Clinical trials: Weight Changes, Body
Type 2 Diabetes, Overweight
Mechanisms of Weight Loss With SGLT2 Inhibition
The purpose of this study is to investigate the effect of canagliflozin, a medication approved by the FDA for the treatment of type 2 diabetes, on body weight and metabolism in people with type 2 diabetes who are overweight or…
- Conditions
- Type 2 Diabetes, Overweight, Obesity
- Trial name
- NCT02360774
- Testing
- Canagliflozin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Beth Israel Deaconess Medical Center
Obesity and Obesity-related Medical Conditions
Weight Changes After Incretin-mimetics
The goal of this study is to identify people at risk of weight regain after stopping an injectable weight loss drug. The main question the investigators aim to answer is: Can weight regain be predicted by measuring circulating…
- Trial name
- NCT06795360
- Testing
- discontinuation of weight loss medication
- Volunteers
- 52 people
- Sponsor
- Medical College of Wisconsin
Type 2 Diabetes, Overweight and Obese Adults
Plant-Based Online Weight Loss Through Education and Resources Program and Study
This is an interventional study that will evaluate the feasibility, implementation, and efficacy of an online, 12-week, plant-based, nutrition education program in a community setting.
- Trial name
- POWER (NCT07095543)
- Testing
- Low-fat, vegan diet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Physicians Committee for Responsible Medicine
Poly Cystic Ovary Syndrome, Overweight , Obesity
Physical Activity and Cardiometabolic Health in Women With or Without Polycystic Ovary Syndrome (SCOPAP)
The primary objective of this study is to investigate the effects of a multidisciplinary intervention, including a targeted adapted physical activity program, on lipid oxidation during a walking exercise in women with overweight…
- Trial name
- SCOPAP (NCT07659392)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Clermont-Ferrand
Frailty Syndrome
Ghrelin Plus Strength Training in Frail Elderly Study
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty.
- Trial name
- NCT01898611
- Testing
- Ghrelin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Pennsylvania
Obesity, Type 2 Diabetes
Gene x Behavior Interaction in the Look AHEAD Study
The interplay of genetic and behavioral factors is critical to understanding obesity. Behavioral weight loss intervention has emerged as a key strategy in combating obesity.
- Trial name
- NCT01270763
- Testing
- Intensive lifestyle intervention, Diabetes support and education
- Where
- United States
- Volunteers
- 4,108 people
- Sponsor
- The Miriam Hospital
Obesity
Integrating Small Changes and Positive Psychology to Improve Treatment Readiness: A Weight Loss Trial
The study is designed to compare short- and long-term changes in body weight (kg) and subjective well-being in adult females with obesity who have been randomized to receive one of two 6-month treatment conditions: INSPIRE or…
- Trial name
- INSPIRE (NCT04487158)
- Testing
- Small Changes, INSPIRE
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Obesity
Weight Gain in First-year University Students
The transition to university from secondary school comes with many changes to living arrangements, dietary and alcohol intake, physical activity, and stress.
- Trial name
- NCT05856734
- Testing
- Weight and body composition change, Change in dietary intake, Change in physical activity
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Esophageal Cancer, Gastric Cancer
Octreotide Treatment to Improve Nutritional Recovery After Surgery for Patients with Esophageal or Gastric Cancer
The aim of the study is to clarify whether octreotide therapy can reduce undesired postoperative weight loss, increase health-related quality of life and improve the appetite after surgery for esophageal or gastric cancer.
- Trial name
- OTIS (NCT04871204)
- Testing
- Octreotide Injection
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Fredrik Klevebro
Obesity, Diabetes Mellitus, Type 2
Behavior Intervention for Weight Loss for Type 2 Diabetes Mellitus Adults With Obesity Problem (BMI of ≥23kg/m2)
This quasi-experimental study aims to determine the effectiveness of a health intervention (Chance2Act) on behaviour change to act for weight loss among overweight/obese type 2 diabetes adults.
- Conditions
- Obesity, Diabetes Mellitus, Type 2, Behavior
- Trial name
- BMI (NCT05736536)
- Testing
- Chance2Act
- Where
- 2 sites in Malaysia
- Volunteers
- 104 people
- Sponsor
- Universiti Teknologi Mara
Breast Cancer, Body Weight Change
The Study is Observational and Retrospective: Lifestyle, BMI and Activity Physical.
