Clinical trials: Vitamin B-12 Deficiency
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Vitamin B 12 Deficiency
Oral/Intramuscular B12 to Treat Cobalamin Deficiency
Objective: To determine the effectiveness of oral versus intramuscular Cobalamin (vitamin B12) by restore cobalamin parameter in blood at 8, 26 and 52 weeks in ≥ 65 aged patients with Cobalamin Deficiency.
- Trial name
- OB12 (NCT01476007)
- Testing
- oral Cobalamin (vitamin B12), intramuscular Cobalamin (vitamin B12)
- Where
- Spain
- Volunteers
- 284 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Mild Cognitive Impairment, Dementia
COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE
This retrospective study is a more extensive, confirmatory analysis of the cognitive and functional outcomes initially seen in 2 groups of MCI/dementia patients in Springfield, MA and compares specialized dementia care and a…
- Conditions
- Mild Cognitive Impairment, Dementia, Hypoxia, Hyperhomocysteinemia
- Trial name
- NCT02860338
- Volunteers
- 900 people
- Sponsor
- Clionsky Neuro Systems Inc.
Iron Deficiency, Vitamin A Deficiency
Nutritional Status and Bouillon Use in Northern Ghana
This pilot aims to generate data that are critical for informing the design of a planned, more detailed study to evaluate the effect of multiple micronutrient (MN)-fortified bouillon cube on biomarkers of nutrient status of women…
- Conditions
- Iron Deficiency, Vitamin A Deficiency, Vitamin B 12 Deficiency, Folate Deficiency
- Trial name
- NCT04632771
- Testing
- N/A (observational study)
- Where
- Ghana
- Volunteers
- 995 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Vitamin B12 Deficiency
Can Recombinant Human Intrinsic Factor Be Used for Evaluation of the Vitamin B12 Absorption?
Vitamin B12 is an essential nutrient for normal DNA-synthesis and must be supplied by animal products. Vitamin B12 deficiency may cause anemia and irreverible neurological damage.
- Trial name
- NCT00279552
- Testing
- Recombinant human intrinsic factor
- Where
- Denmark
- Volunteers
- 37 people
- Sponsor
- University of Aarhus
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Nitrous Oxide Abuse, Subacute Combined Cord Degeneration
Neurological Recovery Following NOS-SACD
Nitrous oxide has become an increasingly popular recreational drug amongst young people, particularly at festivals, nightclubs and parties.
- Conditions
- Nitrous Oxide Abuse, Subacute Combined Cord Degeneration, Neurologic Symptoms, Paresthesia
- Trial name
- NCT05714917
- Testing
- Observational study with no interventions
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Cognitive Change, Nutrient Deficiency
Nutrition, Vision, and Cognition in Sport Study: Beef
The purpose of this study is to determine whether a 30 day beef intervention can improve peak cognitive performance in young, normally menstruating adult women.
- Conditions
- Cognitive Change, Nutrient Deficiency, Nutritional Anemia, Visual Spatial Processing
- Trial name
- IONSport:Beef (NCT04427852)
- Testing
- 30 day Daily consumption of 1 serving of beef, 30 day Daily consumption of 1 serving of the vegatable protein source
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Anemia, Folate Deficiency
Quadruple Fortified Salt Trial in India
Women of reproductive age are at an increased risk of anemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of neural tube defects and other pregnancy complications.
- Conditions
- Anemia, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- QFS (NCT03853304)
- Testing
- + Folic acid, + Vitamin B12, DFS
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cornell University
Vitamin B12 Deficiency
Holotranscobalamin Remains Unchanged During Pregnancy
Background and objective: Plasma cobalamins decrease during pregnancy but it is not fully elucidated how this is reflected in the total and cobalamin saturated transport proteins, transcobalamin (total TC, holoTC) and haptocorrin…
- Trial name
- NCT00467623
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Vitamin D Deficiency, B12 Deficiency Vitamin
Relationship Between Vitamin D and Vitamin B12 Levels and Neuropathic Pain in Lipedema
Lipedema is a disease characterized by bilateral abnormal fat deposition in the upper and lower extremities. Pain is a common symptom in lipedema.Vitamin D plays an important role in chronic pain.
