Clinical trials: Volume
Acute Respiratory Distress Syndrome ARDS
Driving Pressure-guided Tidal Volume Ventilation in the Acute Respiratory Distress Syndrome
Acute respiratory distress syndrome (ARDS) is associated with high mortality, some of which can be attributed to ventilator-induced lung injury (VILI) when artificial ventilation is not customized to the severity of lung injury.
- Trial name
- DRIVENT (NCT06322758)
- Testing
- Tidal volume customization in the acute respiratory distress syndrome
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Breast Cancer
Do Skin Markings Reflect the Location of the Surgical Cavity During Daily Radiotherapy Treatment?
Markings placed on the skin are an accurate representation of the underlying surgical cavity and are adequate to use for patient setup for accelerated partial breast irradiation.
- Trial name
- NCT00578747
- Where
- 2 sites in Canada
- Volunteers
- 21 people
- Sponsor
- British Columbia Cancer Agency
Post Induction Hypotension
Comparing the Hemodynamic Effects of Volume Loading vs Non-loading During Induction of Anesthesia in Fluid Responder Patients With Coronary Artery Disease Undergoing Elective Coronary Artery Bypass Graft Surgery: a Randomized Controlled Study.
All preoperative cardiac medications will be continued till the morning of the surgery, except angiotensin converting enzyme inhibitors.
- Trial name
- NCT05462847
- Testing
- Ringer acetate
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Kasr El Aini Hospital
Pulmonary Emphysema
Unilateral Versus Bilateral Endoscopic Lung Volume Reduction A Comparative Case Study
Patients with bilateral heterogeneous pulmonary emphysema benefit to differing degrees from unilateral ELVR with complete lobe closure in comparison with incomplete bilateral treatment.
- Trial name
- NCT00995852
- Testing
- IBV Implantation
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Heidelberg University
Interscalene Block, Shoulder Arthroscopy
Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade
The main aim of the study is to investigate the proven effect of dexamethsone on the duration of the interscalene block. The investigators try to define optimal dose and volume for ropivacaine, when used together with…
- Conditions
- Interscalene Block, Shoulder Arthroscopy, Dexamethasone, Low Volume Regional Anesthesia
- Trial name
- NCT02178449
- Testing
- Dexamethasone acetate, Ropivacaine
- Where
- 2 sites in Austria
- Volunteers
- 109 people
- Sponsor
- Landesklinikum Sankt Polten
Recession, Gingival
Influence of Connective Tissue Graft Around Implants
The objective of this randomized controlled clinical study was to evaluate the increase in the volume of peri-implant gingival tissue in implants installed in the aesthetic areas with the use of subepithelial-conjunctive tissue…
- Trial name
- NCT03106506
- Testing
- Connective tissue graft
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Fracture of Hip
Hemodynamic Monitoring and Resuscitation in Hip Fractures
Background: Fracture of the hip is a potentially fatal event in an elderly, frail, highly comorbid patient group suffering from dehydration and hypovolemia, and it carries a risk that equals major trauma in young patients in…
- Trial name
- NCT03401138
- Testing
- Preoperative Stroke Volume(SV)-guided fluid optimization
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Hvidovre University Hospital
Moderate or Severe Mitral Regurgitation
Novel 3-dimensional Echocardiographic Quantification of Mitral Regurgitant Volume
The goal of this observational study is demonstrate that a novel artificial intelligence based software for the quantification of the mitral regurgitation on 3-dimensional transesophageal echocardiography (3D CFQ) is more…
- Trial name
- AIM_3D (NCT07528781)
- Testing
- analysis of the performance of an artificial intelligenced based software for analysis of 3D tranesophageal echocardiography data
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Germans Trias i Pujol Hospital
Emphysema
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study)
The purpose of this research is to study an investigational medical device that is designed to produce lung volume reduction in diseased areas of the lungs in patients with severe emphysema.
