Clinical trials: Vomiting
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Motility Disorder, Gastroparesis
Body Surface Gastric Mapping to Evaluate Patients With Upper Gastrointestinal Symptoms and Controls
This is an analytical validation observational cohort study is designed to provide evidence of: safety and reliability of Body Surface Gastric Mapping using the Gastric Alimetry System (GAS), normal reference values, and…
- Conditions
- Motility Disorder, Gastroparesis, Functional Dyspepsia, Cyclical Vomiting
- Trial name
- NCT05812339
- Testing
- Gastric Alimetry System
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy Volunteers
Study to Assess Safety and Tolerability of KarXT With Administration of Antiemetics in Healthy Volunteers
This study looks at how to reduce nausea and vomiting in people taking KarXT which is used to treat mental health conditions like schizophrenia.
- Trial name
- NCT07681076
- Testing
- KarXT, Trimethobenzamide, Ondansetron
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV)
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
- Conditions
- Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV), Postoperative Nausea and Vomiting
- Trial name
- NCT07868861
- Testing
- NS003 Ondansetron HCl microspheres powder for nasal application, Ondansetron Solution for IV infusion 8mg
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Vomiting, Nausea
Inhaled Isopropyl Alcohol for Treatment of Nausea
To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.
- Conditions
- Vomiting, Nausea, Children, Only
- Trial name
- NCT05418244
- Testing
- Inhaled Isopropyl Alcohol, Oral Ondansetron
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Chemotherapy-Induced Nausea and Vomiting (CINV)
QLM2010 Comparative Pharmacokinetic Study With 2-Minute Intravenous Administration
This is a single-center, single-dose, randomized, open-label, crossover study. Forty-two healthy male and female participants will be enrolled.
- Trial name
- NCT07817004
- Testing
- apripitant and palonosetron injectable emulsion, palonosetron hydrochloride injection, apripitant injection (CINVANTI)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Qilu Pharmaceutical (Hainan) Co., Ltd.
Local Application/Packing Too Cold, Patient Satisfaction
The Effect of Cold Application on Nausea and Vomiting in the Early Postoperative Period
As a result of the literature review, it has been seen that it has not yet been clarified whether cold application methods are effective on postoperative nausea and vomiting, and academic studies on this subject are needed.
- Conditions
- Local Application/Packing Too Cold, Patient Satisfaction, Postoperative Nausea and Vomiting
- Trial name
- NCT05888818
- Testing
- Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Postoperative Nausea and Vomiting, Bowel Functions
Menthol Chewing Gum After Laparoscopic Colorectal Surgery
This randomized controlled trial was conducted to evaluate the effect of menthol chewing gum on postoperative nausea and vomiting, bowel function, and recovery in patients undergoing laparoscopic colorectal surgery.
- Conditions
- Postoperative Nausea and Vomiting, Bowel Functions, Postoperative Recovery
- Trial name
- NCT07796529
- Testing
- Menthol Chewing Gum
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Postoperative Nausea and Vomiting, Scoliosis
A Comparison Between Palonosetron Versus Granisetron as PONV Prophylaxis in Scoliotic Patients Undergoing Spine Surgery
The aim of this clinical trial is to compare the effectiveness of two Serotonin (5- HT3) receptor antagonist, palonosetron and granisetron, administered along with dexamethasone as a preventive measure against early and delayed…
- Trial name
- PONV (NCT06540885)
- Testing
- Palonosetron (Group P), Granisetron (Group G)
- Where
- 2 sites in Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cyclic Vomiting Syndrome
Cortical Excitability in Cyclic Vomiting Syndrome
This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain…
- Trial name
- NCT05256160
- Testing
- TMS Paired-Pulse assessment of cortical excitability, Autonomic activity
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Nausea and Vomiting Syndrome
Brain-Stomach Circuits in Chronic Nausea
The goal of this study is to determine whether stimulation of the brain-stomach connection can influence stomach activity in healthy adults and in individuals suffering from chronic nausea.
