Clinical trials: Vitamin B-12 Deficiency
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Vitamin B 12 Deficiency
Cobalamin Supplementation During Infancy; Effect on B-vitamin Status, Growth and Psychomotor Development
Adequate levels of vitamin B12 (cobalamin) is necessary for normal growth and development in infants. We have earlier investigated cobalamin status in healthy children and we observed metabolic evidence of impaired cobalamin…
- Trial name
- NCT00479479
- Testing
- Hydroxycobalamin (Vitamin B12 Depot, Nycomed Pharma)
- Where
- Norway
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Vitamin B12 Deficiency
Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients
Vitamin B12 has several important functions in the body, two of which are production of red blood cells and the maintenance of a healthy nervous system. When vitamin B12 is deficient, abnormal red blood cells form.
- Trial name
- NCT01876732
- Testing
- Vitamin B12
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Northwell Health
Obesity, Bariatric Surgery
Effectiveness of a Modified Cost-Effective Dietary Plan in Promoting Weight Loss and Preservation of Lean Body Mass in Patients After Bariatric Surgery
This study will see if a low-cost dietary plan, based on the standard dietary guidelines of the American Society for Metabolic and Bariatric Surgery (ASMBS) and using locally available foods, can help patients lose weight and…
- Conditions
- Obesity, Bariatric Surgery, Nutritional Status, Body Composition
- Trial name
- NCT07111767
- Testing
- Low-Cost Post-Bariatric Diet, Standard High-cost Post-Bariatric Diet
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Khyber Teaching Hospital
Vitamin B12 Deficiency
Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
A review of the literature reveals that very few studies have assessed the potential co-existence of vitamin B12 deficiency due to gastric parietal cell autoantibodies. While Segal et al.
- Trial name
- NCT01876329
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Keesler Air Force Base Medical Center
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Vitamin B12 Deficiency
How Many Patients Are in Need of Vitamin B12 Injections?
The clinical consequences of vitamin B12 deficiency include megaloblastic anemia and neurological disorders. Therefore, a proper and timely diagnosis and treatment is important.
- Trial name
- NCT00326833
- Testing
- vitamin B12
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
End Stage Renal Disease on Dialysis, Vitamin B 12 Deficiency
Vitamin B12 Status and Its Impact on Chronic Haemodialysis Patient
To evaluate vitamin B12 level in haemodialysis patients and its impact on hematological and neurological manifestations
- Trial name
- Haemodialysis (NCT06441721)
- Testing
- Vitamin b12 measure
- Volunteers
- 60 people
- Sponsor
- Assiut University
Type 2 Diabetes, Vitamin B12 Deficiency
Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin
The purpose of this project is to compare two pharmacist-led population management strategies designed to increase the rate of appropriate monitoring of vitamin B12 and serum creatinine for patients taking metformin.
- Conditions
- Type 2 Diabetes, Vitamin B12 Deficiency, Neuropathy, Anemia
- Trial name
- NCT02076347
- Testing
- Office visit intervention, Electronic Message Intervention
- Where
- United States
- Volunteers
- 489 people
- Sponsor
- Ohio State University
Vitamin B12 Deficiency, Type 2 Diabetes Mellitus
Metformin Use and Vitamin B12 Deficiency
The primary objective is to determine the incidence of Vitamin B12 deficiency in patients on metformin therapy for diabetes.
- Trial name
- NCT01136512
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Obesity, Morbid, Homocystine; Metabolic Disorder
Homocysteine After Laparoscopic Roux-enY Gastric Bypass
Changes in homocysteine values after bariatric surgery remain controversially discussed. This is the first comprehensive summary to depict timeline changes in homocysteine levels following laparoscopic roux-en-Y gastric bypass.
- Conditions
- Obesity, Morbid, Homocystine; Metabolic Disorder, Bariatric Surgery Candidate, Folate Deficiency
- Trial name
- NCT03489538
- Testing
- laparoscopic long limb roux-en-Y gastric bypass
- Where
- Austria
- Volunteers
- 708 people
- Sponsor
- Medical University of Vienna
Anemia, Folate Deficiency
Periconceptional Surveillance in India
Women of reproductive age are a high-risk population for anaemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of adverse pregnancy complications.
- Conditions
- Anemia, Folate Deficiency, Vitamin B12 Deficiency
- Trial name
- NCT04048330
- Where
- India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Cornell University
Nutritional Status, Nutrient Deficiency
Dietary Challenges in the Population of Nursing Homes' Residents
To obtain up-to-date data on nutritional status of older adults, a national dietary survey will be conducted in 2022/2023, providing data on the consumption of foods and enabling the assessment intakes of energy and specific…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NUTRICARE (NCT05389618)
- Testing
- Diagnostic Tests
- Where
- Slovenia
- Volunteers
- 300 people
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency)
Supplementation of Critical Nutrients in a Plant-based Diet
500 participants of the vegan/vegetarian congress VegMed are to be included, which should answer once (cross-sectional study) a medicine socio-behaviorist questionnaire on the topic "supplementation of critical nutrients in a…
- Conditions
- Deficiency, Vitamin, Vegan's Anemia (Vitamin B12 Deficiency), Deficiencies Micronutrient
- Trial name
- NCT03542591
- Testing
- Questionnaire on the topic "Supplementation of critical nutrients in a plant-based diet"
- Where
- Germany
- Volunteers
- 500 people
- Sponsor
- Charite University, Berlin, Germany
Hyperhomocysteinemia, Hyperlipoproteinemias
Evaluating the Impact of B Vitamin Supplementation (Soloways™) on Homocysteine and LDL-C Levels in Patients With MTHFR, MTR, and MTRR Polymorphisms.
This randomized, double-blind, placebo-controlled trial will evaluate the impact of methylfolate, pyridoxal-5'-phosphate (P5P), and methylcobalamin supplementation on homocysteine and LDL-C levels in individuals with low to…
- Trial name
- VITAGEN-H (NCT06163443)
- Testing
- Vitamin B
- Where
- Russia
- Volunteers
- 54 people
- Sponsor
- S.LAB (SOLOWAYS)
Vitamin B 12 Deficiency
A Comparison of Two Different Doses of Maternal B12 Supplementation in Improving Infant B12 Deficiency and Neurodevelopment
Supplementation with Iron and folate have been part of a worldwide strategy targeting anaemia and neural tube defects for many years. However, vitamin B12 deficiency has received much less attention.
- Trial name
- MATCOBIND (NCT04083560)
- Testing
- Vit B12
- Where
- 2 sites in India, Nepal
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- Sitaram Bhartia Institute of Science and Research
Vitamin B 12 Deficiency, Type 2 Diabetes Mellitus (T2DM)
Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients
This randomized, double-blind, placebo-controlled clinical trial aims to evaluate the effectiveness of Sucrosomial® Vitamin B12 supplementation in the management of vitamin B12 deficiency among metformin-treated Type 2 Diabetes…
- Trial name
- NCT06983223
- Testing
- Sucrosomial® Vitamin B12
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Anemia in Pregnancy, Preeclampsia
A Retrospective Analysis of Neevo®/Neevo®DHA Compared to a Standard Prenatal Vitamin in Anemia During Pregnancy
This study is a multi-site, retrospective chart review to determine the effect of Neevo® or Neevo®DHA (with higher folate and B12) versus standard prenatal vitamins on hemoglobin (Hgb) levels in pregnant women throughout the…
- Trial name
- NCT01062958
- Testing
- Neevo® (a medical food), Prenatal vitamins (≤1mg folic acid, 27 - 35mg iron, and ≤12mcg vitamin B12)
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pamlab, Inc.