Clinical trials: Weight Changes, Body
Type 1 Diabetes
Efficacy of Pramlintide on Prevention of Weight Gain Early Onset of Type 1 Diabetes
In this pilot study we are evaluating the efficacy of pramlintide on preventing weight gain among early onset type 1 diabetes. We are also evaluating the safety and the effects of treatment with pramlintide on early diagnosed…
- Trial name
- NCT00505882
- Testing
- Pramlintide, Glargine, Lispro
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Cachexia, Cancer
Effectiveness of Nutritional Counselling and "Improved Atta" Supplementation in Cachexic Adult Indian Cancer Patients
Investigators are evaluating the nutritional role of IAtta supplementation along with nutritional counselling in delaying the progression of cachexia to refractory cachexia in adult cancer Indian patients.
- Trial name
- NCT02561143
- Testing
- Improved Atta, Wheat flour, Physical activity counseling
- Where
- 2 sites in India, United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Westminster
Overweight and Obesity, Dyslipidemias
Enriched Honey With Soluble Fiber and Polyphenols on Satiety and Dyslipidemia
The aim of this trial is to evaluate the possible benefits on saciety and dyslipidemia in subjects with overweight/obesity (BMI ≥25 y <40 kg / m2) and dyslipemia after consumption of a modifed honey with soluble fiber and…
- Trial name
- SACIMIEL (NCT04153617)
- Testing
- Control honey, Modified honey with soluble fiber and polyphenols
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Polycystic Ovary Syndrome, Weight Gain
Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity
this is open labelled randomize control trial among women with PCOS. PCOS, an endocrine condition, affects 5%-15% of premenopausal women.
- Conditions
- Polycystic Ovary Syndrome, Weight Gain, HbA1c
- Trial name
- NCT06140108
- Testing
- Empagliflozin 10 MG, MetFORMIN 500 Mg Oral Tablet
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- SINA Health Education and Welfare Trust
Obesity, Overweight
Physiological Factors That Influence Maintenance of Lifestyle Changes and Weight Loss - a Longitudinal Study
In Denmark and the western world, there is an increasing prevalence of obesity probably due to a combination of inadequate daily physical activity and a high energy intake.
- Trial name
- NCT01997060
- Testing
- Intensive Lifestyle Intervention
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Change in Total Body Fat Mass Percentage Loss Versus Body Weight
Evaluation of Sinetrol® Xpur in Fat Mass Reduction on Overweight and Obese Subjects
This study aims to evaluate effects of a 16-week supplementation with a polyphenol rich extract, Sinetrol® Xpur, on fat mass accumulation and body weight management improvement.Subjects were overweight or obese and received…
- Trial name
- NCT04149158
- Testing
- Sinetrol® Xpur
- Where
- Spain
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Fytexia
Osteoarthritis, Knee, Obesity
Long-term Intervention With Weight Loss in Patients With Concomitant Obesity and Knee Osteoarthritis. The LIGHT Study
Obesity and osteoarthritis (OA) co-exist in an increasing part of the population. The two diseases intertwine in several ways. The evolution in the population shows a tendency towards deterioration of both by increasing general…
- Trial name
- LIGH T (NCT00938808)
- Testing
- day formula diet
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Henning Bliddal
Body Weight, Body Weight Changes
Online Family Dyadic Skills Training for Black Adults in Behavioral Weight Loss Program
The purpose of this research study is to test the feasibility and acceptability of an interactive counselor -led online family skills training as part of a behavioral weight loss program for Black Adults.
- Conditions
- Body Weight, Body Weight Changes, Obesity, Overweight and Obesity
- Trial name
- TEAM+ (NCT05981508)
- Testing
- Together, Eating and Activity, Matter Plus (TEAM+) Online, Together, Eating and Activity, Matter Plus (TEAM+) In-Person
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity
A Study to Evaluate the Efficacy and Safety of PF-06882961 in Adults With Obesity
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called PF-06882961) for the potential treatment of obesity.
- Trial name
- NCT04707313
- Testing
- PF-06882961 (Cohorts 1 and 2), PF-06882961 (Cohort 3)
- Where
- 41 sites in United States, Canada and 2 more
- Volunteers
- 628 people
- Sponsor
- Pfizer
Obesity
Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults
This trial examines the effects of grapefruit or grapefruit juice on anthropometry, dietary intakes, appetite, and metabolic profile in overweight and obese young and middle-aged adults.
