Clinical trials: Weight Changes, Body
Obesity
The Impact of the PACE Program Implementation on Health Services Utilization by Obese Arab Women
Scientific background: Obesity is a known risk factor for cardiovascular disease, metabolic syndrome, and diabetes. In Israel, the prevalence of obesity and diabetes among Arab females is 2 and 2.8 times higher than Jewish…
- Trial name
- AWESOME (NCT00827424)
- Testing
- Lifestyle counseling by applying a modified PACE protocol
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Clalit Health Services
Obesity
An Efficacy, Safety and Pharmacokinetics Study of Beloranib (ZGN-440 for Injectable Suspension) in Obese Subjects
The purpose of this study is to evaluate weight reduction, safety and pharmacokinetics for certain doses of beloranib (ZGN-440 for injectable suspension) administered as twice-weekly subcutaneous injections for 12 weeks.
- Trial name
- NCT01666691
- Testing
- Beloranib
- Where
- 3 sites in Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zafgen, Inc.
Weight Gain, Weight Loss
Gestational Weight Gain and Postpartum Weight Loss in Active Duty Women (Moms Fit 2 Fight)
The purpose of this study is to enroll approximately 450 subjects to see if a behavioral weight management program is successful in helping TRICARE beneficiaries who are pregnant or post-partum to manage their weight during and…
- Trial name
- NCT03057808
- Testing
- Gestational weight gain intervention, Postpartum weight loss intervention
- Where
- 2 sites in United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Obesity, Weight Loss
Optimizing Self-Monitoring Feedback for the Treatment of Obesity
Self-monitoring (of weight, intake, and activity) is a core component in evidence-based lifestyle interventions for obesity. Research has shown that interventionist feedback increases adherence to self-monitoring and improves…
- Trial name
- NCT06508580
- Testing
- Component 1: Calorie Goal Attainment, Component 2: Diet Quality, Component 3: Physical Activity Goal Attainment
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Florida
Weight Change
Comparison of Body Composition & Weight Change in Users of Progestin-only Contraception During the First Year of Use
The purpose of this study is to learn if women gain weight using progestin-only methods of contraception and if so, how much. The investigators will look at users of two progestin-only methods: the levonorgestrel-containing…
- Trial name
- DEXA (NCT01579773)
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Overweight
Predicting Adherence to a Heart-Healthy Diet in Lean and Obese Individuals
Background: Sticking to a diet plan can be difficult, but is important for many different health reasons. Some people seem to have a harder time following and sticking to a diet plan than others.
- Trial name
- NCT01862796
- Testing
- Underfeeding diet, Weight maintaining diet
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Military Operational Stress Reaction, Malnutrition (Calorie)
Physiological Response to Protein and Energy-enhanced Food Products During Winter Military Training
Soldiers commonly lose muscle mass during training and combat operations that produce large energy deficits (i.e., calories burned > calories consumed).
- Conditions
- Military Operational Stress Reaction, Malnutrition (Calorie), Weight Loss, Muscle Wasting
- Trial name
- NCT05210205
- Testing
- EAA, Energy Dense, Control
- Where
- Norway
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity, Weight Loss
Bariatric Embolization of Arteries for the Treatment of Nonalcoholic Steatohepatitis
Obesity is an epidemic in the US. With progression of obesity, Nonalcoholic steatohepatitis (NASH) has been a growing public health issue.
- Conditions
- Obesity, Weight Loss, Body Weight, Nonalcoholic Steatohepatitis
- Trial name
- NCT02933554
- Testing
- Embospheres Microspheres
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Keith Pereira, MD:
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Body Weight Changes, Body Weight
Differences in Fat Mass Estimation Formulas in Physically Active Adult Population and Relation With Skinfold Sums.
The objective of the present study was to analyze the differences between the formulas used to estimate fat mass and to establish the existing relationship with the skinfold sum in anthropometry.
- Trial name
- NCT04429581
- Testing
- Anthropometry
- Volunteers
- 2,458 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Weight Loss
Mother and Child Health Outcomes After Maternal Bariatric Surgery
Childhood obesity has been a growing problem with more than 30% of children between 6 and 19 years old being considered overweight or obese.
- Trial name
- NCT03297307
- Testing
- Presurgical Counseling
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Weight Loss
Journey to Better Health
This study is being conducted in 8 rural counties in Alabama and Mississippi (4 per state). Approximately 400 overweight or obese African American women living in the selected counties will participate in a 2-year weight loss…
- Trial name
- JTBH (NCT02938312)
- Testing
- Weight Loss Only, Weight Loss Plus
- Where
- United States
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
PreDiabetes, Diabetes Mellitus
Diabetes Risk Education and Communication Trial
A large body of research has demonstrated that intensive lifestyle interventions and metformin are effective treatments to prevent or delay diabetes among high-risk adults, yet neither treatment is routinely used in practice.
- Conditions
- PreDiabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Body Weight
- Trial name
- DiRECT (NCT03283657)
- Testing
- DiRECT, Usual care (UC)
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Obesity, Weight Loss
Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity.
- Trial name
- NCT06776081
- Testing
- Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Weight Reduction and Insulin Sensitivity
Fatty Acid Quality and Overweight (FO-study)
The purpose of this study is to study the health effects of fatty acid quality in healthy, overweight individuals.
- Trial name
- NCT01034436
- Testing
- fatty acid quality and overweight
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Overweight, Obesity
Trial of a Sugar-Sweetened Beverage Intervention in Overweight Mothers and Their Children Ages 3-5
The purpose of this study is to test the effect of a novel six-month behavioral program to reduce sugar-sweetened beverage consumption among preschoolers and their mothers.
- Trial name
- NCT02098902
- Testing
- Smart Moms Intervention
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Overweight, Obesity
Dietary Fibre and Chromium Picolinate Efficacy in Overweight and Obese Women
Obesity is one of the greatest causes of preventable morbidity and mortality worldwide with the main treatments requiring significant changes to lifestyle, particularly dieting and physical exercise.
- Trial name
- DFCP (NCT04250831)
- Testing
- agglomerated glucomannan, oligofructose and chromium mixture
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Behavioral, Activity
Weight Regain Study After Bariatric Surgery-A Pilot Project
There are three different phases to this study: 1. Screening phase to determine if you are eligible to participate in the study. 2.
- Conditions
- Behavioral, Activity, Weight Loss
- Trial name
- NCT02754453
- Testing
- Behavioral lifestyle intervention
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Heart Failure With Preserved Ejection Fraction (HFPEF)
The Effect of Adiposity on Muscle and Microvascular Function in HFpEF
This project is an observational study in patients with heart failure with preserved ejection fraction (HFpEF) who are candidates for treatment with weight loss medication to manage obesity or diabetes as part of their standard…
- Trial name
- NCT06930495
- Testing
- Weight loss SOC Treatment with second generation anti-diabetic medications
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Obesity
Elements Vital to Treat Obesity Study
The overall objective of this study is to evaluate the first rigorously optimized, remotely delivered treatment for obesity against the current gold standard treatment in a head-to-head randomized controlled trial.
- Trial name
- EVO (NCT04708769)
- Testing
- Smartphone App Participants (APP), Diabetes Prevention Program Participants (DPP)
- Where
- United States
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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