Clinical trials: Weak; Muscle
Trigger Point, Muscle Weakness
Effects of Deep Trigger Point Dry Needling on Strength Measurements of the Gluteus Medius Musculature
The purpose of this study will be to assess the effect that the application of deep trigger point dry needling to latent trigger points has on strength measurements.
- Trial name
- NCT03580200
- Testing
- Trigger Point Dry Needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emily Slaven, PT, PhD
Diabetic Foot Ulcer, Diabetic Wound
Peer Support for Patients With Diabetic Foot Ulcers
The objective of the study is to develop a peer support program that helps improve ulcer care in patients with a diabetic foot ulcer (DFU).Diabetes, peripheral arterial disease (PAD), foot ulceration, and subsequent amputation…
- Conditions
- Diabetic Foot Ulcer, Diabetic Wound, Diabetes Mellitus, Type 2, Diabetic Foot
- Trial name
- NCT06004219
- Testing
- Peer counseling group
- Where
- 3 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Statin-related Muscle Pain, Muscle Aches
7 Tesla MRI Study in Patients With Statin Related Muscle Complaints
Roughly 5-10% of statin-treated patients report muscle pain, aches, weakness, cramps, stiffness, or "heaviness" - typically occurring symmetrically in the legs.
- Conditions
- Statin-related Muscle Pain, Muscle Aches, Muscle Weakness, Muscle Cramp
- Trial name
- NCT04575090
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Muscle Weakness, Muscle; Fatigue, Heart
The Impact of Beef on Muscle Fatigue in Older Adults
The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults.
- Conditions
- Muscle Weakness, Muscle; Fatigue, Heart, Older Adults
- Trial name
- NCT05860088
- Testing
- Beef Diet, Vegetarian Diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Muscle Weakness
Investigation the Effect of Rectus Abdominis and Erector Spinae Muscle Fatigue on the Viscoelastic Properties of Thoracolumbal Fascia
The rectus abdominis, which enables the trunk to flex with its activation, and the erector spinae muscles, which provide trunk extension with its activation, are among the structures located in the core region and involved in the…
- Trial name
- NCT06432062
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Weakness of the Lower Limbs
VERARE : Effectiveness of Virtual Motor Actions for Improving Walking in Patients With Post-resuscitation Muscle Weakness
After a hospitalization in Intensive Care Unit (ICU), approximately 50% of patients usually have a ICU-Weakness, i.e. nerves and muscles injury secondary to immobilization and to treatments which had to be used.
- Trial name
- VERARE (NCT04441164)
- Testing
- Observation of Virtual Actions, Relaxation, Acceptability questionnaire
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Pelvic Floor Disorders, Postural; Defect
Hypopressive Effectiveness in Postural Control and Pelvic Floor.
Effects of an exercise program based on hypopressive exercises in the female population.
- Conditions
- Pelvic Floor Disorders, Postural; Defect, Muscle Weakness
- Trial name
- NCT04343599
- Testing
- Hypopressive exercises
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Sepsis, Acute Lung Injury(ALI)
Recovery of Physical Function After Critical Illness In Older Adults
The proposed study is a prospective, observational study assessing the recovery of muscle and physical function in patients surviving critical illness (n =150) at hospital discharge (baseline) and repeated serially.
- Trial name
- RETURN (NCT07225257)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Sarcopenia, Muscle Weakness
Foot Core Exercise Program on Balance Control and Walking in Aged Sarcopenia
In modern society with an increasing aging population, recent literature has defined sarcopenia as a significant reduced mass and function of skeletal muscle with physical limitations due to aging.
- Conditions
- Sarcopenia, Muscle Weakness, Walking, Difficulty, Balance Control
- Trial name
- NCT05750888
- Testing
- integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles, regular exercises for the elderly
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Sugammadex Reversal Time, Muscle Weakness
The Effect of Methylprednisolone on the Reversal Time of Rocuronium by Sugammadex in the Pediatric Patient Group
The aim of this study is to thoroughly investigate the interaction between methylprednisolone and sugammadex in the pediatric patient population.
- Trial name
- NCT06623370
- Testing
- methylprednisolone
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Pelvic Floor Muscle Weakness, Pelvic Floor Disorder
Does Hip Strength Impact Active Females Rate of Pelvic Floor Dysfunction? The Primary Goal of This Research is to Collect Data on Hip Strength for Active Females and Assess if There is a Relationship Between Hip Strength and Pelvic Floor Dysfunction (PFD).
The primary goal of this research is to collect data on hip strength for active females and assess if there is a relationship between hip strength and pelvic floor dysfunction (PFD).
- Conditions
- Pelvic Floor Muscle Weakness, Pelvic Floor Disorder, Pelvic Pain, Hip Strength
- Trial name
- NCT07119476
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- George Fox University
Flatfoot, Flexible, Pes Valgus
Physiotherapy Program Effect on Musculoskeletal Dysfunctions in Young Football Players
The goal of this clinical study is to test the proposed physiotherapy exercise program in young football players. The main question it aims to answer is: Does the proposed physiotherapy program work well in improving young…
- Conditions
- Flatfoot, Flexible, Pes Valgus, Pes Varus, Balance; Distorted
- Trial name
- NCT05798988
- Testing
- Neurophysiology-based exercise program
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Arthritis, Rheumatoid, Muscular Weakness
Neuromusuclar Adaptations in the Rheumatoid Arthritis Disease
Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes joint inflammation and progressive joint destruction. Rheumatoid cachexia is one of the structural manifestations of RA, and consists of a reduction in muscle…
- Trial name
- NCT03543488
- Testing
- Neuromuscular and functional capacity tests
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Hamstring Injury, Muscle Tone Increased
Cranial Laser Reflex Technique for Hamstring Function
Purpose: To conduct a pilot study of the effect of Cranial Laser Reflex Technique (CLRT) compared with sham laser on hamstring muscle flexibility, strength, and pain pressure threshold.
- Conditions
- Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
- Trial name
- CLRTHam (NCT03044106)
- Testing
- CLRT
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Low Back Pain, Muscle Weakness
NASM OPT for Gluteal Enhancement in Non-Athletic Women: An RCT
This RCT evaluates a 12-week NASM OPT program targeting gluteal muscle strength, hip aesthetics (shape, lift, circumference), and low back pain in 120 non-athletic women.
- Conditions
- Low Back Pain, Muscle Weakness, Body Image Disturbance
- Trial name
- GlutealEnhan (NCT06977958)
- Testing
- NASM OPT Group, General Exercise Group
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Age-related Muscle Decline
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding…
- Trial name
- CALM-AF-AI (NCT07443826)
- Testing
- AAV9-Follistatin gene therapy, VEGF Plasmid
- Where
- Honduras
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unlimited Biotechnology LLC
Muscle Weakness, Dynapenia
Mirror Neurons in Older Participants
A critical problem facing aging adults is muscle weakness. Whereas scientists have traditionally attributed the loss of muscle strength with aging to muscle atrophy, emerging evidence suggests that impairments in the…
- Conditions
- Muscle Weakness, Dynapenia, Sarcopenia
- Trial name
- MNOP (NCT03946709)
- Testing
- Action Observation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Pelvic Floor Muscle Weakness
Verbal Instruction for Contraction Pelvic Floor Muscles Among Males
The aim of this study is to compare the effectiveness of different verbal instruction on pelvic floor muscle contraction among males. Pelvic floor contraction will be measured via ultrasound.
- Trial name
- NCT03507660
- Testing
- verbal instruction
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Haifa