Clinical trials: Weight Changes, Body
Diabetes Mellitus, Type 2, Obesity
L-arginine and Asymmetric Dimethylarginine (ADMA) and Lifestyle Protocols
Low serum L-arginine (Arg) and high asymmetric dimethylarginine (ADMA) can predict microvascular complications in type 2 diabetes (T2DM).
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Arginine, Asymmetric Dimethylarginine
- Trial name
- NCT04406402
- Testing
- Acute dietary protocols and lifestyle modification
- Where
- Israel
- Volunteers
- 243 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Weight Loss
Video Conferencing and In-person Health Coaching on Weight Loss, Physical Activity, and Metabolic Control
The purpose of this study was to determine how 12 weeks of health coaching with individualized feedback and education in combination with mobile health devices (a digital wireless body weight scale and wireless activity tracker)…
- Conditions
- Obesity, Weight Loss, Telemedicine
- Trial name
- NCT03278951
- Testing
- Video Conferencing Group, In Person Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Binge Eating Disorder, Overweight and Obesity
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
The purpose of this research is to conduct a randomized controlled trial (RCT) assessing the impact of CBT on neural responses to binge eating stimuli.
- Trial name
- NCT03604172
- Testing
- Cognitive behavioral therapy, Waitlist
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity Type 2 Diabetes Mellitus, Obesity & Overweight
Eating Behaviour Before, During, and After Obesity Medication
This study will examine how eating behaviour changes during the first 18 months of treatment with obesity medications in patients attending the St Vincent's Healthcare Group obesity service.
- Trial name
- NCT07636395
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University College Dublin
Weight Loss
Opt-IN: Optimization of Remotely Delivered Intensive Lifestyle Treatment for Obesity
The overall objective of the proposed research is to use an innovative methodological framework, the Multiphase Optimization Strategy (MOST), to design, for the first time, an optimized, scalable version of a technology-supported…
- Trial name
- Opt-IN (NCT01814072)
- Testing
- 12 Telephone Coaching Sessions, 24 Telephone Coaching Sessions, Report to Primary Care Physician
- Where
- United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Overweight and Obesity
Dairy Foods and Weight Loss
Obesity is a national epidemic with multiple causes and complex solutions. Research in both animals and humans has suggested that the inclusion of dairy foods into a moderate calorie restricted diet can increase weight loss and…
- Trial name
- NCT00858312
- Testing
- high dairy diet, Low Dairy
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Old Age; Cachexia, Dietary Habits
The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
The food intake is often compromised in the elderly, and during hospitalization, dietary restrictions may be imposed, making them more susceptible to the risk of malnutrition and sarcopenia.
- Conditions
- Old Age; Cachexia, Dietary Habits, Sarcopenia, Protein Malnutrition
- Trial name
- NCT05502445
- Testing
- educational intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Israelita Albert Einstein
Obesity, Osteoarthritis
Reducing Obesity and Cartilage Compression in Knees
OA is a degenerative joint disease that involves the degradation of articular cartilage and underlying subchondral bone. Obesity is identified as a critical and potentially modifiable risk factor for the development and…
- Conditions
- Obesity, Osteoarthritis, Knee Osteoarthritis
- Trial name
- ROCCK (NCT04730557)
- Testing
- Weight Loss
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Duke University
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
This clinical trial aims to evaluate the effectiveness of tirzepatide in achieving a 5% or more body weight reduction in patients undergoing adjuvant treatment for hormone receptor-positive, HER2-negative (HR+/Her2-) breast…
- Trial name
- FITWISE (NCT06518837)
- Testing
- Tirzepatide
- Where
- 7 sites in United States
- Volunteers
- 40 people
- Sponsor
- Rutgers, The State University of New Jersey
Gestational Diabetes, Pregnancy Complications
Gestational Diabetes Monitoring and Management
The primary goal is to predict the clinical outcomes of mother and baby using blood glucose and other routinely collected clinical data in pregnancy to predict adverse outcomes at birth in women with GDM.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT06963528
- Where
- United Kingdom
- Volunteers
- 1,800 people
- Sponsor
- University of Oxford
Overweight and Obesity
Adapting Mindful Eating Program for French Overweight/Obese Population
The aim of this project is to validate a new mindful eating programme adapted to the overweight or obese French population. Recognising the importance of diet in the management of chronic diseases, particularly obesity, and the…
