Clinical trials: Water
Dehydration, Head & Neck Cancer
DRIHNC - Dehydration Reduction in Head & Neck Cancer
The purpose of this study is to decrease the rate of visits to the Emergency Department (ED) and Acute Care Clinics (ACC) for dehydration for head \& neck (H\&N) and esophageal cancer patients that are given Gatorade while…
- Conditions
- Dehydration, Head & Neck Cancer, Esophageal Cancer
- Trial name
- NCT03799380
- Testing
- Gatorade G2, Standard of care nutritional support
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Case Comprehensive Cancer Center
Healthy
Pain Inhibitory Effects of Other Pain Induced by Mechanical Pressure Compared to Electrical Stimulation and Cold Water.
The objective is to estimate the effects on pain thresholds of a painful mechanical stimulus on the upper trapezius compared to a painful electrical stimulus and a diffuse noxious stimulus using the cold water hand immersion test.
- Trial name
- NCT05730127
- Testing
- Conditioning stimulus
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Josue Fernandez Carnero
Hookah Smoking, Secondhand Aerosol
Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol
In the United States, secondhand smoke is the third leading preventable cause of death. Flavored hookah (waterpipe) tobacco smoking, a highly social activity common in hookah bars, is a key source of SHS exposure.
- Conditions
- Hookah Smoking, Secondhand Aerosol, Vascular Stiffness, Vaping
- Trial name
- NCT04661683
- Testing
- Combustible Hookah Smoke, Electronic Hookah Aerosol, Clean Room Air
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy
24-Week Water Aerobics Program for Adults and Older Adults at Different Intensity Levels
This goal of this clinical trial is to verify the best way to do water aerobics with adults and older adults. It wants to answer these questions: Is high-intensity water aerobics better than water aerobics performed at moderate…
- Trial name
- NCT06529354
- Testing
- Moderate-intensity Group, High-intensity Group
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beira Interior
Massive Hemorrhage, Trauma
Calcium Administration in Life-saving Management During Massive Hemorrhage
This study evaluates the feasibility of conducting a larger study on the impact of treating massive hemorrhage with calcium in trauma patients.
- Conditions
- Massive Hemorrhage, Trauma, Hypocalcemia
- Trial name
- CALM (NCT06820645)
- Testing
- calcium gluconate
- Volunteers
- 81 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Irritant Contact Dermatitis Due to Incontinence, Diaper Rash
Comparison of Wash Wipes and Standard Care in the Prevention of Incontinence-associated Dermatitis in Elderly
Incontinence is a widespread problem in all health care setting. One of the main complications of incontinence is inflammation of the skin in the genital and anal region, also known as incontinence-associated dermatitis (IAD).
- Conditions
- Irritant Contact Dermatitis Due to Incontinence, Diaper Rash, Pressure Ulcer, Incontinence-associated Dermatitis
- Trial name
- NCT02475512
- Testing
- Wash wipes (3M), water and pH neutral soap
- Where
- 11 sites in Belgium
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy Participants
A Study to Evaluate the Study Medication (Etrasimod) When Mixed With Food in Healthy Participants
The purpose of this study is to compare how healthy adults process Etrasimod when taken in different forms. One form is Etrasimod taken without food. The other form is Etrasimod mixed with water and 3 different foods.
- Trial name
- NCT05956002
- Testing
- Estraimod Immediate Release (IR), Etrasimod Mini Tab in water, Etrasimod Mini Tab in chocolate pudding
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
DiGeorge Anomaly, DiGeorge Syndrome
Thymus Transplantation Dose in DiGeorge #932
One purpose of this study is to determine whether the amount of cultured thymus tissue implanted into DiGeorge anomaly infants has any effect on the immune outcome.
