Clinical trials: Weight Loss Trial
Obesity, Overweight
Comparing Effect of Short Sleep Duration on Weight Loss of Overweight and Obese Women Attending a Weight Loss Program
The purpose of the present study is to evaluate the effect of sleep duration on weight loss of obese and overweight adult when they are in a weight loss plan (NovinDiet Protocol).
- Trial name
- NCT03120260
- Testing
- Diet
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Cardiometabolic Risk, Weight Loss
Effects of Caloric Restriction and Exercise on Body Weight, Immune Function, and Intestinal Flora
The purpose of this study is to estimate the effects of caloric restriction and exercise on body weight, cardiovascular metabolic markers, immune function, and intestinal flora among college students, as well as the underlying…
- Conditions
- Cardiometabolic Risk, Weight Loss, Immune System, Intestinal Microbiome
- Trial name
- NCT04275440
- Testing
- Exercise, Caloric restriction
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Obesity, Overweight
Effects of Late Dinner Against Early Dinner on Weight Loss Healthy Obese Women
The aim of the present study is to test whether late eating dinner could affect the amount of weight loss in healthy obese women in a weight-loss program.
- Trial name
- NCT03129841
- Testing
- Early dinner+Diet, Late dinner+Diet
- Where
- Iran
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Novindiet Clinic
Obesity
An Efficacy, Safety and Pharmacokinetics Study of Beloranib (ZGN-440 for Injectable Suspension) in Obese Subjects
The purpose of this study is to evaluate weight reduction, safety and pharmacokinetics for certain doses of beloranib (ZGN-440 for injectable suspension) administered as twice-weekly subcutaneous injections for 12 weeks.
- Trial name
- NCT01666691
- Testing
- Beloranib
- Where
- 3 sites in Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zafgen, Inc.
Obesity
Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
The purpose of this study is to compare two approaches to a diet and exercise-based weight loss program.
- Trial name
- SHINE (NCT00960414)
- Testing
- SHINE
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Overweight, Obesity
Hockey Fans in Training (Hockey FIT): Improving Men's Health Through the Power of Sport
Hockey Fans in Training (Hockey FIT) is a 12-month (3-month active phase and 9-month minimally-supported phase) weight loss and healthy lifestyle program for middle-aged, male hockey fans with overweight or obesity, delivered by…
- Trial name
- NCT03636282
- Testing
- Hockey FIT Program (Immediate Delivery)
- Where
- 40 sites in United States, Canada
- Volunteers
- 997 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Obesity, Binge Eating
Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons
This is a research study designed to examine the effectiveness of an obesity medication (orlistat) given in addition to behavioral weight loss therapy. Participants will be obese monolingual (Spanish-speaking only) men and women.
- Trial name
- NCT00516919
- Testing
- Xenical + behavioral intervention
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yale University
Obesity, Severe Obesity
Energy Expenditure From ECAL Indirect Calorimeter in a Multicomponent Weight Management Service
Whether greater weight loss is as a result of a smaller reduction in energy expenditure with caloric restriction is not known. Resting energy expenditure and 24-hour energy expenditure vary substantially between individuals.
- Conditions
- Obesity, Severe Obesity, Sleep Apnoea
- Trial name
- ECAL (NCT03638895)
- Testing
- ECAL Indirect Calorimeter, Diet, exercise & behaviour modification therapy
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Weight Loss
Cost-Effectiveness of Weight Loss Prevention in Nursing Homes: A Controlled Trial
Low oral food and fluid intake and unintentional weight loss are common problems among long-stay nursing home (NH) residents and are associated with adverse, costly clinical outcomes.
- Trial name
- NCT02567513
- Testing
- Supplement Intervention, Snack Intervention
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Obesity, Weight Loss
Feasibility Trial of a Problem-Solving Weight Loss Mobile Application
The purpose of this research was to develop and test the feasibility of Habit, a weight loss mobile application that was designed to coach patients through their weight loss challenges.
- Trial name
- NCT02192905
- Testing
- Diabetes Prevention Program Lifestyle Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Overweight and Obesity, Overweight Adolescents
Efficacy of Oral Vitamin D Supplementation in Adolescents and Young Adults.