- Trial name
- LIBERATE (NCT01796392)
- Testing
- EBV, Optimal Medical Management
- Where
- 23 sites in United States, Brazil and 2 more
- Volunteers
- 190 people
- Sponsor
- Pulmonx Corporation
Hemodynamic Monitoring
Goal-directed Hemodynamic Therapy in Patiens Undergoing Major Hepatic Resection
The aim of the study of patients undergoing major hepatic resection was compared standard perioperative (control Group) with hemodinamic management based on PPV, VVS, continuos CO trending and dynamic arterial elastance using…
- Trial name
- GOAL-HEMO (NCT04517409)
- Testing
- Goal-directed hemodynamic therapy, Control
- Volunteers
- 45 people
- Sponsor
- Castilla-La Mancha Health Service
Surgery, Pneumoperitoneum
Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Laparoscopy
During pneumoperitoneum insufflation the insufflated gas increase intra-abdominal pressure. The generated pressure can lead to a different increase in volume depending on the abdominal cavity and patients' characteristics.
- Conditions
- Surgery, Pneumoperitoneum, Intra Abdominal Pressure
- Trial name
- NCT04468698
- Testing
- Peritoneum insufflation
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Hospital Universitario La Fe
Emphysema
Endoscopic Lung Volume Reduction Coil Treatment in Patients With Chronic Hypercapnic Respiratory Failure
Endoscopic lung volume reduction coil treatment is a treatment option for selected patients with severe emphysema. In the advanced stages, emphysema may lead to chronic hypercapnic respiratory failure.
- Trial name
- NCT02996149
- Testing
- Endoscopic lung volume reduction coil treatment
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dorsal Hand Volume Loss
A Study of YVOIRE Y-Solution 360 for Hand Augmentation to Correct Volume Loss
The purpose of this study is to evaluate the effectiveness and safety of YVOIRE Y-Solution 360 in the treatment of dorsal hand to correct volume loss.
- Trial name
- NCT04112017
- Testing
- YVOIRE Y-Solution 360
- Where
- 2 sites in South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- LG Chem
Non-small Cell Lung Cancer
Predictive Value of FDG PET/CT, DWI and DCE-MRI Scans for Non-small Cell Lung Cancer Patients Receiving Chemotherapy
In this prospective study, the investigators will evaluate and compare the usefulness of functional and volumetric informations obtained by 18F-FDG PET and MRI before and after the palliative chemotherapy with the aim of…
- Trial name
- NCT01482182
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Samsung Medical Center
Respiratory Insufficiency
Pressure-limited Ventilation Versus Volume-targeted Ventilation in Term Newborns
A randomised controlled trial comparing volume-targeted ventilation to pressure-limited ventilation in infants born at or near term.
- Trial name
- NCT02358460
- Testing
- Ventilation delivered by SLE5000 ventilator
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- King's College London
Free Gingival Graft, Free Gingival Graft Volume Change
Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant
Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues.
- Conditions
- Free Gingival Graft, Free Gingival Graft Volume Change, Keratinized Tissue
- Trial name
- NCT06645925
- Testing
- One Step Protocol, Two Steps Protocol
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Misr International University
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Native Lung Overinflation in Patients That Underwent Single Lung Transplantation Due to Emphysema
The Value of Bronchoscopic Lung Volume Reduction by Endobronchial Valves in Patients With Single Lung Transplantation and Overinflation of the Native Lung
The purpose of the study is to investigate if bronchoscopic lung volume reduction by valves (Zephyr) would reduce native lung overinflation in patients that underwent single lung transplantation due to emphysema, and improve…
- Trial name
- NCT01682018
- Testing
- lung volume reduction using the Zephyr device
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Rabin Medical Center
Underdosing of Local Anesthetics
Minimum Effective Volume Of Local Anesthetic İn USG Guided Axillary Approach Brachial Plexus Block
Background Peripheral nerve blocks with use of USG allowed visualisation of the structures and nerves and made the block administrations safe, quick and comfortable.
- Trial name
- NCT02837718
- Testing
- bupivakain % 0,5
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
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