- Conditions
- DiGeorge Anomaly, DiGeorge Syndrome, Complete DiGeorge Anomaly, Complete DiGeorge Syndrome
- Trial name
- NCT00576836
- Testing
- Cultured Thymus Tissue Implantation (CTTI), Cultured Thymus Tissue Implantation with Parathyroid Transplantation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Sumitomo Pharma Switzerland GmbH
Urologic Diseases, Urinary Tract Infections
Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients
This is a single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa care (Komplexní lázeňská léčebně rehabilitační péče, KLP) on patients with nephrological and urological conditions treated at a spa…
- Conditions
- Urologic Diseases, Urinary Tract Infections, Nephrolithiasis, Nephrocalcinosis
- Trial name
- Uro-Nefro (NCT07435844)
- Testing
- Comprehensive Spa Care, Exercise Therapy, Dietotherapy
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Hyponatremia, Syndrome of Inappropriate ADH (SIADH) Secretion
An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH
This is a retrospective chart review non-interventional study designed to collect real world data on the use and outcomes of tolvaptan for the treatment of patients with hyponatraemia secondary to syndrome of inappropriate…
- Trial name
- SAMPLE (NCT02545101)
- Where
- 7 sites in Germany, Spain
- Volunteers
- 100 people
- Sponsor
- Otsuka Pharmaceutical Europe Ltd
Osteoporosis, Osteopenia
Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
The purpose is to perform a one-year study designed to assess whether treatment of hypovitaminosis D increases intestinal absorption of calcium, subsequent retention of calcium within bone, decreases bone turnover, and favorably…
- Conditions
- Osteoporosis, Osteopenia, Vitamin D Deficiency, Hypoparathyroidism
- Trial name
- NCT00581828
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sunscreening Agents
Clinical Study to Evaluate the 80-Minute Water Resistant Sun Protection Factor (SPF) of Sunscreen Products
The purpose of this study is to determine the 80-Minute Water Resistant SPF of three sunscreen products (ChapStick Active Performance [CAP] UnScented, CAP Herbal Mint Flavour and CAP Mountain Berry Flavour) using the methodology…
- Trial name
- NCT05124899
- Testing
- CAP UnScented, CAP Herbal Mint, CAP Mountain Berry
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- HALEON
Pulmonary Congestion
Thoracic Fluid Assessment by Contrast-enhanced Magnetic Resonance Imaging and Bioimpedance
Heart failure (HF) is a major health problem, which is characterized by reduced cardiac function leading to pulmonary congestion. Most episodes of acute HF requiring unplanned hospitalization are due to pulmonary congestion.
- Trial name
- NCT02364193
- Testing
- MRI, Gd-CA, BIS ImpediMed™ SFB7
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Waterpipe Smoking
The Role of Contingency Management in Waterpipe Smoking Cessation
Tobacco use kills more than 500,000 people in the United States each year. Although the use of cigarettes has declined, the use of other tobacco products has remained steady.
- Trial name
- NCT02159092
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Washington State University
Healthy
A Water Consumption Study of ALKS 5461 in Healthy Volunteers
This study will evaluate the impact of water consumption on the pharmacokinetics of ALKS 5461.
- Trial name
- NCT02521857
- Testing
- ALKS 5461
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Heart Failure, Diabetic Kidney Disease
Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study
This study evaluates the safety of finerenone compared with alternate-day spironolactone in patients with heart failure and diabetic kidney disease at increased risk of hyperkalemia.
- Conditions
- Heart Failure, Diabetic Kidney Disease, Hyperkalemia
- Trial name
- SAFE-K (NCT07523867)
- Testing
- Finerenone, Spironolactone (drug)
- Volunteers
- 60 people
- Sponsor
- Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Small Bowel Obstruction, Contrast Media Adverse Reaction
Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction
The goal of this prospective observational study is to evaluate the diagnostic and therapeutic utility of an enteral contrast challenge for pediatric patients with adhesive small bowel obstruction (ASBO). The aims are to 1.
- Trial name
- SBO (NCT06101719)
- Testing
- Enteral contrast challenge
- Where
- 9 sites in United States
- Volunteers
- 136 people
- Sponsor
- Children's Hospital Colorado
Water Intake
A Three-Group Study to Examine the Efficacy of the Air up® Drinking System at Improving Hydration and Associated Health Outcomes
A randomized, controlled trial evaluating the air up® drinking system's impact on hydration and health outcomes. Participants will use air up® with Peach, Orangeade, or unscented pods and their effects on drinking habits, and…
- Trial name
- NCT06290479
- Testing
- Air Up® Peach Pod, Air Up® Orangeade Pod
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- air up GmbH
Patients on Hemodialysis for More Than 3 Months
Extravascular Lung Water Monitoring by Combined Ultrasound and Bioimpedance as a Guide for Treatment in Hemodialysis Patients
Patients will be selected from the Dialisys Centers in Iasi, Romania. Patients will be randomized 1:1 to have a dry-weight assessment based on clinical (control) or lung US and bioimpedance (active) guided protocol.
- Trial name
- BUST (NCT01815762)
- Testing
- Active arm
- Where
- Romania
- Volunteers
- 250 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Cushing Disease Due to Increased ACTH Secretion
Combination Osilodrostat and Cabergoline in Cushing's Disease
Cushing disease remains a challenging endocrine disorder in which persistent or recurrent hypercortisolism often requires medical therapy after surgery or when surgery is not feasible.
- Trial name
- COSCA-ECD (NCT07603466)
- Testing
- osilodrostat, osilodrostat and cabergoline
- Where
- 5 sites in Iraq
- Volunteers
- 50 people
- Sponsor
- University of Basrah
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