Clinical trials: Vitreous Detachment
Proliferative Vitreoretinopathy, Rhegmatogenous Retinal Detachment
Effects of 0.1% Nepafenac on Vitreous Inflammatory Biomarkers in Rhegmatogenous Retinal Detachment and Proliferative Vitreoretinopathy
PVR remains the major cause of surgical failure in RRD repair.1 Prompt surgical management is the standard therapy in RRD repair.
- Trial name
- NCT07162818
- Testing
- Nepafenac 0.1% eyedrops
- Where
- Indonesia
- Volunteers
- 61 people
- Sponsor
- Universitas Indonesia
Macular Hole, RPE Detachment
Comparison of a Spectral OCT/SLO With the Stratus OCT for Imaging Various Retinal Pathologies
The purpose of this study is to compare the newly released Spectral OCT/SLO (OTI, Toronto, Canada) with the Zeiss Stratus OCT (Carl-Zeiss Meditec, Dublin, CA) with regards to the quality of the images obtained as well as the ease…
- Conditions
- Macular Hole, RPE Detachment, Epiretinal Membrane, Posterior Vitreous Detachment
- Trial name
- NCT00408720
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The New York Eye & Ear Infirmary
Vitreomacular Adhesion
Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older
The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.
- Trial name
- VAST (NCT02160340)
- Where
- 18 sites in United States
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Neovascular Age-related Macular Degeneration
Intravitreal Ranibizumab in Exudative Age-related Macular Degeneration With Posterior Vitreomacular Adhesion
The main objective is to determine the efficacy of intravitreal administration of Ranibizumab combined with intravitreous injection of expansile gas and induction of posterior vitreous detachment on best-corrected visual acuity…
- Trial name
- NCT01291121
- Testing
- Intravitreal expansile gas and ranibizumab injection
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Anterior Uveitis (AU), Birdshot Chorioretinitis
Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of…
- Conditions
- Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus
- Trial name
- NCT07065747
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Vitreous Detachment
YAG Laser Vitreolysis for Floaters
Vitreous fluid, containing 95% water, fills the space behind the lens. Its gelatinous consistency is due to the presence of hyaluronic acid, mucopolysaccharide and collagen fibers.
- Trial name
- NCT03970148
- Testing
- Nd: YAG laser
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital of Split
Retina Detachment, Eye Injuries
Multi-center Clinical Observation of FCVB in Guangdong Province
This study provides further theoretical guidance for clinical application of FCVB through observing and collecting various indicators before and after surgical treatment of the FCVB in the real world.
- Conditions
- Retina Detachment, Eye Injuries, Eye Atrophy, Silicone Emulsion
- Trial name
- NCT03908515
- Testing
- Foldable Capsular Vitreous Body (FCVB)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Proliferative Diabetic Retinopathy
A Study of the Safety, Tolerability, and Efficacy of IVT Pre-op 0.3mg Pegaptanib Sodium Versus Sham, for Management of Tractional Retinal Detachment and Vitreous Hemorrhage With Proliferative Diabetic Retinopathy
The purpose of this study is to assess whether preoperative pegaptanib sodium safely improves vitreous hemorrhage prior to surgical intervention and to evaluate the stability of pre-existing tractional retinal detachment.
- Trial name
- No-Crunch01 (NCT01589718)
- Testing
- Macugen
- Where
- United States
- Sponsor
- Greater Houston Retina Research
Traction Retinal Detachments, Rhegmatogenous Retinal Detachments
Vitreous Surgery With Intraocular Assistance
To Assess the Safety of Vitreous surgery with intraocular assistance (VISIA) \& to identify and document with video evidence and surgeon's case report forms intraocular maneuvers that are facilitated by VISIA.
- Conditions
- Traction Retinal Detachments, Rhegmatogenous Retinal Detachments, Dislocated Intraocular Lens
- Trial name
- VISIA (NCT02574624)
- Testing
- Intraocular assistance
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Vitreous Detachment
Comparison of Propofol Target Controlled Infusion (TCI) and Sevoflurane
This study was an experimental, single-blinded, randomized controlled trial that aimed to compare recovery time between TCI propofol and sevoflurane.
