Clinical trials: Weakness
Respiratory Complication, Morbid Obesity
Does Residual Muscular Weakness Lead to an Increase in Respiratory Complications in Bariatric Patients?
The purpose of this study is to determine if residual weakness after weight loss surgery leads to an increased risk of respiratory complications in the postoperative period.
- Trial name
- NCT02037516
- Testing
- Accelomyography, Neostigmine, Qualitative Monitor
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Coastal Anesthesiology Consultants
Polymyositis, Dermatomyositis
Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis
This study determined the efficacy, safety, tolerability and the PK profile of BAF312, a novel immunomodulator, in polymyositis and dermatomyositis patients who were not responsive to traditional immunosuppressive and/or…
- Trial name
- NCT01148810
- Testing
- BAF312
- Where
- 6 sites in United States, Czechia and 3 more
- Volunteers
- 18 people
- Sponsor
- Novartis Pharmaceuticals
Copd, Inspiratory Muscle Weakness
Effects of Inspiratory Muscle Training on Shortness of Breath (Dyspnea) and Postural Control in Patients With COPD
Shortness of breath (dyspnea) is an important symptom during physical exertion in patients with chronic obstructive pulmonary disease (COPD) and is related to respiratory muscle weakness. Dyspnea is a multidimensional sensation.
- Trial name
- NCT03240640
- Testing
- Inspiratory Muscle Strength Training, Inspiratory Muscle Endurance Training
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- KU Leuven
Frailty Syndrome, Respiratory Muscle Weakness
Longitudinal Ultrasound Assessment of Diaphragmatic and Respiratory Muscle Function Following Respiratory Muscle Training in Frail Older Adults
This study aims to evaluate the effects of an 8-week inspiratory muscle training program on diaphragmatic and respiratory muscle function in frail older adults aged 80 years and above.
- Conditions
- Frailty Syndrome, Respiratory Muscle Weakness, Age-Related Frailty, Geriatric Health
- Trial name
- IMT-1 (NCT07258615)
- Testing
- Inspiratory Muscle Training
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Francisco de Vitoria
Postpartum, Muscle Fatigue
Muscle Function After Childbirth
This study will evaluate lower extremity and trunk neuromuscular control in 78 nulligravid and postpartum women. Participants will attend two experimental sessions, approximately 1 week apart, to assess neuromuscular function.
- Conditions
- Postpartum, Muscle Fatigue, Force Steadiness, Nulligravid
- Trial name
- NCT05073224
- Testing
- Active Straight Leg Raise Test, Active Straight Leg Raise Fatigue Task, Lower Extremity Strength Testing
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Carroll University
Postural Imbalance, Muscle Weakness
Effects of Corrective Exercises in Adolescent Fencers
The goal is to learn if a Functional Corrective Training (FCT) exercise program improves posture, core muscle endurance, jumping ability, and reaction time in adolescent fencers.
- Conditions
- Postural Imbalance, Muscle Weakness, Athletic Performance
- Trial name
- FMS exercise (NCT06927778)
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Muscular Weakness
Can Blood Flow Restriction Therapy Improve Strength for Shoulder External Rotators Better Than Exercise Alone
The purpose of this study is to evaluate the ability of blood flow restriction therapy to improve strength of shoulder muscles during the sidelying external rotation (ER) exercise versus a control group who only performs the…
- Trial name
- NCT03815760
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Fox University
Can Blood Flow Restriction Therapy Augments Strength Gains in the Rotator Cuff, Muscle Weakness
Can Blood Flow Restriction Therapy Improve Strength and Cross-Sectional Area for Shoulder External Rotators Better Than Exercise Alone?
This 8-week study will investigate whether the application of blood flow restriction (BFR) therapy augments rotator cuff strength in untrained individuals. This is a RCT with subjects randomized to a BFR or non-BFR group.
- Trial name
- NCT04596020
- Testing
- Blood Flow Restriction Group (exercise with blood flow restriction using a Delfi unit)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- George Fox University
Intensive Care (ICU) Myopathy, Intensive Care Unit Acquired Weakness
Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients
The aim of this study was to investigate the effect of neurophysiological facilitation techniques on respiratory and functional levels in intensive care patients.