The goal of this observational-retrospective study is to learn about the long-term effects of a lifestyle intervention inclusive of dietary counselling and physical activity advice, on body weight in female breast cancer…
- Trial name
- Lifestyle (NCT06866093)
- Testing
- Lifestyle
- Where
- Italy
- Volunteers
- 112 people
- Sponsor
- National Cancer Institute, Naples
Anemia, Iron-Deficiency, Weight Loss
Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty
The purpose of this study is to determine whether intravenous or oral iron are effective in the treatment of postoperative anemia and iron deficiency in patients submitted in postbariatric abdominoplasty.
- Trial name
- ISAPA (NCT01857011)
- Testing
- Intravenous Iron sucrose, Oral Iron
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo
Time Restricted Eating, Obesity
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically…
- Conditions
- Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
- Trial name
- NCT05114798
- Testing
- Time restricted eating, Calorie Restriction
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Metabolic Syndrome X, Cachexia
The Roles of Cytokines in the Mechanism of Insulin Resistance and Energy Balance
Insulin resistance and disturbances in energy homeostasis are associated with body weight changes, such as diabetes, hypertension, hyperlipidemia, obesity, cancer cachexia, aging, and acute or chronic infectious diseases.
- Conditions
- Metabolic Syndrome X, Cachexia, Insulin Resistance
- Trial name
- NCT00172614
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Obesity, Obstructive Sleep Apnea
Changes in Body Fat and Morphologic Characteristics Associated With OSA Resolution After Bariatric Surgery
Prospective study with inclusion of bariatric surgery candidates with diagnosed Obstructive Sleep Apnea and requiring treatment with Continuous Positive Air Pressure, aiming to evaluate at 2-6-12 months after bariatric surgery…
- Trial name
- NCT05315752
- Testing
- Bariatric surgery
- Where
- 2 sites in Belgium
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Weight Loss
The Effects of Capsinoids on Brown Adipose Tissue Activation in Obesity
This research study is being done to determine whether taking a dietary supplement called capsinoids, derived from sweet peppers, can activate brown fat that is already present or even generate new brown fat in individuals with…
- Trial name
- BATCAP (NCT03110809)
- Testing
- Capsinoid
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Post-bariatric Surgery
The Effect of Supervised Exercise on Physical Fitness and Energy Expenditure in Post Bariatric Surgery Patients
It is hypothesized that the patients in the EXDA group will be able to complete a structured exercise program at a level sufficient to accumulate at least 2000 kcal per week, and that the structured endurance activity will…
- Trial name
- NCT00793832
- Testing
- supervised exercise, Diet advice
- Volunteers
- 33 people
- Sponsor
- University of Texas Southwestern Medical Center
Overweight and Obesity, Pre-Diabetes
Stepping Into Lifestyle Changes
The purpose of this study is to promote healthy weight loss among African American women, age 30 or older, who are pre-diabetic and/or have high blood pressure and who live, work, or worship in select rural communities throughout…
- Conditions
- Overweight and Obesity, Pre-Diabetes, High Blood Pressure
- Trial name
- SILC (NCT05625321)
- Testing
- Educational Group Weight Loss Classes, Home Gardening Intervention
- Where
- 2 sites in United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
The Leisure-time Activity and Nutrition Program
The purpose of this investigation is to conduct an 8-week pilot study to examine the effects of two different leisure-time activity prescriptions on dietary intake, leisure-time activities, and weight loss in 30 adults receiving…
- Trial name
- LEAN (NCT01142206)
- Testing
- Dietary, Physical Activity, TV Watching + Physical Activity
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity and Obesity-related Medical Conditions, Weight Loss
Five PLus Year EffIcacy of Endoscopic Sleeve Gastroplasty (ESG) for Sustained WeigHT Loss
The objective of this study is to assess the long term weight loss and weight loss journey of patients who received an Endoscopic Sleeve Gastroplasty (ESG) 5 or more years prior to enrollment.
- Trial name
- LIGHT (NCT06894498)
- Testing
- No Intervention: Observational Cohort
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Boston Scientific Corporation
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