- Trial name
- NCT04865991
- Testing
- TCI Propofol, Sevoflurane
- Where
- Indonesia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Vitreoretinal Traction Syndrome
Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment
Plasmin is expected to create a posterior vitreous detachment. The pharmacological creation of a posterior vitreous detachment may be beneficial in a variety of conditions.
- Trial name
- NCT00348439
- Testing
- Plasmin, Vehicle
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Bausch & Lomb Incorporated
Diabetic Vitreous Hemorrhage, Tractional Retinal Detachment
Assessment of Retinal Vascular Changes With and Without ILM Peeling in Diabetic Vitrectomy Using OCT-A.
Tractional retinal detachment (TRD) that involves the macula and non-clearing vitreous hemorrhage are the main causes of permanent vision loss in patients with diabetic retinopathy and requires prompt surgical intervention.
- Trial name
- NCT05739539
- Testing
- optical coherence tomography angiography, spectral domain optical coherence tomography
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kasr El Aini Hospital
Diabetic Retinopathy
A Safety and Efficacy Study of Vitreosolve® for Non-Proliferative Diabetic Retinopathy Subjects
The purpose of this study is to determine the safety and efficacy of Vitreosolve® in diabetic retinopathy patients.
- Trial name
- NCT00908778
- Testing
- Vitreosolve
- Where
- 5 sites in India, Mexico
- Volunteers
- 160 people
- Sponsor
- Vitreoretinal Technologies, Inc.
Optic Disc Pit Maculopathy
Vitrectomy for Optic Disc Pit Maculopathy
The purpose of this study is to evaluate the efficacy of vitrectomy, without gas tamponade or laser photocoagulation to the margin of the optic nerve, for the treatment of macular detachment associated with optic disc pits and to…
- Trial name
- NCT01340703
- Testing
- vitrectomy without laser or gas tamponade
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Kyorin University
Posterior Vitreous Detachment, Diabetic Retinopathy
Annular Array Ultrasound in Ophthalmology
The objective of this research is to improve the care of ocular disease and disorders, in particular the changes in the eye associated with diabetes, by providing clinicians with dramatically improved ultrasonic images of the…
- Trial name
- NCT01415037
- Testing
- annular array ultrasound exam
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Columbia University
Retinal Detachment, Refractive Errors
Refractive Changes Following Vitrectomy
We aimed o compare the refractive changes associated with pars plana vitrectomy with or without intraocular gas tamponade in pseudophakic eyes.
- Conditions
- Retinal Detachment, Refractive Errors, Vitreous Hemorrhage, Epiretinal Membrane
- Trial name
- NCT04712786
- Testing
- pars plana vitrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Bursa Retina Eye Hospital
Vitreoretinal Traction Syndrome
A Study to Evaluate Plasmin for the Creation of a Posterior Vitreous Detachment (PVD)
Plasmin is expected to create a posterior vitreous detachment (PVD) when injected directly into the eye. The pharmacological creation of a PVD may be beneficial in helping to treat a variety of conditions.
- Trial name
- NCT00347646
- Testing
- Plasmin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Bausch & Lomb Incorporated
Diabetic Retinopathy, Retinal Detachment
Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA)
The purpose of this study is to compare the amount of intraoperative intraocular bleeding during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD) with and without preoperative intravitreal…
- Trial name
- IBETRA (NCT00690768)
- Testing
- Bevacizumab, pars plana vitrectomy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
Intravitreal Triamcinolone and Biomarkers in Rhegmatogenous Retinal Detachment
This prospective, randomized, controlled clinical study evaluates the effects of preoperative intravitreal triamcinolone acetonide (TA) on growth factors and inflammatory mediators in patients with rhegmatogenous retinal…
- Trial name
- NCT07774182
- Testing
- Standard Vitrectomy, Triamcinolone acetonide (TA)
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Anggun Rama Yudantha
Posterior Vitreous Detachment
Incidence of Complete Posterior Vitreous Detachment After Trabeculectomy.
Intraocular surgery could induce vitreous degeneration and posterior vitreous detachment (PVD). Vitreomacular interface (VMI) abnormalities usually are caused by abnormal PVD, vitreoschisis and partial-thickness PVD.
- Trial name
- NCT04726267
- Testing
- Wide-field optical coherence tomography
- Where
- Thailand
- Volunteers
- 46 people
- Sponsor
- Khon Kaen University