Clinical trials: WOUNDS INJURIES
Acute Respiratory Syndrome Distress, Positive End-Expiratory Pressure
EIT-Guided PEEP Optimization in Trauma and Postoperative ARDS
Acute respiratory distress syndrome (ARDS) remains a serious and often fatal complication in patients following severe trauma or major surgery.
- Conditions
- Acute Respiratory Syndrome Distress, Positive End-Expiratory Pressure, Electrical Impedance Tomography, Trauma and Postoperative Pulmonary Insufficiency
- Trial name
- EIT-PEEP-SURG (NCT07313644)
- Testing
- EIT-giuded PEEP, Control
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Nguyen Dang Thu
Trauma Injury
Effect of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block
Effect of intravenous dexmedetomidine versus dexamethasone for management of repound pain after supraclavicular brachial plexus block.
- Trial name
- NCT06304909
- Testing
- Dexmedetomidine injection, Dexamethasone, Saline
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fracture
Risk Taking and Fracture Study
Boys suffer a disproportionately large number of fractures compared to girls (55-60%). This study aims to determine why this is the case by identifying risk factors for wrist fractures.
- Trial name
- NCT01768598
- Testing
- Fracture - Boys, Fracture - Girls, Non Fracture - Boys
- Where
- 2 sites in Canada
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Canadian Institutes of Health Research (CIHR)
Injury, Training
Evaluation of a Resident Curriculum in Firearm Injury Prevention
The purpose of this project is to evaluate the efficacy of a web-based curriculum designed to teach pediatric practitioners how to provide injury prevention anticipatory guidance, emphasizing firearm injury prevention in a clinic…
- Trial name
- NCT01027104
- Testing
- Education
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Distal Radius Fracture
Assessing Volar Locking Plates in Patients Under 65 With a Distal Radius Fracture
Patients will be randomized to volar plating with early ROM versus closed reduction with K-wires and 6 weeks of cast immobilization to determine if there is any advantage to volar plating in this subgroup of patients with distal…
- Trial name
- DRF (NCT01333371)
- Testing
- Surgical Repair of Distal Radius Fracture
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Hand and Upper Limb Clinic, Canada
Unstable Intertrochanteric Hip Fractures
INTUIT Hip Fracture Outcome Study
The primary objective of this study is to characterize patients' course of recovery in the year following the initial surgery for unstable intertrochanteric hip fractures treated with the InterTAN intramedullary hip screw device.
- Trial name
- INTUIT (NCT00595634)
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Smith & Nephew, Inc.
Wounds and Injuries, Cancer Pain
Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds
The goal of this clinical trial is to compare in compare pain reduction in patients with malignant wounds using morphine gel or lidocaine gel.
- Conditions
- Wounds and Injuries, Cancer Pain, Cancer, Breast, Cancer Head Neck
- Trial name
- MorphineGEL (NCT05800834)
- Testing
- Morphine Sulfate, Lidocaine Hcl 2% Jelly
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Open Fracture
Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections
This is a prospective, single-center, double-blind randomized clinical trial aimed at evaluating the efficacy and safety of the extended-release antibiotic device, STIMULAN, in preventing infections in patients with open…
- Trial name
- NCT06033534
- Testing
- STIMULAN
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Università Vita-Salute San Raffaele
Injuries, Patellofemoral Pain Syndrome
Effect of Strength and Coordination Training on Biomechanics and Injury in New Runners
The investigators hypothesize that new runners participating in an 8 week strength and coordination training program prior to beginning to run will 1) display different coordination patterns , and 2) experience fewer injuries…
- Conditions
- Injuries, Patellofemoral Pain Syndrome, Iliotibial Band Syndrome
- Trial name
- NCT03293121
- Testing
- Strength and Coordination Training, Walking
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Shoulder Surgery, Shoulder Pain
Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block
This prospective observational study aims to evaluate the incidence of hemidiaphragmatic paralysis in patients receiving interscalene brachial plexus nerve block with prolonged neural blockade.
- Conditions
- Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
- Trial name
- NCT04209504
- Testing
- Ultrasound, Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Proximal Femur Fractures, Nerve Block Assessment
Comparison Of Preoperative Ultrasound Guided Fascia Iliaca Block Versus Femoral Nerve Block for Proximal Femur Fractures Before Positioning for Spinal Anaesthesia
Proximal femur fractures are among the most painful orthopedic injuries Adequate analgesia is essential to facilitate positioning for spinal anesthesia, reduce opioid requirements, and minimize related complications.