- Trial name
- MIND-EAT (NCT06157411)
- Testing
- Mindful Eating Intervention (AC group), Conventional Dietetic Intervention (DC group)
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Montpellier
Weight Loss, Obesity
The Effect of Telephone and Video Counseling on Weight Loss and Quality of Life
Individuals with obesity are at higher risk for severe disease, hospitalizations, and death from the SARS-CoV-2 virus. Social distancing guidelines intended to prevent viral spread during the COVID-19 pandemic resulted in major…
- Trial name
- NCT05276544
- Testing
- Dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ankara University
Bariatric Surgery Candidate, Obesity, Morbid
Adolescents Bariatric Surgery Cohort Survey
Obesity affects 3%-4% of the pediatric population and leads to cardiac mortality during adult life. Bariatric surgery is the best treatment for weight loss and preventing obesity associated comorbidities in adults, but its…
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Obesity, Adolescent
- Trial name
- BariAdo (NCT04766801)
- Testing
- Laparoscopic adjustable gastric banding
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Angers
Cardiometabolic Syndrome, Obesity and Cardiovascular Risk
Lifestyle Changes, Mushroom Supplementation, and Bupropion to Reduce Adiposity and Cardiometabolic Risk
The increasing prevalence of obesity, its serious health consequences, and the substantial economic burden on healthcare systems underscore a pressing need for effective, long-term prevention strategies that can be implemented in…
- Conditions
- Cardiometabolic Syndrome, Obesity and Cardiovascular Risk, Overweight , Obesity
- Trial name
- NCT07806279
- Testing
- Bupropion 150 mg, Lyophilized powder from edible mushrooms, Lifestyle Management
- Where
- 3 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Uppsala University
Weight Loss, Ovarian Carcinoma
Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss
the aim is to study skeletal muscle metabolism alterations métaboliques associated with weight loss in women with ovarian and/or endometrial cancer according to BMI.
- Conditions
- Weight Loss, Ovarian Carcinoma, Endometrial Carcinoma
- Trial name
- METERMUS-IMC (NCT03027479)
- Testing
- Samples
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Tours
Ulcerative Colitis (Disorder), Crohn Disease
Partial Enteral Nutrition to Prevent Weight Loss and Sarcopenia in IBD Patients at Nutritional Risk - SIMBA
This is a multicenter, open-label, randomized two-arm interventional nutritional study evaluating the effects of partial enteral nutrition (LH VIOLA) in patients with Inflammatory Bowel Disease (IBD) at risk of malnutrition.
- Conditions
- Ulcerative Colitis (Disorder), Crohn Disease, Malnutrition or Risk of Malnutrition, IBD
- Trial name
- SIMBA (NCT07433946)
- Testing
- LH VIOLA Supplementation
- Where
- 4 sites in Italy
- Volunteers
- 146 people
- Sponsor
- Lionhealth Srl Società Benefit
Blood Glucose, High, Body Weight Changes
Composite Flour and Its Antdiabetic Potential
A low glycemic multigrain flour for chapattis will be made from grains and cereals that are easily available in Pakistan. The nutritional profile and composition of test flour will be checked through proximate analysis method…
- Conditions
- Blood Glucose, High, Body Weight Changes, Hyperlipidemias, Body Composition
- Trial name
- NCT05163587
- Testing
- low GI composite flour
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Type 2 Diabetes, Obesity
Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in Diabetes
The purpose of this study is to see how hormones that control blood sugar change in response to two different weight loss surgeries (gastric bypass and gastric banding).
- Conditions
- Type 2 Diabetes, Obesity, Bariatric Surgery
- Trial name
- NCT01153438
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Pennsylvania
Weight Gain, Human Milk
Growth and Weight Gain in ELBW Infants Fed an Exclusively Human Milk Based Diet With Prolacta®
Preterm infants are susceptible to postnatal growth restriction. Breast milk is the recommended source of nutrition for preterm infants.
- Conditions
- Weight Gain, Human Milk, Preterm Infants, Extremely Low Birth Weight
- Trial name
- NCT03886844
- Testing
- Human milk fortifier based on human milk (Prolacta)
- Where
- 2 sites in Austria
- Volunteers
- 196 people
- Sponsor
- Medical University of Vienna
Bariatric Surgery, Sleeve Gastrectomy
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study A
The purpose of the study is to evaluate how dietary habits in the post-surgical year impact outcomes of bariatric surgery.
- Conditions
- Bariatric Surgery, Sleeve Gastrectomy, Obesity
- Trial name
- NCT03470558
- Testing
- Dietary habits
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- Brigham and Women's Hospital
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