Clinical trials: Vital Pulp Therapy
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Dental Caries Extending to Pulp, Molar Incisor Hypomineralization
Vital Pulp Therapy in Carious Teeth With Hypomineralization
Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth.
- Trial name
- NCT03735069
- Testing
- IPT (Indirect pulp treatment), Cvek/partial pulpotomy, Cervical pulpotomy
- Where
- Jordan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Irreversible Pulpitis
Comparative Effectiveness in the Management of Irreversible Pulpitis
This project addresses a central question within the practice of dentistry: Is a pulpotomy procedure effective in the treatment of a tooth with symptomatic irreversible pulpitis and normal periapex? In addition, the project seeks…
- Trial name
- NCT04922229
- Testing
- RCT, Pulpotomy
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Necrotic Pulp With Symptomatic Apical Periodontitis
The Impact of Using Different Final Irrigation Modes on Postoperative Pain Following Root Canal Treatment of Non-vital Mandibular First Molar With Periapical Lesion.
The goal of this clinical trial is to learn which rinsing of root canals method works best to lower pain after a root canal in adults.
- Trial name
- NCT07623629
- Testing
- root canal treatment
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Deep Caries, Pulpitis Reversible
The Prognostic Impact of Symptoms and Lesion Depth in Partial Removal of Carious Tissue
The goal of this prospective, observational clinical cohort study is to study the effect of the preoperative condition of the tooth on the outcome of partial removal of carious tissue in mature teeth in adults.
- Conditions
- Deep Caries, Pulpitis Reversible, Pulp Hyperemia
- Trial name
- NCT05816525
- Testing
- Partial removal of carious tissue, Final restoration
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Reversible Pulpitis, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Pulpotomy in Teeth with Different Symptoms and Root Stages
Pulpotomy is a vital pulp therapy (VPT) method used to maintain pulp vitality by removing inflamed or infected coronal pulp tissue while preserving the health and function of radicular pulp.
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Mature Teeth, Immature Teeth
- Trial name
- NCT06874088
- Testing
- Pulpotomy with Calcium Silicate-Based Bioceramics in Permanent Teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Muhammed Alagöz
Irreversible Pulpitis
Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars
Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.
- Trial name
- NCT06613932
- Testing
- pulpotomy
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Pulpotomy
Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars
Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars
- Trial name
- NCT06640205
- Testing
- pulpotomy
- Where
- Egypt
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Anesthesia, Local
Pain Control of Needle-free Versus Needle Injected Local Anesthesia for Pulpotomy of Upper Primary Molars in Children
This is a study that will be conducted on 6 to 8 years old children to compare the needle-less jet injector with the conventional needle attached syringe in terms of efficiency in controlling pain of local anesthetic infiltration…
- Trial name
- NCT03917121
- Testing
- Jet injector, Needle attached dental syringe
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries Extending to Pulp, Pulp Disease, Dental
Assessment of Vital Pulp Therapy in Permanent Molars
The purpose of this study is to evaluate the long term clinical performance of vital pulp therapy of young permanent teeth with irreversible pulpitis
- Trial name
- NCT03410134
- Testing
- NeoMTA
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Pulpitis - Irreversible
Pulpotomy vs Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
This study is a randomised controlled trial for complete pulpotomy as an alternative to root canal treatment for teeth with clinical diagnosis of symptomatic irreversible pulpitis (i.e.
- Trial name
- NCT05964933
- Testing
- Complete Pulpotomy, Pulpectomy and Root Canal Treatment
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Irreversible Pulpitis
Comparing MTA Pulpotomy to Root Canal Treatment in Management of Permanent Molars With Irreversible Pulpitis in Children
Dental caries, highly prevalent amongst children, can cause pulpitis. Coronal pulpotomy provides an easier, cost-effective, conservative and biologically-driven treatment option compared to endodontic treatment in mature…
- Trial name
- NCT06488131
- Testing
- MTA Pulpotomy, Root Canal Treatment
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulpitis Reversible
Clinical, Radiographic and Patient Acceptance Evaluation of LASER Compared to Formocresol Pulpotomies inPrimary Molars
The goal of this clinical trial was to compare the clinical and radiographic success of laser versus formocresol pulpotomy in primary molars.
- Trial name
- NCT06200818
- Testing
- Diode laser, Er:CrYSGG, Formocresol
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Impacted Third Molar Tooth
Conventional Coronectomy vs Coronectomy in Combination Vital Pulp Treatment Using Calcium Silicate
The aim of this study was to compare the conventional coronectomy and the combined coronectomy technique with vital pulp treatment.
- Trial name
- NCT05882162
- Testing
- Coronectomy, Pulp Capping with calcium silicate
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- zeynep cukurova yilmaz
Pulp and Periapical Tissue Disease
Regenerative Endodontics for Non-vital Primary Molars
Non-vital primary molars will be treated with regenerative endodontic idea using different capping materials aiming to replace the necrotic pulp tissue with biological one and to provide perfect seal over the scaffold
- Trial name
- NCT05098483
- Testing
- Regeneration in primary molars by using MTA, Regeneration in primary molars by using biodentine, Conventional Root canal treatment in primary molars
- Where
- Egypt
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vital Pulp Therapy
Comparative Evaluation of Three Pulpotomy Agents for Permanent Mature Molars With Irreversible Pulpitis
Statement of the problem: Accurate pulpal diagnosis is essential for decision making between vital pulp therapy and root canal treatment.
- Trial name
- NCT06232941
- Testing
- Full pulpotomy procedure
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vital Pulp Therapy
Effect of Topical Dexamethasone on Histologic Response of Human Dental Pulp
Abstract Aim The aim of this randomized clinical trial was to histologically investigate possible effects of dexamethasone application on pulp tissue healing during one step mineral trioxide aggregate (MTA)-direct pulp capping…
- Trial name
- NCT02574468
- Testing
- Dexamethasone applied on pulp or Dexamethasone did not applied on pulp, DPC or MP
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Pulpitis - Irreversible
Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis
This study will compare the outcome of partial and miniature pulpotomy in mature permanent molars with symptomatic partial irreversible pulpitis
- Trial name
- NCT05406557
- Testing
- Partial pulpotomy, Miniature pulpotomy
- Where
- India
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontic Inflammation, Pulp Disease, Dental
Evaluation of Clinical and Radiological Success of Vital Amputation Treatment
Total amputation therapy; is a treatment method aimed at maintaining the vitality of the radicular pulp remaining as a result of complete removal of coronal pulp tissue.
- Trial name
- NCT03883295
- Testing
- Control, NeoMTA Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University