- Trial name
- GJW (NCT00581074)
- Testing
- diet (grapefruit or grapefruit juice)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Weight Loss
Get Social: Randomized Trial of a Social Network Delivered Lifestyle Intervention
The present study is a non-inferiority trial comparing the efficacy of a lifestyle intervention delivered entirely via an online social network to a traditional lifestyle intervention delivered via group meetings.
- Trial name
- NCT02646618
- Testing
- Get Social, Traditional, Smartphone
- Where
- United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Critical Illness, Fluid Overload
Fluid Balance and Body Weight Changes in Critically Ill Adult Patients
Positive fluid status has been consistently associated with worse prognosis in critically ill adult patients.However, observational studies showed poor agreement between fluid balance and body weight changes.
- Trial name
- NCT04434079
- Testing
- Regular critical care
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dietary Modification, Bread
Testing the Effect of Whole-wheat Sourdough Bread Compared to White Bread on Healthy Individuals
Bread is the most common grain product in the world, with consumption surpassing 3 billion individuals per year. Sourdough whole-grain bread is considered a healthy alternative to white, refined-wheat bread.
- Conditions
- Dietary Modification, Bread, Gastrointestinal Microbiome, Hematologic Tests
- Trial name
- NCT02936362
- Testing
- Consumption of sourdough bread, Consumption of white bread
- Where
- 2 sites in Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Weight Loss
The Outcome of Abdominoplasty After Massive Weight Loss
The primary aim of this study is to compare early surgical complications after abdominoplasty performed by plastic and general surgeons.
- Trial name
- NCT02679391
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Morbid Obesity, Type2diabetes
Comorbidities Resolution After MGB Surgery and Change in Body Composition
This observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients.
- Conditions
- Morbid Obesity, Type2diabetes, Sleep Apnea, Hypothyroidism
- Trial name
- MOGAMBO (NCT06015620)
- Testing
- Mini gastric bypass surgery
- Where
- India
- Volunteers
- 35 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Overweight, Obesity
SCALE: Small Changes and Lasting Effects
The goal of this study is to translate basic behavioral and social science discoveries into effective behavioral interventions that reduce obesity and obesity related morbidity in Black and Latino communities.
- Trial name
- SCALE (NCT01198990)
- Testing
- Group 1, Group 2
- Where
- 6 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Lipolysis, Overweight and Obesity
Efficacy of a Lipolytic Cream in an Overweight and Obesity Treatment
The coadyouvant efficacy of a combination of cosmetics ingredients in the form of a lipolytic cream with hypocaloric diet and physical activity were assessed and compared with with hypocaloric diet and physical activity for…
- Conditions
- Lipolysis, Overweight and Obesity, Diet Modification, Physical Activity
- Trial name
- NCT03721185
- Testing
- Dr.K. Treatment
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- BiomediKcal
Obesity, Bariatrics
Comparing the Benefits and Harms of Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study
The main goal of this research project is to conduct a comparative effectiveness research study involving existing data in the PCORnet Common Data Model to provide accurate estimates of the 1-, 3-, and 5-year benefits and risks…
- Conditions
- Obesity, Bariatrics, Body Weight, Diabetes Mellitus
- Trial name
- PBS (NCT02741674)
- Testing
- Roux-en-y gastric bypass (RYGB) - historical, Adjustable gastric banding (AGB) - historical, Sleeve gastrectomy (SG) - historical
- Volunteers
- 65,093 people
- Sponsor
- Kaiser Permanente
Weight Loss, Weight Gain Prevention
Improving Appetite Regulation in Patients With Obesity
Over 70% of U.S. adults have overweight or obesity. Currently, the most efficacious behavioral intervention for obesity is standard behavioral treatment (SBT), often composed of group sessions, calorie goals, and physical…
- Conditions
- Weight Loss, Weight Gain Prevention, Obesity
- Trial name
- NCT05200520
- Testing
- Appetite Self-Regulation Intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bariatric Surgery, Sleeve Gastrectomy
15-years Outcomes of Sleeve Gastrectomy on Weight Loss
Evaluate the beneficial and harmful effects of sleeve gastrectomy at 15 years in a pioneering center for this surgical technique in France
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Weight Loss
- Trial name
- SLEEVE15 (NCT07883018)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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