Clinical trials: Vitrectomy
Rhegmatogenous Retinal Detachment of Both Eyes (Diagnosis)
Characters of Epiretinal Membranes in Patients With Previous Vitrectomy for Retinal Detachment
31 patients were included in the study,15 cases with ERM in silicone filled eyes and 16 eyes with idiopathic ERM
- Trial name
- RD (NCT04288440)
- Testing
- Surgery, Vitrectomy machine
- Where
- Egypt
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Tanta University
Vitrectomy
Analgesic Effect and Safety of Oliceridine and Oxycodone in Vitrectomy
Traditional opioid analgesia is a method to treat moderate to severe pain. However, the use of opioids is not without risks. When treating acute pain, patients may have hypotension, respiratory depression, hypoxia, nausea and…
- Trial name
- NCT07097038
- Testing
- Oliceridine, Oxycodone
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Epiretinal Membrane
27-gauge Vitrectomy Wound Integrity: a Prospective, Randomized Trial Comparing Angled Versus Straight Entry
To prospectively compare clinical outcomes using straight (perpendicular) versus angled trocar insertion during 27 gauge pars plana vitrectomy surgery for epiretinal membrane Primary Endpoints: Sclerotomy suture rates and…
- Trial name
- NCT02836210
- Testing
- 27-gauge vitrectomy wound construction
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Macular Holes
MSC-Exos Promote Healing of MHs
Purpose: To assess the safety and efficacy of mesenchymal stem cells (MSCs) and MSC-derived exosomes (MSC-Exos) for promoting healing of large and refractory macular holes (MHs).
- Trial name
- MSCs (NCT03437759)
- Testing
- exosomes derived from mesenchymal stem cells (MSC-Exo)
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Pain
Intravitreal Injection Site and Perceived Pain
The objective of this study is to explore the perception of pain during intravitreal injection related to the distance of the entry site from the limbus.
- Trial name
- NCT05640895
- Testing
- Intravitreal injection site
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Vitrectomy, Cataract
Objective Measurements of the Opacification of the Lens After Vitrectomy
Cataract is the opacification of the lens. Usually cataract occurs slowly, causing progressive vision loss over several months or years.
- Trial name
- MOCVIT (NCT04566237)
- Testing
- Objective Scatter Index (OSI), Average Lens Density (ALD)
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Endolaser or Encircling Band for Rhegmatogenous Retinal Detachment
Comparing primary PPV with 360° endolaser photocoagulation with primary PPV with an encircling band for patients with RRDs.
- Conditions
- Rhegmatogenous Retinal Detachment, Primary Vitrectomy, Encircling Band, Endolaser Treatment
- Trial name
- NCT00757536
- Testing
- Encircling Band, Endolaser Photocoagulation
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Retinal Edema
Suprachoroidal Injection of Triamcinolone Acetonide in Resistant Diabetic Macular Edema, CRVO, Pseudophakic Cystoid Macular Edema and Diabetic Macular Edema Following Pars Plana Vitrectomy
Prospective interventional study on 60 eyes of resistant diabetic macular edema and central retinal vein occlusion that will receive suprachoroidal injection of Triamcinolone Acetonide (SCTA).
- Trial name
- Resistant (NCT04690608)
- Testing
- Triamcinolone Acetonide 40Mg/Ml Inj,Susp_#1
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tanta University
Epiretinal Membrane, Macular Edema
A Pilot Study of the Effectiveness of Intra-operative Ozurdex® in Vitrectomy Surgery for Epiretinal Membranes
To determine if an intravitreal sustained release dexamethasone implant (Ozurdex®) injected at the conclusion of surgery in patients undergoing vitrectomy and membrane peeling for idiopathic epiretinal membranes is safe and…
- Trial name
- NCT01701518
- Testing
- Ozurdex
- Where
- 2 sites in Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
No Disease or Condition is Being Studied
Optimizing Operational Parameters for Diagnostic Vitrectomy
Single-center ex-vivo study using blood samples from healthy donors processed through a 25-gauge vitrectomy system. The study compares four combinations of operational parameters (vacuum pressure and cut rate) to evaluate their…
- Trial name
- CELLVIT (NCT07408466)
- Testing
- Simulated vitrectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Rhegmatogenous Retinal Detachment
Healaflow Patch for the Treatment of Rhegmatogenous Retinal Detachment
To report the surgical results of primary rhegmatogenous retinal detachment (RRD) repaired by 27G pars plana vitrectomy (PPV) combined with Healaflow patch and air tamponade, and do not need prone position postoperation.
- Trial name
- NCT03542162
- Testing
- Healaflow
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Nuclear Sclerotic Cataract
Comparison of Scheimpflug Photos of the Crystalline Lens in Patients Who Have Undergone Vitrectomy Surgery and Controls
Progression of nuclear sclerotic cataract after pars plana vitrectomy has been recognized for many years The mechanism for the rapid progression of nuclear sclerotic cataract remains unclear.
- Trial name
- NCT00406263
- Testing
- Scheimpflug crystalline lens photographs
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Barnes Retina Institute
Proliferative Diabetic Retinopathy
Endolaserless Vitrectomy With Intravitreal IAI for PDR-Related VH
This is a phase I/II open label, randomized, interventional clinical trial. Study eyes will receive one preoperative intravitreal aflibercept injection (IAI) <21 days but >7 days prior to vitrectomy and one intraoperative IAI at…
- Trial name
- LASERLESS (NCT02976012)
- Testing
- Aflibercept, Endolaserless Vitrectomy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Southeast Retina Center, Georgia
Macular Edema, Epiretinal Membrane
Intravitreal Dexamethasone Implant for Persistent Macular Thickening and Edema After Vitrectomy for Epiretinal Membrane
This study seeks to evaluate the effect of the intravitreal 0.7mg dexamethasone implant on central macular thickness and visual acuity in those patients with persistent macular edema after pars plana vitrectomy for epiretinal…
- Conditions
- Macular Edema, Epiretinal Membrane, Vitrectomy
- Trial name
- DEMO (NCT02995746)
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Rhegmatogenous Retinal Detachment
Dropless Pars Plana Vitrectomy Study
To demonstrate that intraoperative use of subtenon triamcinolone acetonide at the time of surgery without postoperative eye drops is non-inferior to the regimen of postoperative eye drops following primary pars plana vitrectomy…
- Trial name
- DVS (NCT05331664)
- Testing
- Pars plana vitrectomy, Triamcinolone Acetonide 40mg/mL, Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Vitrectomy
Beveled-Tip Versus(vs) Standard-Tip Vitrectomy Probe
The purpose of this study is to compare the efficiency of the new Utravit High-Speed 10000 cpm Beveled Probe to the current standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm.
- Trial name
- NCT04076072
- Testing
- Utravit High-Speed 10000 cpm Beveled Probe, standard vitrector probe- Alcon (non-beveled) Ultravit 7500 cpm
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center