- Trial name
- NCT05282576
- Testing
- NPF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Saglik Bilimleri Universitesi
Carnitine; Muscle, Functional Status
Impact on Functional Status in Older Adults Treated With L-Carnitine
This study evaluates the impact of the treatment with L-Carnitine on the function of adults over 65 years, in conjunction with regular exercise.
- Conditions
- Carnitine; Muscle, Functional Status, Old Age; Debility
- Trial name
- NCT03180424
- Testing
- L Carnitine, Supervised exercise, Exercise at home
- Where
- Uruguay
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clínicas Dr. Manuel Quintela
Copd, Muscle Weakness
Mechanical Muscle Proprieties in Patient with COPD
This study aims to determine if patients with Chronic Obstructive Pulmonary Disease (COPD) exhibit altered muscle properties (specifically changes in tone and stiffness) in both their respiratory muscles and skeletal muscles when…
- Conditions
- Copd, Muscle Weakness, Muscle Weakness Condition
- Trial name
- NCT06410950
- Testing
- MyotonPRO Assessment of Muscle Biomechanical Properties
- Where
- Romania
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Spitalul Clinic de Boli Infecțioase și Pneumoftiziologie Dr. Victor Babeș Timișoara
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Breast Cancer, Quality of Life
Pilates and Dance to Breast Cancer Patients Undergoing Treatment
Breast cancer is one of the most common types of cancer in Brazil, and its treatment, namely surgery, chemotherapy, radiotherapy or hormone therapy, has consequences and side effects that significantly affect the quality of life…
- Conditions
- Breast Cancer, Quality of Life, Lymphedema, Fatigue
- Trial name
- NCT03194997
- Testing
- Dance, Pilates
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Laboratório de Pesquisa em Lazer e Atividade Física
Movement Disorders
Physiology of Weakness in Movement Disorders
This study will compare electroencephalograph (EEG) recordings in healthy volunteers and in people with movement disorders to examine brain activity associated with the weakness.
- Trial name
- NCT00307346
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
COVID-19
Developing an Effective Intervention to Address Post-Corona-Virus-Disease-2019 Balance Disorders, Weakness and Muscle Fatigue in Individuals Aged 65+
The long-term consequences and sequelae of COVID-19 are still unclear; however, a vast number of elderly individuals have reported prolonged general weakness and muscular fatigue, leading to significant functional decline…
- Trial name
- NCT05934279
- Testing
- Resistance Training
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Józef Piłsudski University of Physical Education
Sarcopenic Obesity, Muscle Weakness
Mechanisms of Age-Related Muscle Loss
Two independent, but interrelated conditions that have a growing impact on healthy life expectancy and health care costs in developed nations are the age related loss of muscle mass (sarcopenia) and obesity.
- Conditions
- Sarcopenic Obesity, Muscle Weakness, Protein Metabolism Disorder, Physical Activity
- Trial name
- NCT03113279
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Muscle Weakness
Maximal Strength Training in Patients Undergoing Total Hip Arthroplasty
Conventional rehabilitation after total hip arthroplasty (THA) does not seem to restore muscular strength or walking speed. Three-5 years after surgery patients are still not fully rehabilitated.
- Trial name
- NCT02498093
- Testing
- Maximal strength training, conventional rehabilitation
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Breast Cancer
Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength…
- Trial name
- NCT02844504
- Testing
- Low Intensity Exercise Training 1, Low Intensity Exercise Training 2
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Resistance Exercise, Muscle Weakness
Effects of Elastic Band Resistance Exercise on Muscle Strength and Depression in Hospitalized Elderly.
With improved a five-day intensive, low-resistance elastic band exercise program to evaluate its effectiveness in improving total muscle mass, upper and lower extremity muscle strength, self-perceived fear of falling, and…
- Conditions
- Resistance Exercise, Muscle Weakness, Functional Decline
- Trial name
- NCT06205147
- Testing
- Elastic Band
- Where
- Taiwan
- Volunteers
- 62 people
- Sponsor
- National Taiwan University
Hyperkyphosis, Postural Kyphosis
Video-Based Game Therapy in Thoracic Hyperkyphosis
The scapula provides the base of the kinetic chain, which is stabilized by the surrounding muscles. Considering that activating the scapular musculature to stabilize the spine would restore the relationship between body segments…
- Conditions
- Hyperkyphosis, Postural Kyphosis, Exergaming, Muscle Weakness
- Trial name
- NCT05912478
- Testing
- Videogame-Based Therapy, Waiting list
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa
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