- Conditions
- Vitamin D Deficiency, B12 Deficiency Vitamin, Lipedema
- Trial name
- NCT06338059
- Testing
- Vitamin B12 Level
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Vitamin B12 Deficiency
Relative Bioavailability of Folic Acid and L-5-Methlytetrahydrofolate
Folic acid, a form of the vitamin folate, is added to grain products in Canada to help reduce birth defects. Folic acid is the synthetic form of folate and is very stable (doesn't break down) when added to foods.
- Trial name
- NCT01584050
- Testing
- L-5-methyltetrahydrofolate (Metafolin ®), folic acid
- Where
- 2 sites in Canada, Malaysia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Vitamin B 12 Deficiency
Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation
Vitamin B12, a vital nutrient, plays a crucial role in red blood cell formation, neurological function, and DNA synthesis. Deficiency in B12 can lead to anemia, neurological symptoms such as tingling or numbness, and cognitive…
- Trial name
- NCT06376591
- Testing
- Vit B12
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
B12 Deficiency Combined With C677T Mutation on MTHFR Gene
Examining B12 Deficiency Associated With C677T Mutation on MTHFR Gene in Terms of Commonness and Endothelial Function
The purpose of this study is to determine the commonness of the C677T mutation in the MTHFR gene in subjects with B12 deficiency.
- Trial name
- NCT00730574
- Testing
- Vitamin B12 + Folic Acid
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Moshe Flugelman
Muscle Strength, Vitamin B 12 Deficiency
Study of the Association of Muscle Strength, Balance and Other Factors With Vitamin Levels Among Elderly Diabetics
Vitamin B12 deficiency can cause severe problems with the blood, nerves, brain and psychological well-being. Ironically, our modern methods for the control of diabetes mellitus can actually contribute to vitamin B12 deficiency.
- Conditions
- Muscle Strength, Vitamin B 12 Deficiency, Folate Deficiency, Vitamin D Deficiency
- Trial name
- NCT03376490
- Where
- Singapore
- Volunteers
- 56 people
- Sponsor
- SingHealth Polyclinics
Vitamin B 12 Deficiency
Cobalamin Supply and Metabolism in Healthy Children From Birth to the Age of 12 Months and in Their Mothers (Cbl_Neo)
Introduction: Infants with severe vitamin B12 (cobalamin, Cbl) deficiency can develop severe, sometimes irreparable neurological damage in the first months of life.
- Trial name
- Cbl_Neo (NCT05315843)
- Where
- 2 sites in Austria, Germany
- Volunteers
- 160 people
- Sponsor
- University Children's Hospital, Zurich
COVID, Zinc Deficiency
Evaluation of the Relationship Between Zinc Vitamin D and b12 Levels in the Covid-19 Positive Pregnant Women
Zinc d vitamin and b12 serum levels in covid-19 positive pregnants will be compared in terms of patients' responses to computed tomography and treatment.
- Conditions
- COVID, Zinc Deficiency, Vitamin D Deficiency
- Trial name
- NCT04407572
- Testing
- Serum zinc, vitamin d vitamin b12 levels .
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Cobalamin Deficiency
Effect of Toothpaste Fortified With Cyanocobalamin on Vitamin B12 Status
A 3 months randomized, placebo-controlled study on the effect of toothpaste fortified with vitamin B12 on vitamin B12 status markers and related metabolic markers.
- Trial name
- NCT02679833
- Testing
- Cyanocobalamin
- Where
- 2 sites in Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Vitamin B12 Deficiency
Vitamin Deficiencies and Suppletion in Morbid Obesity
The purpose of this study is to evaluate the most effective treatment for patients who underwent a Roux-en-Y gastric bypass and developed postoperatively a vitamin B12 deficiency.
- Trial name
- NCT02270749
- Testing
- Hydroxocobalamin, FitForMe vitamin B12
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Vitamin d Deficiency, Vitamin B 12 Deficiency
ETOL-Elderly Study of the Efficiency of the Innovative Food Supplement in Elderly Adults
The aim of this pilot study is to conduct a study on geriatric population in Slovenia (non-users of dietary supplements/medicines with vitamine D, vitamin B12 and protein) and assess deficiency of selected nutrients, and to…
- Conditions
- Vitamin d Deficiency, Vitamin B 12 Deficiency, Protein Deficiency
- Trial name
- ETOL-Elderly (NCT05661006)
- Testing
- Use of food supplement
- Where
- Slovenia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)