This study assesses whether oral supplementation with vitamin D contributes to the reduction of body mass index and lipid profile in adolescents and young adults.
- Conditions
- Overweight and Obesity, Overweight Adolescents, Vitamin D Deficiency
- Trial name
- SIMBAIII (NCT04377386)
- Testing
- 1000 IU D vitamin, 200 IU D vitamin
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Fundación Cardiovascular de Colombia
Blood Pressure, Sleep Health
The Sleep2BWell Trial
Improving multiple domains of cardiometabolic health (CMH) through contextual behavioral interventions has the potential to substantially reduce persistent chronic disease disparities.
- Conditions
- Blood Pressure, Sleep Health, Diet, Healthy, Physical Activity
- Trial name
- NCT06565104
- Testing
- Multidimensional Sleep Health Sessions, Healthy Diet Sessions, Physical Activity Sessions
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Columbia University
Binge Eating Disorder, Binge Eating
Effectiveness of a 10-week Multicomponent Intervention Combined With Parent Education on Binge Eating Behavior in Children and Adolescents
The main purpose is to investigate the effectiveness of a 10-week multicomponent camp intervention to reduce BE behavior in children and adolescents and explore in a randomized controlled setting if a parent-based…
- Conditions
- Binge Eating Disorder, Binge Eating, Loss of Control Eating, Overweight , Obesity
- Trial name
- STOB (NCT07301541)
- Testing
- A 10-week multicomponent camp intervention for children, A BED intervention for parents
- Where
- 2 sites in Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Weight Loss, Weight, Body
Pilot Trial of a Telephone Weight Loss, Nutrition, Exercise Study
Many behavioral weight loss interventions have been developed, but still have significant limitations in terms of achieving clinically significant, sustained weight loss.
- Trial name
- WeLNES (NCT03738540)
- Testing
- TALK study group, TALK control group
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Obesity
Intermittent Eating on Sustaining Weight-loss in Obesity
Weight regain after weight loss is a major problem in the treatment of obesity. Two novel types of intermittent fasting recently have received more attention: the 5:2 diet and time-restricted eating (TRE).
- Trial name
- INTEREST (NCT05453617)
- Testing
- Time-restricted eating, The 5:2 diet
- Where
- China
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Obesity
Research Study of Nutritional Methods to Reduce Body Fat Percentages in Overweight and Obese Populations
The purpose of this study is to compare the use of personalized low-fat meal plans vs. non-personalized low-fat meal plans and the results in body fat reduction in overweight and obese subjects 25 to 45 years of age.
- Trial name
- NCT00487344
- Testing
- Non-Personalized Meal Planning, Personalized Meal Planning and Dietetic Consultation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Central FITT, Inc
Cardiovascular Diseases, Diabetes
Fit After Baby: Increasing Postpartum Weight Loss in Women at Increased Risk for Cardiometabolic Disease
This study plans to learn more about how to increase postpartum weight loss and how to decrease risk factors for postpartum women at increased risk for diabetes and heart disease.
- Conditions
- Cardiovascular Diseases, Diabetes, Gestational Diabetes, Preeclampsia
- Trial name
- FAB (NCT03215173)
- Testing
- Fit After Baby, Text4Baby Control Group
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity
Effect of Low-calorie Diet and Orange Juice on Body Weight and Metabolic Parameters of Obese Subjects
This study aimed to verify if combination of a low calorie diet and orange juice consumption results in weight loss and ameliorates metabolic obesity-related biomarkers.
- Trial name
- LCD-OJ-OBESE (NCT02914249)
- Testing
- Orange juice (500 mL/d)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Obesity, Weight Loss
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Obesity is a direct result of food-intake in excess of body energy expenditure. Thus, induction of increased energy expenditure via the activation of thermogenesis at targeted anatomical sites can counterbalance obesity.
- Conditions
- Obesity, Weight Loss, Overweight and Obesity
- Trial name
- NCT03171415
- Testing
- RZL-012
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raziel Therapeutics Ltd.