Clinical trials: Walking Impairment
Mild Cognitive Impairment
Effects of Single and Dual Task Training in Individuals With Mild Cognitive Impairment
The aim of this study is to compare the effects of single and dual-task training on processing speed, cognitive functions, walking speed, dual-task performance and balance functions in individuals with mild cognitive impairment.
- Trial name
- NCT04301960
- Testing
- Single task training, Dual task training
- Where
- Cyprus
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Mobility Limitation, Cognitive Impairment
Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance…
- Trial name
- NCT03122236
- Testing
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Active Transcranial Direct Current Stimulation (Active tDCS)
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Mild Cognitive Impairment
Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI
Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria.
- Trial name
- NCT06935812
- Testing
- Bimanual Exercise, Finger Exercise, Virtual Reality
- Where
- Cyprus
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Caregiver Burden, Depression
Neighborhood-based Physical and Social Activity for Older Black Caregivers and People Living With Dementia
The Sharing History through Active Reminiscence and Photo-imagery (SHARP) Program engages triads (primary caregiver, person living with dementia, caregiver support person) in walking and social reminiscence, using a group tablet…
- Conditions
- Caregiver Burden, Depression, Cognitive Impairment
- Trial name
- SHARP-CG (NCT05658328)
- Testing
- SHARP - Physical and social activity
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson Disease, Healthy Aging
ParKinWalk: Physical Activity and Long Group-walking for Parkinson's Disease
The study will evaluate the impact of exercise training program followed by long-walking onon supervised and unsupervised gait assessment in Parkinson´s disease and control subjects.
- Trial name
- ParKInWalk (NCT04266782)
- Testing
- Exercise program followed by long walk in group, Exercise program followed by long walk in group (controls)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Brescia
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Reaction Time, Physical Fitness
Comparison of Physical Fitness, Walking Speed, Reaction Time In Older Adults With and Without Mild Cognitive Impairment
The aim of the study is to compare physical fitness, walking speed and hand reaction time measurements in older adults with different cognition levels according to the Montreal Cognitive Assessment Scale (MOCA).
- Trial name
- NCT05472727
- Testing
- reaction time test, Physical fitness test
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Cognitive Impairment, Aging
Influence of Overground Walking on Biomarkers, Cognitive Function, and Quality of Life in Elderly With Mild Cognitive Impairment
The purpose of this research is to investigate the impact of overground walking as a part of a rehabilitation program on the increase in Brain-derived neurotrophic factor (BDNF) levels, decrease in IL-6 levels, decrease in hs-CRP…
- Trial name
- NCT06029920
- Testing
- Overground Walking
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Mild Cognitive Impairment
Study of Motor Representations in Healthy Subjects and Amnestic MCI
Walking, Brain and Functional Magnetic Resonance Imaging Study of motor representations in healthy subjects and amnesic MCI.
- Trial name
- IRMARCHE (NCT02574182)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Lung Cancer
Pulmonary and Extrapulmonary Impairments in Patients With Lung Cancer Awaiting Surgery
To detect comparatively the extent to which physical impairments are observed in patients with lung cancer awaiting lung surgery, comparing exercise capacity, pulmonary functions, muscle strength, physical activity, dyspnea…
- Trial name
- NCT04450719
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Gazi University
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Peripheral Arterial Disease
Locomotion and Global Positioning System in Arterial Disease
The maximal walking distance (MWD) performed on treadmill (TT) remains the gold standard in estimating the walking capacity of patients suffering from peripheral arterial disease (PAD) with intermittent claudication, although…
- Trial name
- Starter-GPS (NCT00485147)
- Testing
- Recording of GPS during a free walking in a public park
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Severe Mobility Impairment, Spinal Cord Injuries (SCI)
Effects of Virtual Walking on Chronic Pain and Psychological Distress for Individuals With Severe Mobility Impairment
This randomized controlled trial aims to: (1) examine the effects of virtual walking intervention on chronic pain (primary outcome), and on depression, stress, anxiety, and quality of life (secondary outcomes) compared with the…
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (SCI), Poliomyelitis
- Trial name
- NCT07820618
- Testing
- Virtaul walking, Passive observing video
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Multiple Sclerosis
Trekking Poles to Aid Multiple Sclerosis Gait Impairment
In this study, the investigators will examine a sample of persons with multiple sclerosis (MS) to determine whether their walking function and ability is different depending on which walking assistive device is used.
- Trial name
- TRAMS (NCT02227524)
- Testing
- No device, Single-point cane (SPC), Four-point cane (FPC)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Rowan University
Cognitive Impairment
Walking Interventions, Cognitive Remediation and Mild Cognitive Impairment
The purpose of this study is to determine the effects of a coordinated intervention of cognitive remediation training (CRT) and walking intervention on cognition and gait in the elderly.
- Trial name
- WalkCog-MCI (NCT01801943)
- Testing
- Cognitive Remediation Therapy Group, Walking Intervention (WI) Group, Combination Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Aging, Parkinson Disease
Beam Walking Across the Lifespan for Falls Prediction
Background: Dynamic balance keeps the vertical projection of the center of mass within the base of support while the center of mass moves. The age-related decrease in dynamic balance is a risk factor for falls.
- Conditions
- Aging, Parkinson Disease, Stroke, Dementia
- Trial name
- BEAM (NCT03532984)
- Testing
- Beam test to predict falls
- Where
- 5 sites in Brazil, Germany and 3 more
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Healthy, Thalamic Pain Syndrome
Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
A large proportion of falls in older people occurs when walking. Most studies have recently demonstrated correlation between the variations in spatiotemporal gait parameters and fall risk in elderly and in several diseases.
- Conditions
- Healthy, Thalamic Pain Syndrome, Fallers
- Trial name
- GAITRITE (NCT01443052)
- Testing
- Gait analysis
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Typically Developing Children, Talipes Equino Varus
Measuring Normal and Impaired Walking in Children Using the GAITRite Walkway
Walking measurement in children is important but there are challenges associated with obtaining reliable repeatable data in a clinical setting that is meaningful and easy to interpret.
- Conditions
- Typically Developing Children, Talipes Equino Varus, Paediatric Orthopaedic, Paediatric Neurological
- Trial name
- NCT05571501
- Testing
- Gait assessment using the GAITRIte walkway
- Where
- United Kingdom
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust