Clinical trials: Water
Hyponatremia, Dilutional Hyponatremia
Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia
The purpose of this study is to determine if hospitalized patients with symptomatic hyponatremia treated with tolvaptan are in the hospital for less time than patients treated with fluid restriction.
- Conditions
- Hyponatremia, Dilutional Hyponatremia, Inappropriate ADH Syndrome
- Trial name
- SALACIA (NCT01227512)
- Testing
- tolvaptan, Fluid Restriction
- Where
- 56 sites in United States
- Volunteers
- 124 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Acute Respiratory Distress Syndrome, Acute Lung Injury
Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS)
The purpose of this study is to investigate the change of extravascular lung water (EVLW), cytokine and oxygenation parameters in patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) after alveolar…
- Trial name
- NCT01552070
- Testing
- Recruitment maneuver, without recruit maneuver
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy Adults
Safety of an Oral Probiotic in Healthy Adults
The purpose of this study is to evaluate the safety of an oral probiotic in healthy individuals.
- Trial name
- NCT04492631
- Testing
- Streptococcus salivarius DB-B5
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Dose Biosystems Inc.
Hyponatremia, Surgery
Fluid Tonicity and Hyponatraemia Post Surgery
Retrospective audit of adult patients who underwent major surgery in our institution, and biochemical outcomes including hyponatremia, in relation to the maintenance fluid tonicity administered peri-operatively.
- Conditions
- Hyponatremia, Surgery, Fluid and Electrolyte Imbalance
- Trial name
- NCT03840629
- Testing
- No study intervention.
- Volunteers
- 659 people
- Sponsor
- National University Hospital, Singapore
Diabetes, Diabetes Mellitus, Type 2
Investigation of Optimal Dosing Conditions for a Long Acting GLP-1 Analogue in Healthy Male Subjects
This trial is conducted in Europe. The aim of the trial is to evaluate the optimal dosing conditions for semaglutide (a long acting GLP-1 analogue) in healthy male subjects.
- Conditions
- Diabetes, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT01572753
- Testing
- semaglutide
- Where
- Germany
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Hypocalcemia, Thyroid
Is There Benefit From Early Postoperative PTH Monitoring?
This study is designed as a prospective non-randomized longitudinal single-center cohort study. It will enroll around 120 patients undergoing total thyroidectomy with data being collected from September 2019 up to December 2019.
- Conditions
- Hypocalcemia, Thyroid, Postoperative Complications, Parathyroid Dysfunction
- Trial name
- NCT04160637
- Testing
- Immediate postoperative PTH serum sampling and cut-off value identification
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University Hospital Sestre Milosrdnice
Type 2 Diabetes, Prediabetes
Effects of an Amino Acid and Chromium-picolinate Containing Drink on Glucose Metabolism
It has previously been shown in healthy overweight subjects, that table water including a defined amount of amino acids and chromium can decrease the postprandial glucose and insulin response.
- Trial name
- NCT02235194
- Testing
- Amino Acid and chromium-picolinate containing drink
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Stoffwechselzentrum Rhein - Pfalz
Treatment
Water for Reducing Pain in Negative Pressure Wound Therapy
Negative pressure wound therapy (NPWT) is a technique using vacuum dressing to promote wound healing in complicated wound. However for many patients, the application and removal of the NPWT is source of procedural pain.
- Trial name
- NCT02820272
- Testing
- NPWT with cold water, NPWT with normal saline room temp, NPWT without other intervention
- Volunteers
- 27 people
- Sponsor
- Chulalongkorn University
Extravascular Lung Water, Percutaneous Nephrolithotomy
Ultrasound Assessment of Extravascular Lung Water in Patients Undergoing Percutaneous Nephrolithotomy
Early detection of fluid accumulation in alveolar, interstitial and intracellular compartments of the lung due to intravascular absorption of irrigation fluid of PNL guided by lung ultrasound by detection of sonographic B lines.
- Trial name
- NCT06141746
- Testing
- Lung ultrasound
- Volunteers
- 100 people
- Sponsor
- Assiut University
Muscle Soreness
Neuromuscular Responses to Recovery Techniques
Cold water immersion (CWI) and percussive massage therapy (PMT) are commonly used re-covery techniques in team sports. In particular, despite its wide use, PMT has been scarcely investigated in the literature, especially…
- Trial name
- NCT06433856
- Testing
- Cold Water Immersion, Percussive Massage Therapy
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Bleeding Peptic Ulcer
Argon Plasma Coagulation vs Hemoclipping for Bleeding Peptic Ulcers
Endoscopic treatment is recommended for initial hemostasis in nonvariceal upper gastrointestinal bleeding. However, the additional hemostatic efficacy of argon plasma coagulation (APC) has not been widely investigated.
- Trial name
- NCT04366583
- Testing
- argon plasma coagulation, hemoclipping
- Where
- Taiwan
- Volunteers
- 166 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Diabetic Nephropathy
Aldosterone in Diabetic Nephropathy
The purpose of this study is to determine whether spironolactone are effective in the reduction of albuminuria and diastolic disfunction of subjects with diabetic nephropathy.
- Trial name
- ALDODN (NCT00870402)
- Testing
- Spironolactone
- Where
- Chile
- Volunteers
- 160 people
- Sponsor
- Universidad de los Andes, Chile
Hyperkalemia
Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia
Hyperkalemia is a common electrolyte disorder, especially among patients with chronic kidney disease, diabetes mellitus, or heart failure.
- Trial name
- InSaKa (NCT04012138)
- Testing
- Salbutamol, Insulin Aspart
- Where
- 16 sites in France
- Volunteers
- 419 people
- Sponsor
- Nantes University Hospital
Anesthesia, Thirst; Due to Deprivation of Water
Benefits of Drinking Clear Fluids Until Called to the Operating Room in Adult Surgical Patients
The purpose of this study is to show if - compared to standard practice - allowing adults undergoing surgical procedures under anaesthesia care to drink clear fluids up to a volume of 200 ml between 2 h prior to the operation and…
- Conditions
- Anesthesia, Thirst; Due to Deprivation of Water, Aspiration
- Trial name
- HYDRATE (NCT06253052)
- Testing
- Additional pre-OP-visit, Liberal fasting regime
- Where
- Germany
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Postpartum Hemorrhage, Pregnancy Related
Pharmacokinetic Equivalence of Calcium Gluconate and Calcium Chloride in Parturients
Calcium is a life saving medicine in the care of parturients. It has many important uses including treatment of hypocalcemia, treatment of magnesium toxicity, prevention of hypocalcemia during blood transfusion (of citrate…
- Conditions
- Postpartum Hemorrhage, Pregnancy Related, Hypocalcemia, Parturition Complication
- Trial name
- NCT05973747
- Testing
- Calcium Gluconate, Calcium chloride
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Stanford University
Water Turnover, Population Water Requirements
Study on Water Turnover of the Chinese Population Based on Deuterium Dilution Method
Water is essential for sustaining life and maintaining health. The human body relies on water to transport nutrients and waste products, lubricate joints, regulate body temperature, and preserve tissue structure.
- Conditions
- Water Turnover, Population Water Requirements, Deuterium Dilution
- Trial name
- NCT07028021
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Lower Urinary Tract Symptoms (LUTS)
RCT on Running Water Sound During Urodynamic
This study aims to see if listening to recorded running water sounds during a bladder function test (urodynamic study) helps patients feel calmer and makes it easier for them to empty their bladder during the test.
- Trial name
- NCT07451548
- Testing
- Auditory intervention with running water sound
- Where
- 2 sites in Hong Kong
- Volunteers
- 240 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Spastic Diplegia Cerebral Palsy
Comparative Effects of Under Water Exercise and Radial Extracorporeal Shockwave Therapy on Lower-Limb Spasticity, Gross Motor Function, and Quality of Life in Children With Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial
Children with spastic diplegic cerebral palsy often present with lower-limb spasticity, limited gross motor function, and reduced quality of life.
- Trial name
- spastic CP (NCT07878949)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Emad Eldin Mohamed
This Study is to Understand the Current Practice of Sodium Management in Acute Neurological Injury
Sodium Management in Acute Neurological Injury
This multicenter, observational, study will enroll severe neurologically injured patients both prospectively and retrospectively.
- Trial name
- SANI (NCT01558843)
- Where
- 17 sites in United States
- Volunteers
- 400 people
- Sponsor
- Washington University School of Medicine
Hygiene
The Impact of Improved WASH in Schools on Absence, Diarrhea and Helminth Infection in Lao PDR
The investigators will conduct a cluster-randomized trial to assess the impact of a school-based water, sanitation and hygiene program on health and educational outcomes of school children in Saravane Province, Laos.
- Trial name
- NCT02342860
- Testing
- WASH in Schools (WinS) programme
- Volunteers
- 8,873 people
- Sponsor
- Emory University
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