- Trial name
- NCT07716358
- Testing
- Femoral Nerve Block, Fascia Iliaca Nerve Block
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Sahara Medical College Narowal Pakistan
Brain Injuries
The DECRA Trial: Early Decompressive Craniectomy in Patients With Severe Traumatic Brain Injury
This is a multi-centre randomised trial to evaluate the effect of early decompressive craniectomy on neurological function in patients with severe traumatic brain injury.
- Trial name
- NCT00155987
- Testing
- Early decompressive craniectomy
- Where
- Australia
- Volunteers
- 155 people
- Sponsor
- National Trauma Research Institute
Facial Injuries
Structural Fat Grafting for Craniofacial Trauma Using Manual Technique for Processing Fat Graft Material
This study will examine the impact of the fat grafting procedure on facial appearance and quality of life over time by precisely measuring soft tissue volume with CT scans, assessing appearance with 2D and 3D photography and…
- Trial name
- BTI++ (NCT02267187)
- Testing
- Fat Grafting, General Anesthesia, Coleman Cannulas
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Pittsburgh
Tennis Elbow, Lateral Epicondylitis
Comparison of Two Different Treatment Effects on Individuals With Chronic Lateral Epicondylitis
The aim of this study is to compare the effects of Radial Extracorporeal Shockwave Therapy (rESWT) treatment and Deep Friction Massage (DFM) treatment on pain, functionality, grip strength (GS), edema, range of motion (ROM) of…
- Conditions
- Tennis Elbow, Lateral Epicondylitis, Tendinopathy
- Trial name
- NCT04187287
- Testing
- Radial Extracorporeal Shock Wave Therapy, Deep Friction Massage
- Where
- Cyprus
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Spinal Cord Injuries
Posttraumatic Changes in Energy Expenditure and Body Composition in Patients With Acute Spinal Cord Injury
Severe trauma induces massive metabolic changes that are characterized by hypermetabolism with increased energy expenditure and catabolism.
- Trial name
- NCT01980784
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Traumatic Brain Injury, Deep Vein Thrombosis
Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
Whilst deep vein thrombosis (DVT) is common following traumatic brain injury (TBI), optimal timing and safety of pharmacological prophylaxis is uncertain. Paradoxically the harm associated with the occurrence of is also unclear.
- Conditions
- Traumatic Brain Injury, Deep Vein Thrombosis, Acute Lung Injury, Ventilator Associated Pneumonia
- Trial name
- TARDIS (NCT03937947)
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- NHS Lothian
Spinal Cord Injury
Wheelchair Mobility Assessment of Individuals With Spinal Cord Injury
The specific aims of this study are: 1) to assess the test-retest reliability of a modification of an existing wheelchair propulsion assessment and 2) validate the modification against traditional measures of physical strength…
- Trial name
- NCT01204047
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Miami
Hypotension, Brain Injuries
Correlation Between Circulating Biomarkers of Organs Damage and Intraoperative Hypotension Management
Intraoperative hypotension (defined as mean arterial pressure below 65 mmHg) is associated with increased organs dysfunction and mortality.
- Conditions
- Hypotension, Brain Injuries, Renal Failure, Endothelial Dysfunction
- Trial name
- NCT03527758
- Testing
- Flo TracIQ with HPI software
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Catania
Ankle Injuries
Turkish Version of the Ankle Instability Instrument
This study aimed to translate the Ankle Instability Instrument into Turkish language, to perform a cultural adaptation study and to evaluate its validity and reliability in the Turkish population.
- Trial name
- NCT04816058
- Testing
- Determining the level of ankle instability
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Lateral Epicondylitis, High Intensity Laser Therapy
High and Low Dose High-intensity Laser Therapy Lateral Epicondylitis
High-intensity laser therapy has gained increasing attention in recent years as a therapeutic modality. It is a non-invasive treatment that can reduce pain, increase local blood circulation, and promote tissue repair.
- Conditions
- Lateral Epicondylitis, High Intensity Laser Therapy, Tennis Elbow, High Intensity Laser
- Trial name
- NCT07342426
- Testing
- High intensity laser therapy, Infarred ray therapy system, Transcutaneous electrical nerve stimulator
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
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