- Trial name
- NCT07276035
- Testing
- Transcranial Magnetic Stimulation, TMS
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- David Levinthal
Postoperative Pain, Acute, Postoperative Nausea and Vomiting
The Impact of Breath Exercise Training on Postoperative Pain, Anxiety, and Nausea-Vomiting in General Surgery Patients
This study was conducted to determine the effect of breath exercise on post-operative anxiety level, pain, and nausea-vomiting after general surgery. This was a randomized, controlled experimental study.
- Conditions
- Postoperative Pain, Acute, Postoperative Nausea and Vomiting, Patient Relations, Nurse
- Trial name
- NCT06546514
- Testing
- Breath Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Hyperemesis Gravidarum
Hyperemesis Gravidarum Risk Reduction With Metformin
The goal of this clinical trial is to evaluate whether daily oral metformin extended-release (metformin-XR), taken prior to and in early pregnancy, can reduce the risk and severity of Hyperemesis Gravidarum (HG), a severe nausea…
- Trial name
- NCT07129473
- Testing
- Metformin Extended Release Oral Tablet
- Where
- 2 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Vomiting, Postoperative, Pain
Association Between Pain Catastrophizing and PONV in Laparoscopic Cholecystectomy Patients
This study aims to explore whether patients' tendency to exaggerate or focus on pain (pain catastrophizing) is related to experiencing nausea and vomiting after surgery.
- Conditions
- Vomiting, Postoperative, Pain, Nausea and Vomiting, Postoperative, Pain Catastrophizing
- Trial name
- NCT07712211
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Postoperative Nausea and Vomiting, Anesthesia Complication
Risk Factors for Postoperative Nausea and Vomiting (PONV) in Adults at the Post-Anaesthesia Care Unit of Dr. Cipto Mangunkusumo National General Hospital
The goal of this observational study is to determine the incidence of postoperative nausea and vomiting (PONV) and identify its risk factors in adult patients recovering in the post-anaesthesia care unit (PACU) after elective…
- Conditions
- Postoperative Nausea and Vomiting, Anesthesia Complication, Postoperative Complication
- Trial name
- PONV-RSCM (NCT07688811)
- Testing
- Routine perioperative anaesthesia care
- Where
- Indonesia
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Emesis
The Antiemetic Effects of Increased Splanchnic Perfusion, Induced by the Gut Hormone GIP, in Healthy Individuals
This study investigates whether the gut hormone glucose-dependent insulinotropic polypeptide (GIP) can reduce feelings of nausea.
- Trial name
- GIP EMESIS (NCT07687589)
- Testing
- Glucose-dependent Insulinotropic Polypeptide (GIP), GLP-1 (7-36) amide, Apomorphine Injectable Solution
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Postoperative Nausea and Vomiting
PONV Prevention Via Percutaneous Nerve Electrical Stimulation on PC6
This study aims to certify the effectiveness of percutaneous electrical nerve stimulation at Pericardium 6 (PC6) via a wearable equipment during perioperative period on preventing postoperative nausea and vomiting.
- Trial name
- NCT06241547
- Testing
- electrical stimualtion via EmeTerm bracelet, antimetic drugs（ dexamethasone，ondansetron）
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Gastroparesis
GI Neuromuscular Pathology Prospective Registry
In this research study, biopsy samples will be collected to provide more insight into the underlying cause of the motility disorders, help direct further investigation into the cause of the underlying condition, provide future…
- Trial name
- NCT02165059
- Testing
- Surgical Full Thickness Biopsy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Post Operative Pain, Nausea and Vomiting, Postoperative
ENDOblock: Bilateral Superficial Cervical Blocks With Local Wound Infiltration in Thyroid Surgery
This is a single center, prospective, double-blinded randomized controlled trial comparing the efficacy of bilateral superficial cervical plexus blocks (BSCPB) with local wound infiltration vs placebo with local wound…
- Conditions
- Post Operative Pain, Nausea and Vomiting, Postoperative, Opioid Use
- Trial name
- NCT05805423
- Testing
- bilateral superficial cervical plexus blocks and local wound infiltration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Davis