified a…
- Trial name
- NCT03691740
- Testing
- Ocular light
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Suppression of Ovulation
Minimal Effective Dose of Nomegestrol Acetate Inhibiting the Ovulation in Women Receiving Estradiol
The aim of the present study was to evaluate the ability of several doses of NOMAC in combination with E2 to inhibit ovulation and to assess changes in the gonadotropin and ovarian hormone profiles, in comparison to a control…
- Trial name
- NCT01361958
- Testing
- NOMAC
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Theramex
Ovulation
A Phase 2, Dose-finding, Cross-over Study to Evaluate the Effect of a NES/E2 Transdermal Gel Delivery on Ovulation Suppression in Normal Ovulating Women
This is a Phase 2, dose-finding, cross-over study for the purposes of evaluating the effect of a NES/E2 transdermal gel delivery on ovulation suppression in normal ovulating women.
- Trial name
- NCT00796133
- Testing
- NES/E2 gel
- Where
- 3 sites in United States, Chile and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Population Council
Lead, Blood, Pregnancy
Dietary Calcium Supplementation to Reduce Blood Lead in Pregnancy
Lead accumulates in bone. During pregnancy, physiologic changes occur prompting bone resorption in order to provide calcium to the growing fetal skeleton also release the lead stored in bone into a pregnant woman's circulation.
- Conditions
- Lead, Blood, Pregnancy, Bone Resorption
- Trial name
- NCT00558623
- Testing
- calcium carbonate
- Where
- Mexico
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Healthy
Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions
CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...
- Trial name
- NMCARSEHHSC (NCT02799134)
- Testing
- Dexamethasone, Vitamin C
- Where
- China
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- qinshaozheng
Malignant Neoplasm of Thyroid, Heart Diseases
Thyrotropin Over-suppression and Heart
The investigators evaluated the cardiac effects of Thyroid-stimulating hormone (TSH) over-suppression in women with differentiated thyroid cancer (DTC) frequently encountered during suppression therapy.
- Conditions
- Malignant Neoplasm of Thyroid, Heart Diseases, Thyrotoxicosis on Thyroxine Therapy
- Trial name
- NCT02645786
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
HIV, HIV Linkage to Care
Implementation Trial to Evaluate a Population Health Combination Intervention to Meet HIV Testing, Linkage, and Viral Suppression Goals in Alabama
The purpose of this study is to adapt and evaluate a combination intervention that includes: (1) a data-driven approach to directed community-based HIV testing to areas with high need, (2) Project Connect to expedite linkage to…
- Conditions
- HIV, HIV Linkage to Care, HIV Testing, HIV Treatment
- Trial name
- COAST-AL (NCT05384145)
- Testing
- COAST-AL
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Lactation Suppressed, Cabergoline Adverse Reaction
Factors and Outcomes Associated With Postpartum Cabergoline Use
Cabergoline is frequently being requested by many postpartum women with a live newborn to suppress lactation. The aim of the study is to investigate which women desire such an intervention, and what side effects they are…
- Conditions
- Lactation Suppressed, Cabergoline Adverse Reaction, Postpartum DVT, Postpartum Depression
- Trial name
- NCT03965572
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laniado Hospital
Adrenal Insufficiency
Adrenal Suppression and Adrenal Recovery Induced by Megestrol Acetate
Megestrol Acetate (MA) is a progesterone-like hormone that has been utilized as a birth control agent, chemotherapeutic drug, and more recently, to induce appetite and weight gain in patients malnourished as a result of radiation…
- Trial name
- NCT00575029
- Testing
- megestrol acetate
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Breast Cancer, Skin Cancer
Topical Fluorescent Nanoparticles Conjugated Somatostatin Analog for Suppression and Bioimaging Breast Cancer
Breast cancer is a communal malignant disease between Saudi females, with a popularity of 21.8%. Since binding to somatostatin receptors (SSTR) induces no immunogenicity in vivo, somatostatin analog (veldoreotide) (VELD) may be…
- Conditions
- Breast Cancer, Skin Cancer, Skin Diseases
- Trial name
- NCT04138342
- Testing
- Quantum dots coated with veldoreotide
- Where
- 4 sites in Egypt, Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
HIV/AIDS
VITAL Start: Brief Facility-based Video Intervention
This a multi-center, parallel group, randomized controlled outcome assessor blinded trial with a qualitative descriptive component that seeks to assess the effectiveness of a brief facility-based video intervention to optimize…
- Trial name
- VITAL (NCT03654898)
- Testing
- VITAL Start: Video-based pre-ART counseling, Standard of Care
- Where
- Malawi
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Respiration Disorders
Validation of RespiLife for Detection of Respiratory Suppression
The purpose of this study is to evaluate the accuracy of RespiLife diagnostic technology for detection of respiratory rate and oxygen saturation in human subjects.
- Trial name
- NCT03819023
- Testing
- Respilife monitor
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bioresp Technologies, Inc.
HIV Seropositivity
Hybrid Type I Effectiveness-Implementation Trial of a Social Network Support Intervention
The goal of this Hybrid Type I effectiveness-implementation trial is to test an evidence-based, flexible, and tailored intervention that leverages existing social network members to promote retention in care and viral suppression…
- Trial name
- NCT05723653
- Testing
- Social Network Support Intervention
- Where
- 7 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Chicago